Supplementary tables for

Slater, et al. (2009).
'Genome sequences of three Agrobacterium biovars elucidate the evolution of multichromosome genomes'
J.Bacteriol (Accepted)


Table S1. A. tumefaciens C58 genome feature summary.

Table S2. A. vitis S4 genome feature summary.

Table S3. A. radiobacter K84 genome feature summary.

Table S4. Genomes used for phylogenetic reconstruction among the Rhizobiaceae with outgroups in the Rhizobiales.

Table S5. Homology groups used to construct the species phylogeny. Each of these 509 groups contains a single gene in at least 17 of the 19 taxa under analysis and this gene is on the main chromosome within the Rhizobiaceae. Genbank protein accessions or genome-project protein identifiers are given for each genome identified by Genbank taxon ID (see Table S4). Rows correspond to gene families and columns correspond to genomes.

Table S6. Key gene clusters shared by chromosome II in several strains of Brucella (represented by B. suis 1330), chromosome II in Ochrobactrum anthropi, chromosome II in biovar 1 (C58) and 3 (S4) strains of Agrobacterium, 2651 kbp replicon in biovar 2 (K84) of Agrobacterium, plasmid p42e of Rhizobium etli (R. etli), plasmid pRL11 of Rhizobium leguminosarum (R. legum), and plasmid pSymB of Sinorhizobium (S. mel), most likely due to a shared repABC-type plasmid precursor (labeled IRT in the research article) that either entered an ancestral genome carrying these gene clusters and/or resulted from an ancestral intragenome gene transfer from chromosome I to the IRT plasmid early in the Rhizobiales lineage.

Table S7. Key gene clusters shared by chromosome I of Sinorhizobium meliloti (extant representative of ancestral chromosome I) and by chromosome II of all sequenced Brucella strains (Brucella abortus biovar 1 strain 9-941 used as an example) and chromosome II of Ochrobactrum anthropi. These gene clusters are presumed to have moved from the ancestral chromosome I to the IRT plasmid-derived chromosome II prior to the divergence of the Brucella and Ochrobactrum clades.

Table S8. Key gene clusters shared by chromosome I of Sinorhizobium meliloti (extant representative of ancestral chromosome I) and by chromosome II of all sequenced Brucella strains (Brucella abortus biovar 1 strain 9-941 used as an example), but not shared by chromosome II of Ochrobactrum anthropi. These gene clusters are presumed to have moved from the ancestral chromosome I to the plasmid-derived chromosome II in the Brucella lineage after its divergence from the Ochrobactrum clade.

Table S9. First gene cluster: shared by chromosome II in Agrobacterium strains and by pSymB in Sinorhizobium meliloti. This gene cluster most likely moved from the ancestral chromosome I onto the pSymB precursor before the split of the Sinorhizobium lineage away from the rest of the Rhizobiaceae lineage. Remaining gene clusters: shared by chromosome I in Agrobacterium strains (extant examples of ancestral chromosome I) and by pSymB in Sinorhizobium meliloti. These gene clusters most likely moved from the ancestral chromosome I onto the pSymB precursor after the split of the Sinorhizobium lineage away from the rest of the Rhizobiaceae lineage.

Table S10. Key gene clusters shared by chromosome I in S. meliloti (extant examples of ancestral chromosome I), chromosome II in biovar 1 (C58) and 3 (S4) strains of Agrobacterium, the 2651 kbp replicon in biovar 2 (K84) of Agrobacterium, plasmid p42e of Rhizobium etli (Ret), and plasmid pRL11 of Rhizobium leguminosarum (Rleg), most likely due to an ancestral intragenome gene transfer from chromosome I to a repABC-type IRT plasmid in the Agrobacterium/Rhizobium lineage.

Table S11. Key gene cluster shared by chromosome II in biovar 1 and 3 strains of Agrobacterium and by chromosome I in S. meliloti and Agrobacterium bv. 2 (K84), most likely due to an ancestral intragenome gene transfer from chromosome I to chromosome II in the lineage that includes biovars 1 and 3 after this lineage diverged away from biovar 2.

Table S12. Key gene clusters shared by chromosome I in S. meliloti or Agrobacterium bv. 2 (K84) or Agrobacterium bv. 3 (S4) (extant examples of ancestral chromosome I) and by chromosome II in biovar 1 (C58), most likely due to an ancestral intragenome gene transfer from chromosome I to chromosome II in the biovar 1 lineage after it diverged from biovar 3 lineage.

Table S13. Key gene cluster shared by chromosome I in Agrobacterium biovar 1 (extant example of ancestral chromosome) and by the 2651 kbp replicon in biovar 2 (K84) of Agrobacterium, plasmid p42e of Rhizobium etli (Ret), and plasmid pRL11 of Rhizobium leguminosarum (Rleg), most likely due to an ancestral intragenome gene transfer from chromosome I to the repABC-type IRT plasmid in the biovar 2 lineage after it diverged from the biovar 1/biovar 3 lineage.

Table S14. Key gene clusters shared by chromosome II of all sequenced Vibrio strains (Vibrio cholerae O1 biovar eltor strain N16961 used as an example) and chromosome II of Photobacterium profundum, but not by chromosome I of Aeromonas hydrophila (extant representative of ancestral chromosome I), indicative of the plasmid progenitor of chromosome II. This plasmid would have entered the common ancestor prior to the divergence of the Vibrio and Photobacterium clades.

Table S15. Key gene clusters shared by chromosome I of Aeromonas hydrophila (extant representative of ancestral chromosome I) and by chromosome II of all sequenced Vibrio strains (Vibrio cholerae O1 biovar eltor strain N16961 used as an example) and chromosome II of Photobacterium profundum. These gene clusters are presumed to have moved from the ancestral chromosome I to the plasmid-derived chromosome II prior to the divergence of the Vibrio and Photobacterium clades.

Table S16. Key gene clusters shared by chromosome I of Aeromonas hydrophila (extant representative of ancestral chromosome I) and by chromosome II of all sequenced Vibrio strains (Vibrio cholerae O1 biovar eltor strain N16961 used as an example), but not shared by chromosome II of Photobacterium profundum. These gene clusters are presumed to have moved from the ancestral chromosome I to the plasmid-derived chromosome II in the Vibrio lineage after its divergence from the Photobacterium clade.

Table S17. Key gene clusters shared by chromosome I of Aeromonas hydrophila (extant representative of ancestral chromosome I) and by chromosome II of Photobacterium profundum, but not shared by chromosome II of sequenced Vibrio strains (Vibrio cholerae O1 biovar eltor strain N16961 used as an example). These gene clusters are presumed to have moved from the ancestral chromosome I to the plasmid-derived chromosome II in the Photobacterium lineage after its divergence from the Vibrio clade.

Table S18. Key gene clusters shared by chromosome II of all sequenced Burkholderia strains (Burkholderia cenocepacia AU1054 used as an example) and chromosome II of all sequenced Ralstonia strains (Ralstonia eutropha JMP134 used as an example), but not by chromosome I of Bordetella bronchiseptica RB50 (extant representative of ancestral chromosome I), indicative of the plasmid progenitor of chromosome II. This plasmid would have entered the common ancestor prior to the divergence of the Burkholderia and Ralstonia clades.

Table S19. Key gene clusters shared by chromosome I of Bordetella bronchiseptica RB50 (extant representative of ancestral chromosome I) and by chromosome II of all sequenced Burkholderia strains (Burkholderia cenocepacia AU1054 used as an example) and chromosome II of all sequenced Ralstonia strains (Ralstonia eutropha JMP134 used as an example). These gene clusters are presumed to have moved from the ancestral chromosome I to the plasmid-derived chromosome II prior to the divergence of the Burkholderia and Ralstonia clades.

Table S20. Key gene clusters shared by chromosome I of Bordetella bronchiseptica RB50 (extant representative of ancestral chromosome I) and by chromosome II of all sequenced Burkholderia strains (Burkholderia cenocepacia AU1054 used as an example), but not shared by chromosome II of Ralstonia strains (Ralstonia eutropha JMP134 used as an example). These gene clusters are presumed to have moved from the ancestral chromosome I to the plasmid-derived chromosome II in the Burkholderia lineage after its divergence from the Ralstonia clade.

Table S21. Key gene clusters shared by chromosome I of Bordetella bronchiseptica RB50 (extant representative of ancestral chromosome I) and by chromosome II of Ralstonia strains (Ralstonia eutropha JMP134 used as an example), but not shared by chromosome II of sequenced Burkholderia strains (Burkholderia cenocepacia AU1054 used as an example). These gene clusters are presumed to have moved from the ancestral chromosome I to the plasmid-derived chromosome II in the Ralstonia lineage after its divergence from the Burkholderia clade.

Table S22. Key gene clusters shared by chromosome I or chromosome II of Burkholderia pseudomallei 1710b (extant representative of bichromosomal background) and by chromosome III of those sequenced Burkholderia strains with a chromosome III (Burkholderia cenocepacia AU1054 used as an example). These gene clusters are presumed to have moved from the ancestral chromosome I or from chromosome II to the plasmid-derived chromosome III in the Burkholderia sublineage that evolved a chromosome III.






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Table S1. A. tumefaciens C58 genome feature summary.

 

Chromosome 1

Chromosome 2

pATC58

pTiC58

size (bp)

2,841,580

2,075,577

542,869

214,234

% GC content

59.4

59.3

57.3

56.7


protein coding genes

total

2,768

1,861

557

199

functionality assigned

1,739

1,295

342

140

conserved hypothetical

749

362

130

140

hypothetical

280

204

85

13

pseudogenes

3

8

15

2


RNA genes

rRNA operons

2

2

0

0

tRNAs

40

15

0

0

other RNAa

16

9

0

0


genomic islands

total

15

10

9

4

average size (bp)

20.3

24.6

21.0

38.5

a Includes tmRNAs, SRP RNAs, suhB, riboswitches and miscellaneous features.



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Table S2. A. vitis S4 genome feature sumamry.

 

Chromosome1

Chromosome2

Plasmid1
(631k)

Plasmid2
(259k)

Plasmid3
(212k)

Plasmid4
(130k)

Plasmid5
(79k)

size (bp)

3,726,375

1,283,187

631,775

258,824

211,620

130,435

78,730

% GC content

57.7

57.5

56.6

56.7

58.6

56.2

56.8


protein coding genes

total

3,250

1,061

543

237

197

109

82

functionality assigned

2,185

830

430

203

148

57

44

conserved hypothetical

887

185

95

24

37

30

24

hypothetical

178

46

18

10

12

22

14

pseudogenes

16

7

14

32

19

2

0


RNA genes

rRNA operons

2

2

0

0

0

0

0

tRNAs

47

7

0

0

0

0

0

other RNAa

19

8

1

1

0

1

0


genomic islands

total

13

2

2

2

1

0

0

average size (bp)

35.7

26.1

29.5

36.7

11.8

0

0

a Includes tmRNAs, SRP RNAs, suhB, riboswitches and miscellaneous features.



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Table S3. A. radiobacter K84 genome feature summary.

 


Chromosome1


Megareplicon
2a


pAgK84A


pAgK84B


pAgK84C

size (bp)

4,005,130

2,650,913

44,420

184,668

388,169

% GC content

60.3

59.8

53.5

59.0

57.0


protein coding genes

total

3,784

2,382

36

177

373

functionality assigned

2,761

1,911

28

124

275

conserved hypothetical

785

327

2

40

47

hypothetical

238

144

6

13

51

pseudogenes

40

19

1

1

7


RNA genes

rRNA operons

3

0

0

0

0

tRNAs

51

0

0

0

0

other RNAb

19

4

0

0

0


genomic islands

total

25

26

1

2

5

average size (bp)

32.2

22.9

46.3

34.5

28.9

a This replicon does not meet our definition of a chormosome (see Results).
b Includes tmRNAs, SRP RNAs, suhB, riboswitches and miscellaneous features.



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Table S4. Genomes used for phylogenetic reconstruction among the Rhizobiaceae with outgroups in the Rhizobiales.


Genbank Taxon ID Taxon Name
311402 Agrobacterium vitis S4
311403 Agrobacterium radiobacter K84
176299 Agrobacterium tumefaciens str. C58
347834 Rhizobium etli CFN 42
266834 Sinorhizobium meliloti 1021
266835 Mesorhizobium loti MAFF303099
387 Rhizobium leguminosarum bv. viciae
266779 Mesorhizobium sp. BNC1
262698 Brucella abortus biovar 1 str. 9-941
224914 Brucella melitensis 16M
283165 Bartonella quintana str. Toulouse
314269 Aurantimonas sp. SI85-9A1
224911 Bradyrhizobium japonicum USDA 110
316055 Rhodopseudomonas palustris BisA53
323097 Nitrobacter hamburgensis X14
78245 Xanthobacter autotrophicus Py2
402881 Parvibaculum lavamentivorans DS-1
438753 Azorhizobium caulinodans ORS 571
439375 Ochrobactrum anthropi ATCC 49188




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Table S5. Homology groups used to construct the species phylogeny. Each of these 509 groups contains a single gene in at least 17 of the 19 taxa under analysis and this gene is on the main chromosome within the Rhizobiaceae. Genbank protein accessions or genome-project protein identifiers are given for each genome identified by Genbank taxon ID (see Table S4). Rows correspond to gene families and columns correspond to genomes.
Agro. Vit. S4 Agro. Rad. K84 Agro. Tum. C58 Rhiz. Leg. Rhizo. etli Sinorhizo Bruc. Mel. Bruc. Abor. Ochrobactrum Bartonella Meso. BNC1 Mesorhizo Aurantimonas Rhodopseud Nitrobacter Brady. Jap. Xanth. Aut. Azorhizobium Parvibaculum
311402 311403 176299 387 347834 266834 224914 262698 439375 283165 266779 266835 314269 316055 323097 224911 78245 438753 402881



















Avi0636 Arad4034
YP_766228 YP_468130 NP_384722 NP_540590 YP_221041 YP_001368881 YP_032670 YP_672755 NP_106959
YP_783380 YP_575649 NP_767900 YP_001417621 YP_001526060 YP_001411809
Avi4197 Arad4404 NP_533359 YP_770109 YP_471426 NP_387344 NP_539050 YP_222580 YP_001369476 YP_032863 YP_675926 NP_105219 ZP_01229026 YP_779259 YP_578763 NP_767116 YP_001415327 YP_001526625 YP_001412691
Avi1441 Arad1586 NP_531726 YP_767109 YP_468914 NP_385170 NP_540214 YP_221404 YP_001371179 YP_032102 YP_673507 NP_108005 ZP_01228762 YP_781944 YP_577508 NP_771706 YP_001418718 YP_001524169 YP_001414131
Avi0960 Arad1161 NP_531347 YP_766559 YP_468424 NP_384964 NP_540436 YP_221194 YP_001369089 YP_032032 YP_673284 NP_107762 ZP_01228047 YP_783512 YP_578368 NP_774138 YP_001416317 YP_001525302 YP_001411899
Avi0934 Arad1121 NP_531417 YP_766540 YP_468405 NP_384944 NP_540460 YP_221168 YP_001369063 YP_032004 YP_673264 NP_107736 ZP_01228067 YP_783675 YP_575626 NP_767825 YP_001416877 YP_001527179 YP_001411974
Avi4198 Arad4405 NP_533360 YP_770110 YP_471427 NP_387345 NP_539051 YP_222579 YP_001369477 YP_032862 YP_675927 NP_105218 ZP_01229027 YP_779260 YP_578764 NP_767117 YP_001415326 YP_001526626 YP_001412692
Avi0436 Arad0654 NP_531061 YP_766003 YP_467926 NP_384510 NP_540894 YP_222783 YP_001369310
YP_676450 NP_106182 ZP_01228450 YP_783085 YP_576045
YP_001416721 YP_001522923 YP_001414871
Avi0053 Arad0036 NP_530740 YP_765632 YP_467588 NP_384142 NP_540942 YP_222736 YP_001369370
YP_676113 NP_105809 ZP_01228490 YP_779401 YP_575417 NP_767394 YP_001418184 YP_001523628 YP_001411416
Avi0031 Arad0063 NP_530760 YP_765655 YP_467609 NP_384164 NP_540965 YP_222716 YP_001369392 YP_031905 YP_676026 NP_105744 ZP_01228888 YP_779311 YP_575481 NP_767286 YP_001417196 YP_001523137 YP_001412517
Avi0930 Arad1119 NP_531415 YP_766538 YP_468403 NP_384942 NP_540462 YP_221166 YP_001369061 YP_032002 YP_673262 NP_107734
YP_783677 YP_575628 NP_767827 YP_001416879 YP_001527177 YP_001411976
Avi2208 Arad2475 NP_532431 YP_768114 YP_469708 NP_385527 NP_539828 YP_221783 YP_001370702 YP_032215 YP_673567 NP_102620 ZP_01225706 YP_781267 YP_576933 NP_772163 YP_001416552 YP_001523859 YP_001413931
Avi1843 Arad1975 NP_532623 YP_767381 YP_469200 NP_385465 NP_539677 YP_221934 YP_001370504 YP_032443 YP_674235 NP_102123 ZP_01225673 YP_782493 YP_576830 NP_772037 YP_001416584 YP_001525467 YP_001414004
Avi4110 Arad4310 NP_533290 YP_769980 YP_471346 NP_387143 NP_539166 YP_222460 YP_001369651 YP_032755 YP_675752 NP_105026 ZP_01226749 YP_779222 YP_575883 NP_767083 YP_001416978 YP_001527044 YP_001412739
Avi1730 Arad1865 NP_531974 YP_767319 YP_469145 NP_385386 NP_540061 YP_221558 YP_001370952 YP_032233 YP_673598 NP_102958 ZP_01225741 YP_781455 YP_577458 NP_771543 YP_001419496
YP_001414475
Avi1862 Arad1998 NP_532608 YP_767397 YP_469216 NP_385481 NP_539693 YP_221918 YP_001370520 YP_032427 YP_674219 NP_102139 ZP_01225660 YP_782477 YP_576846 NP_772021 YP_001419654 YP_001525451 YP_001414020
Avi0391 Arad0601 NP_531030 YP_765982 YP_467907 NP_384474 NP_540860 YP_220785 YP_001368563 YP_031830 YP_672571 NP_106217 ZP_01228409 YP_778942 YP_575363 NP_767470 YP_001414917 YP_001523930 YP_001411283
Avi1818 Arad1955 NP_532641 YP_767364 YP_469184 NP_385449 NP_539661 YP_221952 YP_001370487 YP_032354 YP_674382 NP_102105 ZP_01225687 YP_782518 YP_576808 NP_772056 YP_001418245 YP_001523798 YP_001413989
Avi0642 Arad4039 NP_531238 YP_766224 YP_468126 NP_384718 NP_540586 YP_221045 YP_001368885
YP_672759 NP_106963 ZP_01227806 YP_783384 YP_575645 NP_767897 YP_001416138 YP_001526064 YP_001411802
Avi1724 Arad1858 NP_531969 YP_767314 YP_469140 NP_385381 NP_540066 YP_221553 YP_001370957 YP_032228 YP_673593 NP_102963 ZP_01225746 YP_781450 YP_577463 NP_771548 YP_001419501 YP_001524593 YP_001414480
Avi1902 Arad2577 NP_532525 YP_768192 YP_469788 NP_385880 NP_540041 YP_221580 YP_001370927 YP_032378 YP_673840 NP_101945 ZP_01228846 YP_780539 YP_576914 NP_772363 YP_001418970 YP_001525146 YP_001413852
Avi2283 Arad2183 NP_532484 YP_767699 YP_469399 NP_385825 NP_539647 YP_221969 YP_001370467
YP_674293 NP_102023 ZP_01227450 YP_781837 YP_577401 NP_771039 YP_001419050 YP_001524850 YP_001414215
Avi2155 Arad2423 NP_532188 YP_768061 YP_469670 NP_385710 NP_539906 YP_221709 YP_001370622 YP_032262 YP_674141 NP_102223 ZP_01225591 YP_781782 YP_577269 NP_771158 YP_001419203 YP_001525089 YP_001414374
Avi0992 Arad1193 NP_531436 YP_766582 YP_468449 NP_384985 NP_540414 YP_221215 YP_001369108 YP_032041 YP_673301 NP_107787 ZP_01228037 YP_779998 YP_576116 NP_769289 YP_001419041 YP_001526024 YP_001412062
Avi3526 Arad3502
YP_769336 YP_470823 NP_386823 NP_539339 YP_222273 YP_001370113 YP_032545 YP_674771 NP_104065 ZP_01226948 YP_783173 YP_578559 NP_768842 YP_001418375 YP_001524117 YP_001413447

Arad1591 NP_531730 YP_767113 YP_468918 NP_385176 NP_540206 YP_221412 YP_001371171 YP_032106 YP_673510 NP_108010
YP_781941 YP_577505 NP_771703 YP_001418760 YP_001524918 YP_001414136
Avi2880 Arad2982 NP_532759 YP_768875 YP_470333 NP_386272 NP_539504 YP_222108 YP_001370297 YP_032490 YP_674557 NP_103107 ZP_01226098 YP_781042 YP_576573 NP_773234 YP_001415245 YP_001527483 YP_001413696
Avi1102 Arad1288 NP_531503 YP_766696 YP_468541 NP_385038 NP_540353 YP_221273 YP_001369240 YP_032058 YP_673337 NP_107826 ZP_01228001 YP_783309 YP_578694 NP_769178 YP_001415409 YP_001523326 YP_001412009
Avi4143 Arad4354 NP_533315 YP_770060 YP_471375 NP_387183 NP_539092 YP_222539 YP_001369523 YP_031838 YP_675741 NP_105147 ZP_01228974 YP_779007 YP_575910 NP_767208 YP_001416062 YP_001523179 YP_001412620
Avi2131 Arad2262 NP_532133 YP_767848 YP_469458 NP_385562 NP_539780 YP_221827 YP_001370614 YP_032176 YP_674181 NP_102198 ZP_01227542 YP_781672 YP_577108 NP_771125 YP_001419280 YP_001526005 YP_001414396
Avi1867 Arad2005 NP_532603 YP_767402 YP_469221 NP_385486 NP_539698 YP_221913 YP_001370525 YP_032422 YP_674214 NP_102144 ZP_01225655 YP_782472 YP_576851 NP_772016 YP_001419649 YP_001525446 YP_001414025
Avi3127 Arad3136 NP_532855 YP_769002 YP_470463 NP_385679 NP_539425 YP_222186 YP_001370205 YP_032532 YP_674675 NP_103881 ZP_01225947 YP_782867 YP_578104 NP_774018 YP_001417648 YP_001524062 YP_001413583
Avi2029 Arad2779 NP_532286 YP_768402 YP_469982 NP_386048 NP_540028 YP_221594 YP_001370914 YP_032193 YP_673881 NP_102824 ZP_01226011 YP_780947 YP_576788 NP_770451 YP_001416169 YP_001525319
Avi4144 Arad4355 NP_533316 YP_770061 YP_471376 NP_387184 NP_539093 YP_222538 YP_001369524 YP_032824 YP_675740 NP_105146 ZP_01228975 YP_779006 YP_575911 NP_767207 YP_001416063 YP_001523178 YP_001412625
Avi1927 Arad2602 NP_532540 YP_768208 YP_469819 NP_385893 NP_540050 YP_221570 YP_001370939 YP_032266 YP_673831 NP_101930 ZP_01228838 YP_780560 YP_576922 NP_772346 YP_001418974 YP_001525140 YP_001413848
Avi2467 Arad2628 NP_532049 YP_768227 YP_469836 NP_385910 NP_539866 YP_221751 YP_001370667 YP_032371 YP_673980 NP_102506 ZP_01228827 YP_780463 YP_576630 NP_772474 YP_001419514 YP_001524580 YP_001413824
Avi4205 Arad4412 NP_533364 YP_770114 YP_471431 NP_387348 NP_539145 YP_222480 YP_001369628 YP_032816 YP_675875 NP_105264 ZP_01229030 YP_779267 YP_578768 NP_767122 YP_001416368 YP_001526868 YP_001412696
Avi1682 Arad1812 NP_531940 YP_767277 YP_469100 NP_385349 NP_540085 YP_221534 YP_001371037 YP_032304 YP_673725 NP_108552 ZP_01225964 YP_781774 YP_577705 NP_771603 YP_001419222 YP_001525106 YP_001414201
Avi0111 Arad0185 NP_530804 YP_765738 YP_467677 NP_384337 NP_540826 YP_220814 YP_001368582 YP_031927 YP_676588 NP_106159 ZP_01227696 YP_783711 YP_575813 NP_774755 YP_001417068 YP_001523060 YP_001411536
Avi4378 Arad4933 NP_533411 YP_770290 YP_471583 NP_387434 NP_539220 YP_222402 YP_001369722 YP_032711 YP_675950 NP_104799 ZP_01226843 YP_783037 YP_578930 NP_767953 YP_001417254 YP_001524386 YP_001413361
Avi1721 Arad1855 NP_531967 YP_767312 YP_469138 NP_385379 NP_540068 YP_221551 YP_001370959 YP_032226 YP_673591 NP_102965 ZP_01225748 YP_781448 YP_577465 NP_771550 YP_001419503 YP_001524591 YP_001414482
Avi4242 Arad4454 NP_533420 YP_770132 YP_471448 NP_387293 NP_539083 YP_222548 YP_001369507 YP_032771 YP_675776 NP_105165 ZP_01228958 YP_779346 YP_575449 NP_767243 YP_001417112 YP_001527145 YP_001412585
Avi0430 Arad0649 NP_531057 YP_766007 YP_467930 NP_384507 NP_540725 YP_220911 YP_001368713 YP_032638 YP_676569 NP_106002 ZP_01228453 YP_779151 YP_575378 NP_767440 YP_001416725 YP_001527619 YP_001414866
Avi1833 Arad1966 NP_532631 YP_767373 YP_469192 NP_385457 NP_539669 YP_221942 YP_001370496 YP_032451 YP_674243 NP_102115 ZP_01225680 YP_782501 YP_576822 NP_772045 YP_001416576 YP_001525475 YP_001413996
Avi0196 Arad0434 NP_530957 YP_765869 YP_467807 NP_384385 NP_539271 YP_222344 YP_001369812 YP_032701 YP_676604 NP_105432
YP_783061 YP_578454 NP_774535 YP_001416912 YP_001527001
Avi1535 Arad1675 NP_531798 YP_767167 YP_468978 NP_385253 NP_540386 YP_221242 YP_001369136 YP_032137 YP_674322 NP_108089 ZP_01227406 YP_782214 YP_577600 NP_770728 YP_001418023 YP_001527234 YP_001414615
Avi1552 Arad1702 NP_531819 YP_767184 YP_469002 NP_385270 NP_540173 YP_221449 YP_001371136 YP_032148 YP_674537 NP_108130 ZP_01227418 YP_782200 YP_577379 NP_770759 YP_001417228 YP_001527071 YP_001414594
Avi2668 Arad2126 NP_532390 YP_767644 YP_469343 NP_385635 NP_540001 YP_221620 YP_001370888 YP_032152 YP_674365 NP_102752
YP_781613 YP_577062 NP_771391 YP_001419285 YP_001524652 YP_001414291
Avi0109 Arad0187 NP_530806 YP_765740 YP_467679 NP_384335 NP_540824 YP_220816 YP_001368580
YP_676590 NP_106157 ZP_01227693 YP_783713 YP_575811 NP_774762 YP_001417525 YP_001523057 YP_001413950
Avi2513 Arad2232 NP_532074 YP_767825 YP_469436 NP_385611 NP_539750 YP_221857 YP_001370584 YP_032329 YP_673952 NP_102401 ZP_01227512 YP_781482 YP_576981 NP_771489 YP_001419306 YP_001524620 YP_001414447
Avi4389 Arad4941 NP_533496 YP_770300 YP_471592 NP_387443 NP_538925 YP_222698 YP_001369410 YP_032870 YP_676007 NP_105343 ZP_01228906 YP_779323 YP_575466 NP_767273 YP_001416736 YP_001527625 YP_001412551
Avi2929 Arad3030 NP_532799 YP_768912 YP_470368 NP_386307 NP_539470 YP_222141 YP_001370263 YP_032509 YP_674591 NP_103156 ZP_01226145 YP_780963 YP_578139 NP_773325 YP_001418360 YP_001526706 YP_001413659
Avi0368 Arad0561 NP_531020 YP_765952 YP_467879 NP_384451 NP_539275 YP_222340 YP_001369808 YP_032702 YP_676594 NP_106025 ZP_01228402 YP_779405 YP_575413 NP_767398 YP_001414993 YP_001523623 YP_001414910
Avi0427 Arad0647 NP_531055 YP_766009 YP_467932 NP_384505 NP_540723 YP_220913 YP_001368715 YP_032636 YP_676567 NP_106004 ZP_01228455 YP_779156 YP_575374 NP_767442 YP_001417972 YP_001527217 YP_001414863
Avi0199 Arad0437 NP_530959 YP_765871 YP_467809 NP_384387 NP_540928 YP_222749 YP_001369355 YP_031770 YP_673235 NP_105791 ZP_01228370 YP_779440 YP_575439 NP_767351 YP_001416993 YP_001523469 YP_001411484
Avi3111 Arad3127 NP_532843 YP_768991 YP_470451 NP_386426 NP_539443 YP_222167 YP_001370228 YP_032523 YP_674641 NP_103823 ZP_01225945 YP_779915 YP_578099 NP_774011 YP_001416149 YP_001526554 YP_001413585
Avi1450 Arad1595 NP_531733 YP_767116 YP_468921 NP_385179 NP_540203 YP_221416 YP_001371168 YP_032109 YP_673513 NP_108013 ZP_01228768 YP_781938 YP_577502 NP_771700 YP_001418763 YP_001524921 YP_001414139
Avi4387 Arad4940 NP_533495 YP_770299 YP_471591 NP_387442 NP_538926 YP_222697 YP_001369411 YP_032869 YP_676006 NP_105342 ZP_01228907 YP_779324 YP_575465 NP_767272 YP_001416737 YP_001527626 YP_001412552
Avi1865 Arad2003 NP_532605 YP_767400 YP_469219 NP_385484 NP_539696 YP_221915 YP_001370523 YP_032424 YP_674216 NP_102142 ZP_01225657 YP_782474 YP_576849 NP_772018 YP_001419651 YP_001525448 YP_001414023
Avi1499 Arad1640 NP_531772 YP_767150 YP_468958 NP_385230 NP_540405 YP_221224 YP_001369120 YP_032123 YP_673545 NP_108068 ZP_01227390 YP_782252 YP_577545 NP_770700 YP_001417299 YP_001523451 YP_001414743
Avi0928 Arad1115 NP_531413 YP_766536 YP_468401 NP_384940 NP_540464 YP_221164 YP_001369059 YP_032000 YP_673260 NP_107732 ZP_01228070 YP_783679 YP_575630 NP_767829 YP_001416881 YP_001527175 YP_001411978
Avi0250 Arad0309 NP_530920 YP_765796 YP_467733 NP_384686 NP_540753 YP_220886 YP_001368685 YP_031809 YP_674298 NP_105661 ZP_01228307
YP_578593 NP_768967 YP_001417265 YP_001526293
Avi0002
NP_530717 YP_765606 YP_467563 NP_384108 NP_540976 YP_222705 YP_001369403 YP_031732 YP_676015 NP_105350 ZP_01228899 YP_779318 YP_575474 NP_767278 YP_001416730 YP_001522918 YP_001412532
Avi2889 Arad2994 NP_532767 YP_768884 YP_470340 NP_386280 NP_539498 YP_222115 YP_001370291 YP_032496 YP_674563 NP_103113 ZP_01226104 YP_781034 YP_576567 NP_773240 YP_001415239 YP_001527476 YP_001413689
Avi1861
Atu8065 YP_767396 YP_469215 NP_385480 NP_539692 YP_221919 YP_001370519 YP_032428 YP_674220 NP_102138
YP_782478 YP_576845 NP_772022 YP_001419655 YP_001525452 YP_001414019
Avi3169 Arad3175
YP_769041 YP_470510 NP_386447 NP_539407 YP_222204 YP_001370186 YP_032023 YP_674705 NP_103959 ZP_01226187 YP_780359 YP_578302 NP_774093 YP_001417445 YP_001526896 YP_001413535
Avi1549 Arad1698 NP_531815 YP_767180 YP_468998 NP_385265 NP_540175 YP_221447 YP_001371138
YP_674313 NP_108140 ZP_01227416 YP_782201 YP_577588 NP_770758 YP_001416992 YP_001527028 YP_001414595
Avi1537 Arad1676 NP_531800 YP_767168 YP_468979 NP_385255 NP_540184 YP_221437 YP_001371148 YP_032138 YP_674321 NP_108091 ZP_01227407 YP_782210 YP_577597 NP_770742 YP_001417730 YP_001527236 YP_001414604
Avi4152 Arad4364
YP_770069 YP_471384 NP_387192
YP_222632 YP_001369539 YP_031866 YP_675908 NP_105091 ZP_01228996 YP_778990 YP_575956 NP_767191 YP_001415423 YP_001526233 YP_001412647
Avi4232 Arad4447 NP_533426 YP_770126 YP_471442 NP_387307 NP_538986 YP_222644 YP_001369512 YP_032768 YP_675770 NP_105158 ZP_01228967 YP_779335 YP_575453 NP_767258 YP_001415110 YP_001523009 YP_001412571
Avi1092 Arad1280 NP_531498 YP_766689 YP_468535 NP_385034 NP_540359 YP_221267 YP_001369167 YP_032055 YP_673330 NP_107820 ZP_01228004 YP_783337 YP_578422 NP_769139 YP_001416078 YP_001523372 YP_001411981
Avi2209 Arad2474 NP_532430
YP_469707 NP_385528 NP_539829 YP_221782 YP_001370701 YP_032214 YP_673568 NP_102618 ZP_01225705 YP_781263 YP_576931 NP_772165 YP_001416554 YP_001523861 YP_001413932
Avi1804 Arad1939 NP_532035 YP_767359 YP_469177 NP_385439 NP_539953 YP_221671 YP_001370795 YP_032312 YP_674331 NP_102069 ZP_01225697 YP_781279 YP_576940 NP_772155 YP_001416545 YP_001523869 YP_001413966

Arad0608 NP_531031 YP_765984 YP_467909 NP_384479 NP_540688 YP_220944 YP_001368745 YP_031773 YP_676545 NP_105451 ZP_01228558 YP_779294 YP_575510 NP_767312 YP_001417436 YP_001527207 YP_001414837
Avi2611 Arad2494 NP_532441 YP_768127 YP_469721 NP_385515 NP_539729 YP_221880 YP_001370562
YP_673929 NP_102428 ZP_01227491 YP_782326 YP_577675 NP_771803 YP_001419334 YP_001525745 YP_001414054
Avi1059 Arad1245 NP_531475 YP_766642 YP_468500 NP_385019 NP_540375 YP_221250 YP_001369150
YP_673314 NP_107805 ZP_01228017 YP_783035 YP_578928 NP_767955 YP_001417256 YP_001524383 YP_001411965
Avi1553 Arad1709 NP_531823 YP_767188 YP_469006 NP_385274 NP_540171 YP_221451 YP_001371134
YP_674536 NP_108128 ZP_01227419 YP_779863 YP_578339 NP_774113 YP_001417247 YP_001526885 YP_001413544
Avi2541 Arad2208 NP_532258 YP_767804 YP_469417 NP_385590 NP_539652 YP_221963 YP_001370472 YP_032272 YP_674287

YP_781234 YP_577820 NP_772225 YP_001418093 YP_001526375 YP_001413893
Avi2136 Arad2267 NP_532137 YP_767875 YP_469464 NP_385566 NP_539784 YP_221823 YP_001370756 YP_032178 YP_674177 NP_102202 ZP_01227546 YP_781676 YP_577112 NP_771129 YP_001419276 YP_001526000 YP_001414392
Avi2433 Arad2542 NP_532506 YP_768168 YP_469762 NP_385843 NP_539961 YP_221663 YP_001370803 YP_032247 YP_674342 NP_101906 ZP_01225606 YP_781887 YP_577582 NP_770975 YP_001419349 YP_001526533 YP_001414527
Avi2925 Arad3026 NP_532797 YP_768910 YP_470366 NP_386305 NP_539476 YP_222136 YP_001370268
YP_674586 NP_103141 ZP_01226133 YP_782681 YP_575720 NP_768059 YP_001417728 YP_001527256 YP_001413667
Avi4348 Arad4674 NP_533417 YP_770181 YP_471494 NP_387365 NP_539194 YP_222432 YP_001369681
YP_675913 NP_104868 ZP_01228198 YP_779067 YP_575855 NP_766798 YP_001417539 YP_001523147 YP_001412973
Avi1365 Arad1496 NP_531674 YP_767043 YP_468824 NP_385126 NP_540248 YP_221365 YP_001371209 YP_032076 YP_673462 NP_107957 ZP_01227058 YP_780859 YP_576722 NP_769768 YP_001416560 YP_001524051 YP_001412222
Avi1624 Arad1765 NP_531871 YP_767239 YP_469058 NP_385325 NP_540101 YP_221517 YP_001371065 YP_032207 YP_673703 NP_108518 ZP_01227326 YP_781739 YP_576863 NP_771664 YP_001419259 YP_001525214 YP_001414183
Avi1015 Arad1213 NP_531454 YP_766618 YP_468473 NP_385007 NP_540423 YP_221207 YP_001369099 YP_032037 YP_673295 NP_107773 ZP_01228032 YP_783489 YP_576111 NP_769271 YP_001419017 YP_001524665 YP_001412065
Avi4130 Arad4339 NP_533305 YP_770010 YP_471365 NP_387163 NP_539054 YP_222576 YP_001369479 YP_032860 YP_675930 NP_105212 ZP_01228933 YP_779240 YP_575896 NP_767097 YP_001415389 YP_001526933 YP_001412725
Avi2280 Arad2163 NP_532272 YP_767697 YP_469397 NP_385827 NP_539645 YP_221970 YP_001370465 YP_032303 YP_673552 NP_102625 ZP_01227080 YP_781851 YP_577559 NP_771017 YP_001419627 YP_001524767 YP_001414212
Avi1916 Arad2609 NP_532547 YP_768211 YP_469821 NP_385895 NP_539712 YP_221899 YP_001370541 YP_032267 YP_673830 NP_101926 ZP_01228837 YP_780564 YP_576923 NP_772342 YP_001418728 YP_001525138
Avi4294 Arad4927 NP_533489 YP_770285 YP_471578 NP_387429 NP_539152 YP_222473 YP_001369637 YP_032812 YP_675955 NP_105053 ZP_01228919 YP_778968 YP_575557 NP_767220 YP_001414955 YP_001527613 YP_001412598
Avi1373 Arad1503 NP_531680 YP_767049 YP_468829 NP_385131 NP_540242 YP_221371 YP_001371204 YP_032083 YP_673467 NP_107962 ZP_01228737 YP_780875 YP_576731 NP_769780 YP_001416529 YP_001526038 YP_001412236
Avi0010 Arad0011 NP_530724 YP_765613 YP_467570 NP_384115 NP_540969 YP_222712 YP_001369396
YP_676022 NP_105389 ZP_01228892 YP_779313 YP_575479 NP_767283 YP_001416950 YP_001527517 YP_001412524
Avi0936 Arad1124 NP_531420 YP_766542 YP_468406 NP_384945 NP_540459 YP_221169 YP_001369067 YP_032028 YP_673268 NP_107737 ZP_01228066 YP_783328 YP_578416 NP_769161 YP_001416172 YP_001525314 YP_001411983
Avi2855 Arad2967 NP_532745 YP_768865 YP_470322 NP_386263 NP_539508 YP_222104 YP_001370303 YP_032487 YP_674552 NP_103100 ZP_01226082 YP_781047 YP_577986 NP_773229 YP_001417201 YP_001523134 YP_001413700
Avi2525 Arad2220 NP_532065 YP_767816 YP_469427 NP_385602 NP_539741 YP_221867 YP_001370575 YP_032337 YP_673943 NP_102414 ZP_01227503 YP_781472 YP_576971 NP_771500 YP_001419316 YP_001524610 YP_001414458
Avi0006 Arad0004 NP_530720 YP_765609 YP_467566 NP_384111 NP_540973 YP_222708 YP_001369400 YP_031735 YP_676018 NP_105353 ZP_01228896 YP_779316 YP_575476 NP_767280 YP_001416733 YP_001522921 YP_001412528
Avi2159 Arad2416 NP_532185 YP_768057 YP_469666 NP_385706 NP_539903 YP_221713 YP_001370625 YP_032259 YP_674144 NP_102218 ZP_01225594 YP_781785 YP_577266 NP_771155 YP_001419208 YP_001525094 YP_001414378
Avi3228 Arad3218 NP_532925 YP_769078 YP_470545 NP_386470 NP_539378 YP_222232 YP_001370155
YP_674735 NP_104003 ZP_01226214 YP_779877 YP_578445 NP_769106 YP_001417842 YP_001526424 YP_001413506
Avi2894 Arad3000 NP_532772 YP_768889 YP_470345 NP_386285 NP_539493 YP_222120 YP_001370286 YP_032501 YP_674568 NP_103118 ZP_01226109 YP_781028 YP_576561 NP_773245 YP_001416749 YP_001527457 YP_001413684
Avi2599 Arad2051 NP_532416 YP_767547 YP_469275 NP_385661 NP_539860 YP_221758 YP_001370676
YP_673893 NP_101999 ZP_01225568 YP_781419 YP_577341 NP_770914 YP_001419551 YP_001524184 YP_001414561
Avi2219 Arad2470 NP_532428 YP_768111 YP_469703 NP_385532 NP_539833 YP_221779 YP_001370698 YP_032395 YP_673572 NP_102613 ZP_01225701 YP_781253 YP_576929 NP_772189 YP_001416539 YP_001523865
Avi1839
NP_532627 YP_767377 YP_469196 NP_385461 NP_539673 YP_221938 YP_001370500 YP_032447 YP_674239 NP_102119 ZP_01225676 YP_782497 YP_576826 NP_772041 YP_001416580 YP_001525471 YP_001414000
Avi4287 Arad4872 NP_533449 YP_770239 YP_471533 NP_387262 NP_539120 YP_222504 YP_001369600 YP_031849 YP_675996 NP_104991
YP_779494 YP_575865 NP_767061 YP_001417044 YP_001527009 YP_001412759
Avi1582 Arad1729 NP_531842 YP_767204 YP_469022 NP_385294 NP_540121 YP_221495 YP_001371085 YP_032386 YP_673681 NP_108317 ZP_01227436 YP_782193 YP_577371 NP_770761 YP_001418013 YP_001526581 YP_001414586
Avi3221 Arad3212 NP_532920 YP_769074 YP_470540 NP_385933 NP_539384 YP_222228 YP_001370161
YP_674726 NP_103997 ZP_01226211 YP_780249 YP_578441 NP_769121 YP_001417847 YP_001526419 YP_001413511
Avi1866 Arad2004 NP_532604 YP_767401 YP_469220 NP_385485 NP_539697 YP_221914 YP_001370524 YP_032423 YP_674215 NP_102143 ZP_01225656 YP_782473 YP_576850 NP_772017 YP_001419650 YP_001525447 YP_001414024
Avi0200 Arad0438 NP_530960 YP_765872 YP_467810 NP_384388 NP_540927 YP_222750 YP_001369354 YP_031769 YP_673236 NP_105790 ZP_01228369 YP_779439 YP_575438 NP_767350 YP_001416838 YP_001527360 YP_001411487
Avi4385 Arad4938 NP_533493 YP_770297 YP_471589 NP_387440 NP_538928 YP_222695 YP_001369413 YP_032867 YP_676004 NP_105340 ZP_01228909 YP_779326 YP_575463 NP_767270 YP_001416739 YP_001527628 YP_001412554
Avi4185 Arad4391 NP_533348 YP_770099 YP_471414 NP_387333 NP_540774 YP_220865 YP_001368662
YP_675891 NP_105234 ZP_01229016 YP_779247 YP_575757 NP_767104 YP_001418731 YP_001527379 YP_001412673
Avi0312 Arad0208 NP_530783 YP_765752 YP_467692 NP_384295 NP_540857 YP_220788 YP_001368566 YP_031932 YP_672574 NP_106214 ZP_01228412 YP_779182 YP_575407 NP_767405 YP_001419007 YP_001523151 YP_001414901
Avi1258 Arad1455 NP_531595 YP_766966 YP_468758 NP_385091 NP_540282 YP_221329 YP_001371232 YP_032063 YP_673427 NP_107919 ZP_01226729 YP_780298 YP_578130 NP_767016 YP_001417736 YP_001524000 YP_001412124
Avi2386 Arad2382 NP_532196 YP_767991 YP_469621 NP_385666 NP_539801 YP_221805 YP_001370727 YP_032408 YP_673961 NP_102478 ZP_01227561 YP_781681 YP_577038 NP_771336 YP_001419195 YP_001525244 YP_001414313

Arad0376 NP_530918 YP_765829 YP_467768 NP_384257 NP_540867 YP_222808 YP_001369283 YP_031900 YP_676483 NP_106238 ZP_01227681 YP_782668 YP_575734 NP_768070 YP_001415195 YP_001523195 YP_001411524
Avi0586 Arad0791 NP_531189 YP_766181 YP_468085 NP_384655 NP_540528 YP_221098 YP_001368964 YP_031980 YP_672664 NP_106297 ZP_01228324 YP_779658 YP_575905 NP_767780 YP_001414972 YP_001527556 YP_001411717
Avi2836 Arad2955 NP_532732 YP_768857 YP_470314 NP_386250 NP_539513 YP_222099 YP_001370309 YP_032484 YP_674546 NP_103075 ZP_01227096 YP_781061 YP_577978 NP_773201 YP_001416331 YP_001527391 YP_001413702
Avi0173 Arad0169 NP_530793 YP_765725 YP_467664 NP_384349 NP_540879 YP_222798 YP_001369295 YP_031908 YP_676466 NP_106202 ZP_01228427 YP_779133 YP_575396 NP_767420 YP_001415204 YP_001522980 YP_001414886
Avi1822 Arad1959 NP_532638 YP_767368 YP_469187 NP_385452 NP_539664 YP_221949 YP_001370490 YP_032351 YP_674379 NP_102108 ZP_01225684 YP_782509 YP_576811 NP_772052 YP_001418248 YP_001523801 YP_001413992
Avi2666 Arad2129 NP_532388 YP_767646 YP_469345 NP_385637 NP_540000 YP_221622 YP_001370886 YP_032154 YP_674363 NP_102750 ZP_01227295 YP_781615 YP_577064 NP_771389 YP_001419283 YP_001524654 YP_001414293
Avi1026 Arad1220 NP_531460 YP_766625 YP_468479 NP_385001 NP_540434 YP_221196 YP_001369091 YP_032034 YP_673289 NP_107767 ZP_01228028 YP_783494 YP_576106 NP_769264 YP_001417377 YP_001524113 YP_001412070
Avi0437 Arad0656 NP_531062 YP_766002 YP_467925 NP_384511 NP_540893 YP_222784 YP_001369309 YP_031923 YP_676451 NP_106183 ZP_01228449 YP_779146 YP_575383 NP_767435 YP_001416712 YP_001522924 YP_001414872
Avi2279 Arad2162 NP_532274 YP_767695 YP_469396 NP_385828 NP_539642 YP_221973 YP_001370462
YP_674480 NP_102629 ZP_01227078 YP_781854 YP_577561 NP_771002 YP_001418407 YP_001524764 YP_001414210
Avi4296 Arad4929 NP_533491 YP_770287 YP_471580 NP_387431 NP_539154 YP_222471 YP_001369639 YP_032814 YP_675953 NP_105051 ZP_01228917 YP_779832 YP_575597 NP_769090 YP_001414950 YP_001527617 YP_001412604
Avi0397 Arad0611 NP_531033 YP_765987 YP_467912 NP_384482 NP_540692 YP_220942 YP_001368742
YP_676548 NP_105448 ZP_01228556 YP_779292 YP_575512 NP_767314 YP_001417434 YP_001527205 YP_001414835
Avi1846 Arad1979 NP_532620 YP_767384 YP_469203 NP_385468 NP_539680 YP_221931 YP_001370507 YP_032440 YP_674232 NP_102126 ZP_01225671 YP_782490 YP_576833 NP_772034 YP_001416587 YP_001525464 YP_001414007
Avi4240 Arad4453 NP_533421 YP_770131 YP_471447 NP_387294 NP_539084 YP_222547 YP_001369508
YP_675775 NP_105164 ZP_01228959 YP_779345 YP_575448 NP_767244 YP_001417111 YP_001527144 YP_001414114

Arad1720 NP_531832 YP_767195 YP_469013 NP_385283 NP_540162 YP_221460 YP_001371123 YP_032151 YP_674528 NP_108111 ZP_01227425 YP_779857 YP_578345 NP_774107 YP_001417627 YP_001526055 YP_001413137
Avi1628 Arad1770 NP_531874 YP_767242 YP_469061 NP_385328 NP_540098 YP_221520 YP_001371062 YP_032209 YP_673706 NP_108521 ZP_01227329 YP_781742 YP_576866 NP_771661 YP_001419262 YP_001525211 YP_001414186
Avi0055 Arad0035 NP_530739 YP_765631 YP_467587 NP_384141 NP_540941 YP_222737
YP_031753 YP_676114 NP_105808 ZP_01228492 YP_779400 YP_575418 NP_767393
YP_001523629 YP_001411417
Avi4134 Arad4342 NP_533307 YP_770013 YP_471367 NP_387175 NP_539080 YP_222550 YP_001369504 YP_032796 YP_675780 NP_105173 ZP_01229060 YP_779453 YP_578807 NP_767155 YP_001416865 YP_001526662 YP_001412713
Avi1595 Arad1740 NP_531855 YP_767213 YP_469029 NP_385305 NP_540117 YP_221500 YP_001371081 YP_032383 YP_673685 NP_108473 ZP_01227439 YP_781934 YP_577499 NP_771697 YP_001418765 YP_001524923 YP_001414141
Avi4106 Arad4306 NP_533287 YP_769977 YP_471343 NP_387140 NP_539169 YP_222457 YP_001369654 YP_032752 YP_675755 NP_105023 ZP_01226746 YP_779219 YP_575879 NP_767080 YP_001416981 YP_001527041 YP_001412742
Avi1698 Arad1831 NP_531952 YP_767293 YP_469117 NP_385362 NP_539792 YP_221816 YP_001370750 YP_032182 YP_673731 NP_108565 ZP_01227310 YP_781429 YP_577480 NP_771583 YP_001418477 YP_001524525 YP_001414493

Arad4946 NP_533499 YP_770303 YP_471595 NP_387446 NP_538920 YP_222702 YP_001369406
YP_676011 NP_105347 ZP_01228901 YP_779320 YP_575472 NP_767276 YP_001416727 YP_001527632 YP_001412536
Avi0943 Arad1133 NP_531334 YP_766549 YP_468413 NP_384952 NP_540449 YP_221181 YP_001369079 YP_032008 YP_673276 NP_107745 ZP_01228060 YP_783320 YP_578410 NP_769171 YP_001416278 YP_001523823 YP_001412002
Avi2132 Arad2263 NP_532134 YP_767849 YP_469459 NP_385563 NP_539781 YP_221826 YP_001370615
YP_674180 NP_102199 ZP_01227543 YP_781673 YP_577109 NP_771126 YP_001419279 YP_001526004 YP_001414395
Avi2037 Arad2773 NP_532280 YP_768397 YP_469977 NP_386043 NP_540032 YP_221590 YP_001370918 YP_032189 YP_673876 NP_102828 ZP_01226015 YP_780942 YP_576784 NP_770447 YP_001416163 YP_001525325
Avi2819 Arad2910 NP_532722 YP_768836 YP_470294 NP_386231 NP_539526 YP_222085 YP_001370338 YP_032477 YP_674309 NP_103041 ZP_01227112 YP_781101 YP_577968 NP_773150 YP_001416325 YP_001527399 YP_001413715
Avi2892 Arad2997 NP_532770 YP_768887 YP_470343 NP_386283 NP_539495 YP_222118 YP_001370288 YP_032499 YP_674566 NP_103116 ZP_01226107 YP_781030 YP_576563 NP_773243 YP_001416096 YP_001527470 YP_001413686
Avi0998 Arad1202 NP_531447 YP_766588 YP_468454 NP_384988 NP_540420 YP_221209 YP_001369102 YP_032039 YP_673298 NP_107781 ZP_01228034 YP_780002 YP_576118 NP_769292 YP_001419621 YP_001526032 YP_001412059
Avi2087 Arad2682 NP_532296 YP_768277 YP_469882 NP_385959 NP_539888 YP_221729 YP_001370640 YP_032316 YP_674023 NP_102547 ZP_01225838 YP_780915 YP_576765 NP_770418 YP_001418113 YP_001525248 YP_001412374
Avi0156 Arad0179 NP_530802 YP_765736 YP_467675 NP_384339 NP_540827 YP_220813 YP_001368583 YP_031926 YP_676623 NP_106162 ZP_01227697 YP_783710 YP_575814 NP_774754 YP_001416741 YP_001523063 YP_001411538
Avi1036 Arad1224 NP_531465 YP_766630 YP_468488 NP_384998 NP_540385 YP_221243 YP_001369139 YP_032042 YP_673304 NP_107793 ZP_01228026 YP_783646 YP_575613 NP_767808

YP_001411946

Arad0209 NP_530782 YP_765753 YP_467693 NP_384294 NP_540858 YP_220787 YP_001368565 YP_031832 YP_672573 NP_106215 ZP_01228411 YP_778944 YP_575365 NP_767467 YP_001414919 YP_001523928 YP_001411285
Avi1556 Arad1711 NP_531825 YP_767190 YP_469008 NP_385276 NP_540169 YP_221453 YP_001371132 YP_032149 YP_674534 NP_108126 ZP_01227421 YP_779861 YP_578341 NP_774111 YP_001417245 YP_001526883 YP_001413546
Avi4386 Arad4939 NP_533494 YP_770298 YP_471590 NP_387441 NP_538927 YP_222696 YP_001369412 YP_032868 YP_676005 NP_105341 ZP_01228908 YP_779325 YP_575464 NP_767271 YP_001416738 YP_001527627 YP_001412553
Avi4136 Arad4346 NP_533309 YP_770015 YP_471369 NP_387177 NP_539078 YP_222552 YP_001369502 YP_032798 YP_675782 NP_105176 ZP_01229035 YP_779450 YP_578805 NP_767153 YP_001416867 YP_001526660 YP_001412711
Avi2557 Arad2617 NP_532553 YP_768220 YP_469829 NP_385904 NP_539706 YP_221905 YP_001370532 YP_032417 YP_673827 NP_101920 ZP_01228833 YP_780527 YP_576900 NP_772390 YP_001418960 YP_001525770 YP_001413845

Arad3221 NP_532927 YP_769080 YP_470547 NP_386472 NP_539376 YP_222234 YP_001370153 YP_032538 YP_674737 NP_104005 ZP_01226216 YP_779875 YP_578447 NP_769104 YP_001417840 YP_001526426 YP_001413504
Avi0019 Arad0024 NP_530732 YP_765624 YP_467580 NP_384133 NP_540934 YP_222746 YP_001369360
YP_673232 NP_105797 ZP_01228499 YP_779392 YP_575425 NP_767384 YP_001416594 YP_001523933 YP_001411424
Avi0951 Arad1148 NP_531339 YP_766555 YP_468419 NP_384957 NP_540447 YP_221183 YP_001369081 YP_032006 YP_673278 NP_107751 ZP_01228055 YP_783315 YP_578406 NP_769175 YP_001418216 YP_001523945 YP_001412007
Avi1820 Arad1958 NP_532639 YP_767366 YP_469186 NP_385451 NP_539663 YP_221950 YP_001370489 YP_032352 YP_674380 NP_102107 ZP_01225685 YP_782516 YP_576810 NP_772054 YP_001418247 YP_001523800 YP_001413991
Avi2512 Arad2233 NP_532075 YP_767826 YP_469437 NP_385612 NP_539751 YP_221856 YP_001370585 YP_032328 YP_673953 NP_102400 ZP_01227513 YP_781483 YP_576982 NP_771488 YP_001419305 YP_001524621 YP_001414446
Avi1384 Arad1510 NP_531685 YP_767055 YP_468834 NP_385137 NP_540238 YP_221375
YP_032085 YP_673471 NP_107967 ZP_01228743 YP_783326 YP_578414 NP_769163 YP_001417273 YP_001526410 YP_001411998
Avi1720 Arad1854 NP_531966 YP_767311 YP_469137 NP_385378 NP_540069 YP_221550 YP_001370960 YP_032225 YP_673590 NP_102966 ZP_01225749 YP_781447 YP_577466 NP_771551 YP_001419504 YP_001524590 YP_001414483
Avi0991 Arad1191 NP_531435 YP_766581 YP_468448 NP_384984 NP_540413 YP_221216 YP_001369109
YP_673302 NP_107788 ZP_01228038 YP_779996 YP_576115 NP_769288 YP_001419042 YP_001526023 YP_001412063
Avi4122 Arad4332 NP_533301 YP_770005 YP_471361 NP_387159 NP_539058 YP_222570 YP_001369483 YP_032856 YP_675934 NP_105204 ZP_01228938 YP_779236 YP_575892 NP_767092 YP_001415072 YP_001526929 YP_001412731
Avi0423 Arad0639 NP_531051 YP_766013 YP_467937 NP_384501 NP_540718 YP_220916 YP_001368719 YP_031815 YP_676563 NP_106014 ZP_01228459 YP_779185 YP_575963 NP_767564 YP_001414951 YP_001527630 YP_001414854
Avi4393 Arad4947 NP_533500 YP_765604 YP_471596 NP_387447 NP_538919 YP_222703 YP_001369405
YP_676012 NP_105348 ZP_01228900 YP_780244 YP_578162 NP_769039 YP_001416728 YP_001527633 YP_001412534
Avi2778 Arad2866 NP_532695 YP_768785 YP_470241 NP_386174 NP_539541 YP_222068 YP_001370358 YP_032470 YP_674057 NP_103001 ZP_01227129 YP_781117 YP_577959 NP_773137 YP_001416395 YP_001525290 YP_001413732
Avi4176 Arad4383 NP_533343 YP_770093 YP_471408 NP_387324 NP_540779 YP_220860 YP_001368656 YP_031777 YP_675885 NP_105240 ZP_01229010 YP_779241 YP_575897 NP_767098 YP_001415323 YP_001526628 YP_001412667
Avi4172 Arad4380 NP_533340 YP_770090 YP_471405 NP_387322 NP_540782 YP_220858 YP_001368652
YP_675882 NP_105243 ZP_01229008 YP_781624 YP_578816 NP_767171 YP_001415322 YP_001523671 YP_001412663
Avi1857 Arad1994 NP_532610 YP_767394 YP_469213 NP_385478 NP_539690 YP_221921 YP_001370517 YP_032430 YP_674222 NP_102136 ZP_01225662 YP_782480 YP_576843 NP_772024 YP_001419657 YP_001525454 YP_001414017
Avi1622 Arad1764 NP_531870 YP_767238 YP_469057 NP_385324 NP_540102 YP_221516 YP_001371066
YP_673702 NP_108517 ZP_01227325 YP_781732 YP_577435 NP_771666 YP_001419075 YP_001525985 YP_001414180
Avi2205 Arad2477 NP_532433 YP_768116 YP_469710 NP_385525 NP_539826 YP_221785 YP_001370704
YP_673565 NP_102622 ZP_01225708 YP_781269 YP_576935 NP_772161 YP_001416550 YP_001523857 YP_001413928
Avi1842 Arad1974 NP_532624 YP_767380 YP_469199 NP_385464 NP_539676 YP_221935 YP_001370503 YP_032444 YP_674236 NP_102122
YP_782494 YP_576829 NP_772038 YP_001416583 YP_001525468 YP_001414003
Avi1633 Arad1774 NP_531877 YP_767245 YP_469064 NP_385331 NP_540095 YP_221523 YP_001371058 YP_032212 YP_673709 NP_108524 ZP_01227332 YP_781745 YP_576869 NP_771658 YP_001419265 YP_001525208 YP_001414189
Avi0205 Arad0440 NP_530961 YP_765873 YP_467811 NP_384389 NP_540925 YP_222752 YP_001369352 YP_031800 YP_673238 NP_105788 ZP_01228367 YP_779437 YP_575437 NP_767348 YP_001416835 YP_001527363 YP_001411498
Avi1785 Arad1920 NP_532018 YP_767684 YP_469384 NP_385423 NP_539982 YP_221640 YP_001370821 YP_032359 YP_674278 NP_102049 ZP_01225626 YP_781912 YP_577085 NP_770925 YP_001418381
YP_001414557
Avi0168 Arad0174 NP_530797 YP_765730 YP_467669 NP_384344 NP_540883 YP_222794 YP_001369299 YP_031913 YP_676461 NP_106197 ZP_01228439 YP_779137 YP_575392 NP_767424 YP_001415209 YP_001522935 YP_001414882
Avi1742 Arad1876 NP_531982 YP_767327 YP_469153 NP_385395 NP_540054 YP_221567 YP_001370945 YP_032390 YP_673816 NP_102580 ZP_01227475 YP_781468 YP_576969 NP_771506 YP_001419162 YP_001524607 YP_001414460
Avi1794 Arad1932 NP_532029 YP_767345 YP_469171 NP_385434 NP_539974 YP_221648 YP_001370813 YP_032241 YP_674271 NP_102059 ZP_01225618 YP_781896 YP_577096 NP_770945

YP_001414540
Avi2144 Arad2273 NP_532142 YP_767880 YP_469469 NP_385573 NP_539837 YP_221776 YP_001370695
YP_674171 NP_102207 ZP_01225596 YP_781802 YP_577119 NP_771134 YP_001419269 YP_001524572 YP_001414385
Avi0347 Arad0538 NP_531004 YP_765937 YP_467863 NP_384438 NP_540916 YP_222761 YP_001369337
YP_673248 NP_105550 ZP_01228656 YP_779284 YP_576965 NP_767323 YP_001415272 YP_001523075 YP_001411425
Avi2514 Arad2231 NP_532073 YP_767824 YP_469435 NP_385610 NP_539749 YP_221858 YP_001370583 YP_032330 YP_673951 NP_102402 ZP_01227511 YP_781481 YP_576980 NP_771491 YP_001419307 YP_001524619 YP_001414448
Avi1449 Arad1593 NP_531732 YP_767115 YP_468920 NP_385178 NP_540204 YP_221414 YP_001371169 YP_032108 YP_673512 NP_108012 ZP_01228767 YP_781939 YP_577503 NP_771701 YP_001418762 YP_001524920 YP_001414138
Avi2801 Arad2897 NP_532711 YP_768824 YP_470285 NP_386219 NP_539535 YP_222076 YP_001370350
YP_674050 NP_103021 ZP_01227123 YP_781113 YP_577960 NP_773141 YP_001416394 YP_001525291 YP_001413731
Avi1905 Arad2574 NP_532524
YP_469786 NP_385879 NP_540040 YP_221581 YP_001370926 YP_032377 YP_673841 NP_101946 ZP_01228847 YP_780537 YP_576913 NP_772368 YP_001418971 YP_001525145 YP_001413853
Avi0931 Arad1120 NP_531416 YP_766539 YP_468404 NP_384943 NP_540461 YP_221167 YP_001369062 YP_032003 YP_673263 NP_107735 ZP_01228068 YP_783676 YP_575627 NP_767826 YP_001416878 YP_001527178 YP_001411975
Avi0638 Arad4035 NP_531235 YP_766227 YP_468129 NP_384721 NP_540589 YP_221042 YP_001368882 YP_032671 YP_672756 NP_106960 ZP_01228372 YP_783381 YP_575648 NP_767899 YP_001417620 YP_001526061 YP_001411807
Avi2139 Arad2271 NP_532140 YP_767878 YP_469467 NP_385570 NP_539789 YP_221819 YP_001370753 YP_032196 YP_674173 NP_102205
YP_781679 YP_577115 NP_771131 YP_001419271 YP_001525996 YP_001414388
Avi0048 Arad0041 NP_530745 YP_765636 YP_467592 NP_384146 NP_540948 YP_222731 YP_001369375 YP_031778 YP_676109 NP_105813 ZP_01228485 YP_779761 YP_575789 NP_774788 YP_001417746 YP_001526985 YP_001411395
Avi0453 Arad0708 NP_531094 YP_766063 YP_467990 NP_384556 NP_540565 YP_221064 YP_001368900
YP_672920 NP_105594 ZP_01227797 YP_779579 YP_578892 NP_774735 YP_001417747 YP_001526986 YP_001411585
Avi2128 Arad2259 NP_532131 YP_767846 YP_469456 NP_385560 NP_539777 YP_221829 YP_001370611 YP_032174 YP_674183 NP_102196 ZP_01227540 YP_781670 YP_577106 NP_771118 YP_001418779 YP_001524664 YP_001414399
Avi3141 Arad3145 NP_532859 YP_769009 YP_470470 NP_385672 NP_539430 YP_222180 YP_001370210 YP_032528 YP_674668 NP_103870 ZP_01225952 YP_782871 YP_578109 NP_774021 YP_001417651 YP_001524065
Avi0041 Arad0049 NP_530751 YP_765642 YP_467598 NP_384152 NP_540955 YP_222725 YP_001369381
YP_676037 NP_105819 ZP_01228478 YP_780351 YP_578362 NP_774126 YP_001415247 YP_001527491 YP_001411914
Avi1434 Arad1583 NP_531722 YP_767107 YP_468912 NP_385166 NP_540217 YP_221400 YP_001371182 YP_032100 YP_673504 NP_107999 ZP_01228758 YP_781947 YP_577512 NP_771710 YP_001418713 YP_001524160 YP_001414127
Avi0011 Arad0012 NP_530725 YP_765614 YP_467571 NP_384116 NP_540968 YP_222713 YP_001369395
YP_676023 NP_105390 ZP_01228891 YP_779312 YP_575480 NP_767284 YP_001416951 YP_001527518 YP_001412523
Avi1558 Arad1712 NP_531826 YP_767191 YP_469009 NP_385277 NP_540168 YP_221454 YP_001371131 YP_032150 YP_674533 NP_108125 ZP_01227422 YP_779860 YP_578342 NP_774110 YP_001417244 YP_001526882 YP_001413547
Avi1359 Arad1491 NP_531669 YP_767038 YP_468819 NP_385121 NP_540253 YP_221360 YP_001371214 YP_032072 YP_673457 NP_107952 ZP_01227053 YP_780853 YP_576716 NP_769762 YP_001418064 YP_001524046 YP_001412209
Avi4339 Arad4689 NP_533385 YP_770191 YP_471483 NP_387372 NP_539189 YP_222438 YP_001369676
YP_675964 NP_104813 ZP_01228207 YP_779115 YP_575972 NP_767587 YP_001415122 YP_001527369 YP_001413130
Avi0308 Arad0210 NP_530830 YP_765756 YP_467696 NP_384289 NP_540918 YP_222759 YP_001369340 YP_031786 YP_673245 NP_105553 ZP_01228668 YP_779287 YP_575517 NP_767320 YP_001415267 YP_001523605 YP_001414828
Avi0007 Arad0006 NP_530721 YP_765610 YP_467567 NP_384112 NP_540972 YP_222709 YP_001369399 YP_031817 YP_676019 NP_105386 ZP_01228895 YP_779315 YP_575477 NP_767281 YP_001416707 YP_001527588 YP_001412527
Avi2261 Arad2520 NP_532161 YP_768151 YP_469743 NP_385495 NP_539900 YP_221716 YP_001370628 YP_032415 YP_674208 NP_102152 ZP_01225648 YP_782457 YP_576856 NP_772006 YP_001419643 YP_001525440 YP_001414032
Avi1853 Arad1988 NP_532614 YP_767390 YP_469209 NP_385474 NP_539686 YP_221925 YP_001370513 YP_032434 YP_674226 NP_102132 ZP_01225666 YP_782484 YP_576839 NP_772028 YP_001419661 YP_001525458 YP_001414013
Avi3233 Arad3224 NP_532930 YP_769082 YP_470549 NP_386474 NP_539374 YP_222236 YP_001370151 YP_032540 YP_674739 NP_104007 ZP_01226218 YP_779873 YP_578449 NP_769102 YP_001417838 YP_001526428 YP_001413502
Avi2148 Arad2279 NP_532146 YP_767884 YP_469473 NP_385577 NP_540683 YP_220949 YP_001368750
YP_676523 NP_104382 ZP_01228957 YP_780693
NP_768119 YP_001416302 YP_001523841 YP_001412169
Avi1443 Arad1588 NP_531727 YP_767110 YP_468915 NP_385171 NP_540213 YP_221405 YP_001371178 YP_032103 YP_673508 NP_108006 ZP_01228763 YP_781943 YP_577507 NP_771705 YP_001418758 YP_001524916 YP_001414132
Avi1601 Arad1744 NP_531856 YP_767218 YP_469032 NP_385308 NP_540116 YP_221501 YP_001371080
YP_673688 NP_108476 ZP_01227441 YP_781928 YP_577494 NP_771679 YP_001419170 YP_001524456 YP_001414147
Avi0999 Arad1203 NP_531448 YP_766589 YP_468455 NP_384989 NP_540421 YP_221208 YP_001369101
YP_673297 NP_107780 ZP_01228033 YP_780003 YP_576119 NP_769293 YP_001416061 YP_001523330 YP_001412058
Avi3216 Arad3207 NP_532917 YP_769071 YP_470537 NP_385928 NP_539387 YP_222224 YP_001370165 YP_032535 YP_674728 NP_103994 ZP_01226209 YP_779883 YP_578437 NP_769124 YP_001417848 YP_001526418 YP_001413512
Avi2657 Arad2138 NP_532249 YP_767654 YP_469353 NP_385646 NP_539992 YP_221630 YP_001370878 YP_032159 YP_674354 NP_102740 ZP_01227303 YP_781822 YP_577075 NP_771373 YP_001419189 YP_001525808 YP_001414302
Avi0175 Arad0165 NP_530791 YP_765724 YP_467663 NP_384350 NP_540878 YP_222799 YP_001369294 YP_031907 YP_676467 NP_106203 ZP_01228426 YP_779132 YP_575397 NP_767419 YP_001415203 YP_001522979 YP_001414887
Avi2568 Arad2440 NP_532373 YP_768079 YP_469685 NP_385768 NP_539759 YP_221848 YP_001370592
YP_674200 NP_102385 ZP_01227520 YP_781507 YP_577007 NP_771451 YP_001419251 YP_001525119 YP_001414439
Avi1841 Arad1973 NP_532625 YP_767379 YP_469198 NP_385463 NP_539675 YP_221936 YP_001370502 YP_032445 YP_674237 NP_102121 ZP_01225674 YP_782495 YP_576828 NP_772039 YP_001416582 YP_001525469 YP_001414002
Avi1737 Arad1869 NP_531976 YP_767322 YP_469148 NP_385389 NP_540058 YP_221561 YP_001370949
YP_673601 NP_102954
YP_781458 YP_577455 NP_771540 YP_001419493 YP_001524601 YP_001414472
Avi1740 Arad1871 NP_531979 YP_767324 YP_469150 NP_385393 NP_540056 YP_221565 YP_001370947 YP_032236 YP_673603 NP_102952 ZP_01225734 YP_781463 YP_577448 NP_771516 YP_001419340 YP_001524603 YP_001414467
Avi2884 Arad2988 NP_532762 YP_768878 YP_470336 NP_386275 NP_539501 YP_222112 YP_001370294 YP_032493 YP_674560 NP_103110 ZP_01226101 YP_781039 YP_576570 NP_773237 YP_001415242 YP_001527479 YP_001413692
Avi2142 Arad2272 NP_532141 YP_767879 YP_469468 NP_385571 NP_539790 YP_221818 YP_001370752 YP_032197 YP_674172 NP_102206 ZP_01227550 YP_781680 YP_577116 NP_771132 YP_001419270 YP_001525995 YP_001414387
Avi4178 Arad4384 NP_533344 YP_770094 YP_471409 NP_387325 NP_540778 YP_220861 YP_001368657
YP_675886 NP_105239 ZP_01229011 YP_779242 YP_575898 NP_767099 YP_001416661 YP_001526681 YP_001412669
Avi3109 Arad3125 NP_532842 YP_768990 YP_470450 NP_386425 NP_539444 YP_222166 YP_001370229
YP_674640 NP_103822 ZP_01225944 YP_779916 YP_578098 NP_774009 YP_001416148 YP_001526555 YP_001413586
Avi0478 Arad0778 NP_531134 YP_766161 YP_468064 NP_384625 NP_540536 YP_221090 YP_001368956 YP_031820 YP_672577 NP_106271 ZP_01226856 YP_783781 YP_575584 NP_767740 YP_001416126 YP_001526942 YP_001411684
Avi4207 Arad4414 NP_533365 YP_770115 YP_471432 NP_387349 NP_539066 YP_222562 YP_001369493 YP_032802 YP_675979 NP_105194 ZP_01229032 YP_779268 YP_578769 NP_767123 YP_001417411 YP_001526869 YP_001412697
Avi2567 Arad2438 NP_532372 YP_768078 YP_469684 NP_385767 NP_539760 YP_221847 YP_001370593
YP_674199 NP_102384 ZP_01227521 YP_781508 YP_577008 NP_771450 YP_001419253 YP_001525121 YP_001414436
Avi3203 Arad3200 NP_532910 YP_769064 YP_470530 NP_385923 NP_539392 YP_222219 YP_001370170
YP_674721 NP_103984 ZP_01226204 YP_779885 YP_578435 NP_769126
YP_001526415 YP_001413515
Avi0064 Arad0075 NP_530766 YP_765662 YP_467616 NP_384172 NP_540733 YP_220904 YP_001368708
YP_676574 NP_105995 ZP_01228509 YP_779168 YP_575590 NP_767545 YP_001415220 YP_001527608 YP_001411297
Avi0398 Arad0612 NP_531034 YP_765988 YP_467913 NP_384483 NP_540693 YP_220941 YP_001368741 YP_031775 YP_676549 NP_105447 ZP_01228555 YP_779291 YP_575513 NP_767315 YP_001417433 YP_001527203 YP_001414834
Avi0033 Arad0060 NP_530758 YP_765652 YP_467607 NP_384161 NP_540962 YP_222718 YP_001369389
YP_676029 NP_105748 ZP_01228881 YP_779309 YP_575483 NP_767290 YP_001417193 YP_001527418 YP_001412514
Avi4135 Arad4345 NP_533308 YP_770014 YP_471368 NP_387176 NP_539079 YP_222551 YP_001369503 YP_032797 YP_675781 NP_105175 ZP_01229034 YP_779451 YP_578806 NP_767154 YP_001416866 YP_001526661 YP_001412712
Avi0937 Arad1125 NP_531421 YP_766543 YP_468407 NP_384946 NP_540458 YP_221170 YP_001369068
YP_673269 NP_107738 ZP_01228065 YP_783329 YP_578417 NP_769159 YP_001416847 YP_001523344 YP_001411987
Avi1834 Arad1967 NP_532630 YP_767374 YP_469193 NP_385458 NP_539670 YP_221941 YP_001370497 YP_032450 YP_674242 NP_102116 ZP_01225679 YP_782500 YP_576823 NP_772044 YP_001416577 YP_001525474 YP_001413997
Avi0440 Arad0658 NP_531064 YP_766000 YP_467923 NP_384513 NP_540891 YP_222786 YP_001369307 YP_031921 YP_676453 NP_106185 ZP_01228447 YP_779144 YP_575385 NP_767433 YP_001416714 YP_001522926 YP_001414874
Avi0208 Arad0444 NP_530964 YP_765875 YP_467813 NP_384391 NP_540922 YP_222755 YP_001369349 YP_031802 YP_673241 NP_105786 ZP_01228365 YP_779435 YP_575435 NP_767346 YP_001416833 YP_001527365 YP_001411500
Avi0353 Arad0545 NP_531009 YP_765942 YP_467869 NP_384443 NP_540686 YP_220946 YP_001368747 YP_032568 YP_676542 NP_105456 ZP_01228561 YP_779297 YP_575507 NP_767309 YP_001415254 YP_001527387 YP_001414841
Avi3170 Arad3176

YP_470511 NP_386448 NP_539406 YP_222205 YP_001370185 YP_032021 YP_674706 NP_103960 ZP_01226188 YP_780366 YP_578293 NP_774082 YP_001417446 YP_001526897 YP_001413534
Avi1069 Arad1256 NP_531481 YP_766646 YP_468504 NP_385023 NP_540371 YP_221254 YP_001369155 YP_032047 YP_673318 NP_107811 ZP_01228014 YP_779651 YP_578739 NP_768132 YP_001417493 YP_001523404 YP_001411961
Avi2080 Arad2688 NP_532300 YP_768284 YP_469888 NP_385963 NP_539892 YP_221724 YP_001370636
YP_674019 NP_102309 ZP_01225844 YP_780910 YP_576761 NP_770394 YP_001418105 YP_001525275 YP_001412367
Avi1913 Arad2613 NP_532550 YP_768215
NP_385898 NP_539708 YP_221903 YP_001370537 YP_032403 YP_673828 NP_101923 ZP_01228834 YP_780531 YP_576902 NP_772387 YP_001419447 YP_001524781 YP_001413846
Avi2508 Arad2512 NP_532168 YP_768144 YP_469736 NP_385499 NP_539006 YP_222620 YP_001369552
YP_673581 NP_102584 ZP_01227480 YP_781312 YP_577793 NP_770606 YP_001417439 YP_001526916 YP_001412797
Avi1614 Arad1755 NP_531865 YP_767226 YP_469041 NP_385317 NP_540105 YP_221513 YP_001371069 YP_032204 YP_673698 NP_108509 ZP_01227321 YP_781728 YP_577091 NP_771670 YP_001419157 YP_001524180 YP_001414175
Avi4188 Arad4395 NP_533351 YP_770102 YP_471417 NP_387336 NP_540770 YP_220868 YP_001368666 YP_031827 YP_675894 NP_105230 ZP_01229019 YP_779250 YP_575760 NP_767107 YP_001418734 YP_001527376 YP_001412681
Avi0947 Arad1143 NP_531337 YP_766553 YP_468417 NP_384955 NP_540452
YP_001369074 YP_032010 YP_673273 NP_107743 ZP_01228058 YP_783317 YP_578408 NP_769174 YP_001416281 YP_001523818 YP_001412005
Avi1826 Arad1962 NP_532636 YP_767370 YP_469189 NP_385454 NP_539666 YP_221947 YP_001370492 YP_032349 YP_674377 NP_102110 ZP_01225682 YP_782507 YP_576813 NP_772050 YP_001418250 YP_001523803 YP_001413994
Avi0169 Arad0173 NP_530796 YP_765729 YP_467668 NP_384345 NP_540882 YP_222795 YP_001369298 YP_031912 YP_676462 NP_106198 ZP_01228438 YP_779136 YP_575393 NP_767423 YP_001415208 YP_001522936 YP_001414883
Avi1835 Arad1968 NP_532629 YP_767375 YP_469194 NP_385459 NP_539671 YP_221940 YP_001370498 YP_032449 YP_674241 NP_102117 ZP_01225678 YP_782499 YP_576824 NP_772043 YP_001416578 YP_001525473 YP_001413998
Avi4196 Arad4403 NP_533358 YP_770108 YP_471425 NP_387343 NP_539049 YP_222581 YP_001369475 YP_032864 YP_675925 NP_105220 ZP_01229025 YP_779257 YP_575753 NP_767113 YP_001415328 YP_001526624 YP_001412690
Avi3159 Arad3162 NP_532874 YP_769038 YP_470507 NP_386438 NP_539413 YP_222197 YP_001370193 YP_032026 YP_674695 NP_103950 ZP_01226180 YP_779172 YP_575593 NP_767540 YP_001416657 YP_001523656 YP_001414383
Avi1786 Arad1924 NP_532019 YP_767685 YP_469386 NP_385424 NP_539981 YP_221641 YP_001370820
YP_674277 NP_102051 ZP_01225625 YP_781911 YP_577445 NP_770926 YP_001418382 YP_001524125 YP_001414556
Avi4141 Arad4351 NP_533313 YP_770058 YP_471373 NP_387181 NP_539090 YP_222541 YP_001369521 YP_032825 YP_675743 NP_105149 ZP_01228973 YP_779008 YP_575909 NP_767209 YP_001416014 YP_001523181 YP_001412618

Arad3232 NP_532935 YP_769086 YP_470556 NP_386479 NP_539370 YP_222240 YP_001370147
YP_674743 NP_104052 ZP_01226224 YP_780331 YP_578453 NP_769098 YP_001417122 YP_001526473 YP_001413488
Avi0446 Arad0666 NP_531082 YP_765992 YP_467917 NP_384519 NP_540702 YP_220931 YP_001368733 YP_031797 YP_676197 NP_104352
YP_779373 YP_575529 NP_767368 YP_001416934 YP_001523263
Avi1620 Arad1762 NP_531868 YP_767237 YP_469056 NP_385322 NP_540103 YP_221515 YP_001371067 YP_032206 YP_673700 NP_108511 ZP_01227323 YP_781730 YP_577093 NP_771668 YP_001419159 YP_001524182 YP_001414178
Avi4168 Arad4378 NP_533338 YP_770087 YP_471402 NP_387320 NP_540784 YP_220856 YP_001368650 YP_031748 YP_675400 NP_105248 ZP_01229006 YP_778979 YP_578814 NP_767165 YP_001415313 YP_001523668 YP_001412657
Avi1723 Arad1857 NP_531968 YP_767313 YP_469139 NP_385380 NP_540067 YP_221552 YP_001370958 YP_032227 YP_673592 NP_102964 ZP_01225747 YP_781449 YP_577464 NP_771549 YP_001419502 YP_001524592 YP_001414481
Avi1855 Arad1991 NP_532612 YP_767392 YP_469211 NP_385476 NP_539688 YP_221923 YP_001370515 YP_032432 YP_674224 NP_102134 ZP_01225664 YP_782482 YP_576841 NP_772026 YP_001419659 YP_001525456 YP_001414015
Avi3527 Arad3503 NP_533106 YP_769337 YP_470824 NP_386824 NP_539340 YP_222272 YP_001370114 YP_032546 YP_674770 NP_104064 ZP_01226947 YP_783175 YP_578561 NP_768840 YP_001418374 YP_001524116 YP_001413445
Avi1497 Arad1639 NP_531771 YP_767149 YP_468957 NP_385229 NP_540406 YP_221223 YP_001369119 YP_032122 YP_673543 NP_108067 ZP_01227389 YP_782253 YP_576964 NP_770699 YP_001417298 YP_001523452 YP_001414744
Avi1527 Arad1666 NP_531791 YP_767161 YP_468972 NP_385247 NP_540395 YP_221235 YP_001369130 YP_032132 YP_674328 NP_108083 ZP_01227400 YP_782220 YP_577606 NP_770722 YP_001418003 YP_001527228 YP_001414621
Avi1851 Arad1986 NP_532615 YP_767389 YP_469208 NP_385473 NP_539685 YP_221926 YP_001370512 YP_032435 YP_674227 NP_102131 ZP_01225667 YP_782485 YP_576838 NP_772029 YP_001419662 YP_001525459 YP_001414012
Avi4203 Arad4410 NP_533362 YP_770112 YP_471429 NP_387346 NP_539143 YP_222482 YP_001369626 YP_032818 YP_675877 NP_105262 ZP_01229029 YP_779266 YP_578767 NP_767121 YP_001416369 YP_001526867 YP_001412695
Avi0641 Arad4038 NP_531237 YP_766225 YP_468127 NP_384719 NP_540587 YP_221044 YP_001368884
YP_672758 NP_106962 ZP_01227805 YP_783383 YP_575646 NP_767898 YP_001416139 YP_001526063 YP_001411803
Avi0245 Arad0305 NP_530896 YP_765791 YP_467728 NP_384261 NP_540853 YP_220792 YP_001368573
YP_676614 NP_106149
YP_782674 YP_575731 NP_768066 YP_001417533 YP_001523049 YP_001411527

Arad4887 NP_533442 YP_770251 YP_471545 NP_387269 NP_539128 YP_222496 YP_001369607
YP_675990 NP_104982 ZP_01226739 YP_779207 YP_575872 NP_767071 YP_001416961 YP_001527052 YP_001412753
Avi1507 Arad1643 NP_531774 YP_767152 YP_468960 NP_385232 NP_540403 YP_221227 YP_001369122 YP_032125 YP_673547 NP_108070 ZP_01227392 YP_782250 YP_577543 NP_770702 YP_001417301 YP_001523449 YP_001414741
Avi3185 Arad3189 NP_532900 YP_769051 YP_470519 NP_386460 NP_539398 YP_222213 YP_001370176 YP_032016 YP_674714 NP_103973 ZP_01226196 YP_780367 YP_578300 NP_774081 YP_001417506 YP_001527063 YP_001413528
Avi0009 Arad0009 NP_530723 YP_765612 YP_467569 NP_384114 NP_540970 YP_222711 YP_001369397 YP_031819 YP_676021 NP_105388 ZP_01228893 YP_779314 YP_575478 NP_767282 YP_001416949 YP_001527516 YP_001412525
Avi0105 Arad0193 NP_530808 YP_765744 YP_467683 NP_384330 NP_540822 YP_220818 YP_001368578
YP_676619 NP_106154 ZP_01227691 YP_782679 YP_575721 NP_768061 YP_001417528 YP_001523054 YP_001411532
Avi2893 Arad2998 NP_532771 YP_768888 YP_470344 NP_386284 NP_539494 YP_222119 YP_001370287 YP_032500 YP_674567 NP_103117 ZP_01226108 YP_781029 YP_576562 NP_773244 YP_001416747 YP_001523017 YP_001413685
Avi2099 Arad2754 NP_532678 YP_768542 YP_470064 NP_386007 NP_539418 YP_222193 YP_001370198 YP_032534 YP_674689 NP_103929 ZP_01226172 YP_783096 YP_578150 NP_774071 YP_001417641 YP_001526043 YP_001413559
Avi1850 Arad1985 NP_532616 YP_767388 YP_469207 NP_385472 NP_539684 YP_221927 YP_001370511 YP_032436 YP_674228 NP_102130 ZP_01225668 YP_782486 YP_576837 NP_772030 YP_001416591 YP_001525460 YP_001414011
Avi1612 Arad1753 NP_531863
YP_469039 NP_385315 NP_540107 YP_221511 YP_001371071 YP_032202 YP_673696 NP_108507 ZP_01227319 YP_781726 YP_577089 NP_771672 YP_001419155 YP_001524178 YP_001414173
Avi3194 Arad3195 NP_532906 YP_769059 YP_470525 NP_386463 NP_539396 YP_222215 YP_001370174 YP_032013 YP_674716 NP_103975 ZP_01226198 YP_780369 YP_578298 NP_774079 YP_001417504 YP_001527066 YP_001413526
Avi2533 Arad2214 NP_532060 YP_767810 YP_469422 NP_385597 NP_539735 YP_221873 YP_001370570
YP_673938 NP_102421 ZP_01227498 YP_782305 YP_577700 NP_771774 YP_001418673 YP_001525237 YP_001414067
Avi2246 Arad2637 NP_532042 YP_768234 YP_469843 NP_385917 NP_539873 YP_221744 YP_001370660
YP_673973 NP_102518 ZP_01228820 YP_780785 YP_577874 NP_769699
YP_001524134 YP_001413401
Avi0543 Arad0779 NP_531135 YP_766163 YP_468067 NP_384626 NP_540535 YP_221091 YP_001368957
YP_672642 NP_106272 ZP_01226860 YP_783780 YP_575583 NP_767741 YP_001415385 YP_001526940 YP_001411688
Avi0395 Arad0609 NP_531032 YP_765985 YP_467910 NP_384480 NP_540689 YP_220943 YP_001368744 YP_031774 YP_676546 NP_105450 ZP_01228557 YP_779293 YP_575511 NP_767313 YP_001417435 YP_001527206 YP_001414836
Avi0103 Arad0195 NP_530809 YP_765745 YP_467684 NP_384329 NP_540821 YP_220819 YP_001368577 YP_031930 YP_676618 NP_106153 ZP_01227690 YP_782678 YP_575727 NP_768062 YP_001417529 YP_001523053 YP_001411531
Avi1817 Arad1954 NP_532642 YP_767363 YP_469183 NP_385448 NP_539660 YP_221953 YP_001370486 YP_032355 YP_674383 NP_102104
YP_782519 YP_576807 NP_772057 YP_001418244 YP_001523797 YP_001413988
Avi2233 Arad2457 NP_532304 YP_768095 YP_469692 NP_385546 NP_539766 YP_221840 YP_001370599 YP_032164 YP_674194 NP_102377 ZP_01227526 YP_781513 YP_577013 NP_771445 YP_001419078 YP_001525983 YP_001414419
Avi0352 Arad0543 NP_531008 YP_765941 YP_467868 NP_384442 NP_540687 YP_220945 YP_001368746 YP_032569 YP_676543 NP_105455 ZP_01228560 YP_779296 YP_575508 NP_767310 YP_001415255 YP_001527388 YP_001414840
Avi2900 Arad3006 NP_532777 YP_768894 YP_470350 NP_386290 NP_539488 YP_222125 YP_001370281 YP_032506 YP_674573 NP_103123 ZP_01226114 YP_781023 YP_576556 NP_773250 YP_001416754 YP_001527462 YP_001413679
Avi3524 Arad3499 NP_533102 YP_769333 YP_470820 NP_386821 NP_539344 YP_222266 YP_001370120 YP_032544 YP_674773 NP_104068 ZP_01226950 YP_779900 YP_576039 NP_773638 YP_001416214 YP_001523949 YP_001413456
Avi1915 Arad2610 NP_532548 YP_768212 YP_469822 NP_385896 NP_539711 YP_221900 YP_001370540 YP_032268 YP_673829 NP_101925 ZP_01228836 YP_780532 YP_576903 NP_772386 YP_001419448 YP_001524783 YP_001413847
Avi0956 Arad1155 NP_531344 YP_766563 YP_468428 NP_384961 NP_540446 YP_221184 YP_001369082 YP_032005 YP_673279 NP_107752 ZP_01228053 YP_783313 YP_578405 NP_769176 YP_001418215 YP_001523948 YP_001412008
Avi0018 Arad0022 NP_530731 YP_765623 YP_467579 NP_384132 NP_540932 YP_222748 YP_001369358 YP_031771 YP_673233 NP_105795 ZP_01228500 YP_779164 YP_575588 NP_767549 YP_001415218 YP_001527606 YP_001411290
Avi1592 Arad1734 NP_531850 YP_767209 YP_469027 NP_385300 NP_540119 YP_221497 YP_001371083 YP_032384 YP_673683 NP_108471 ZP_01227438 YP_782189 YP_577368 NP_770783 YP_001418027 YP_001526575 YP_001414564
Avi0039 Arad0052 NP_530752 YP_765644 YP_467600 NP_384155 NP_540956 YP_222724 YP_001369383 YP_031902 YP_676035 NP_105756 ZP_01228885 YP_779303 YP_575489 NP_767296 YP_001417187 YP_001527412 YP_001412506
Avi0005 Arad0003 NP_530719 YP_765608 YP_467565 NP_384110 NP_540974 YP_222707 YP_001369401 YP_031734 YP_676017 NP_105352 ZP_01228897 YP_779317 YP_575475 NP_767279 YP_001416732 YP_001522920 YP_001412530
Avi4292 Arad4926 NP_533488 YP_770284 YP_471577 NP_387428 NP_539151 YP_222474 YP_001369636 YP_032811 YP_675956 NP_105054 ZP_01228920 YP_778967 YP_575556 NP_767221 YP_001416634 YP_001527612 YP_001412596
Avi3226 Arad3216 NP_532923 YP_769076 YP_470543 NP_386468 NP_539380 YP_222230 YP_001370157 YP_032536 YP_674733 NP_104001 ZP_01226212 YP_779880 YP_578442 NP_769109 YP_001417845 YP_001526421 YP_001413508
Avi1532 Arad1672 NP_531796 YP_767165 YP_468976 NP_385251 NP_540388 YP_221240 YP_001369134 YP_032136 YP_674324 NP_108087 ZP_01227404 YP_782216 YP_577602 NP_770726 YP_001418021 YP_001527232 YP_001414617
Avi0405 Arad0620 NP_531039 YP_766028 YP_467952 NP_384488 NP_540707 YP_220926 YP_001368729 YP_031745 YP_676201 NP_104356 ZP_01228471 YP_779368 YP_575537 NP_767362 YP_001414981 YP_001526842 YP_001411473
Avi2876 Arad2980 NP_532757 YP_768872 YP_470330 NP_386270 NP_539506 YP_222106 YP_001370299 YP_032488 YP_674555 NP_103104 ZP_01226095 YP_781045 YP_576575 NP_773231 YP_001416664 YP_001523065 YP_001413698
Avi2211 Arad2472 NP_532429 YP_768112 YP_469704 NP_385531 NP_539832 YP_221780 YP_001370699 YP_032213 YP_673569 NP_102615 ZP_01225703 YP_781257 YP_576946 NP_772177 YP_001416541 YP_001523863 YP_001413933
Avi2521 Arad2223 NP_532067 YP_767818 YP_469429 NP_385604 NP_539743 YP_221865 YP_001370577 YP_032335 YP_673945 NP_102409 ZP_01227505 YP_781474 YP_576973 NP_771498 YP_001419314 YP_001524612 YP_001414456
Avi1854 Arad1990 NP_532613 YP_767391 YP_469210 NP_385475 NP_539687 YP_221924 YP_001370514 YP_032433 YP_674225 NP_102133 ZP_01225665 YP_782483 YP_576840 NP_772027 YP_001419660 YP_001525457 YP_001414014
Avi4261 Arad4658 NP_533381 YP_770173 YP_471502 NP_387355 NP_539205 YP_222417 YP_001369694 YP_032737 YP_675940 NP_104881 ZP_01226261 YP_781311 YP_577794 NP_770605 YP_001417498 YP_001523389 YP_001412176
Avi2656 Arad2139 NP_532248 YP_767655 YP_469354 NP_385647 NP_539991 YP_221631 YP_001370877 YP_032160 YP_674353 NP_102739 ZP_01227304 YP_781821 YP_577076 NP_771372 YP_001419190 YP_001525807
Avi0171 Arad0171 NP_530794 YP_765727 YP_467666 NP_384347 NP_540880 YP_222797 YP_001369296 YP_031910 YP_676464 NP_106200 ZP_01228436 YP_779134 YP_575395 NP_767421 YP_001415206 YP_001522938 YP_001414885
Avi0445 Arad0665 NP_531069 YP_765995 YP_467918 NP_384518 NP_540886 YP_222791 YP_001369302 YP_031916 YP_676457 NP_106193 ZP_01228442 YP_779140 YP_575389 NP_767428 YP_001416719 YP_001522931 YP_001414879
Avi4280 Arad4878 NP_533444 YP_770245 YP_471539 NP_387267 NP_539126 YP_222498 YP_001369605 YP_031860 YP_675992 NP_104986 ZP_01226342 YP_779205 YP_575870 NP_767069 YP_001416959 YP_001527054 YP_001412755
Avi2204 Arad2478 NP_532434 YP_768117 YP_469711 NP_385524 NP_539825 YP_221786 YP_001370705
YP_673564 NP_102623 ZP_01225709 YP_781252 YP_576928 NP_772190 YP_001416549 YP_001526583 YP_001413927
Avi0640 Arad4037 NP_531236 YP_766226 YP_468128 NP_384720 NP_540588 YP_221043 YP_001368883 YP_032672 YP_672757 NP_106961
YP_782652 YP_575750 NP_768086 YP_001418091 YP_001525281 YP_001411806
Avi2471 Arad2632 NP_532046 YP_768230 YP_469839 NP_385913 NP_539869 YP_221748 YP_001370664
YP_673977 NP_102509 ZP_01228824 YP_783218 YP_578580 NP_773894 YP_001418666 YP_001524575
Avi1314 Arad1480 NP_531620 YP_766993 YP_468787 NP_385110 NP_540272 YP_221339 YP_001371222
YP_673444 NP_107926 ZP_01227022 YP_780802 YP_577810 NP_769714 YP_001416313 YP_001524011
Avi1784 Arad1919 NP_532017 YP_767683 YP_469383 NP_385422 NP_539983
YP_001370822 YP_032360 YP_674279 NP_102048 ZP_01225627 YP_781552 YP_577083 NP_770919 YP_001418380 YP_001524124 YP_001414559
Avi2561 Arad2240 NP_532085 YP_767830 YP_469441 NP_385716 NP_539757 YP_221850 YP_001370590 YP_032265 YP_674202 NP_102395 ZP_01227518 YP_781489 YP_577004 NP_771466 YP_001419249 YP_001525117 YP_001414441
Avi2547 Arad2204 NP_532261 YP_767801 YP_469414 NP_385587 NP_540123 YP_221493 YP_001371087 YP_032388 YP_673679

YP_781229 YP_577825 NP_772230 YP_001418118 YP_001526460 YP_001413870
Avi0110 Arad0186 NP_530805 YP_765739 YP_467678 NP_384336 NP_540825 YP_220815 YP_001368581 YP_031928 YP_676589 NP_106158 ZP_01227695 YP_783712 YP_575812 NP_774756 YP_001417069 YP_001523058 YP_001411535
Avi1519 Arad1657 NP_531787 YP_767158 YP_468969 NP_385243 NP_540398 YP_221232 YP_001369128 YP_032129 YP_674475 NP_108079
YP_782223 YP_577608 NP_770718 YP_001418006 YP_001527223 YP_001414623
Avi0050 Arad0038 NP_530742 YP_765634 YP_467590 NP_384144 NP_540944 YP_222734 YP_001369372 YP_031755 YP_676111 NP_105811 ZP_01228488 YP_779404 YP_575414 NP_767397 YP_001418182 YP_001523626 YP_001411398
Avi2511 Arad2234 NP_532076 YP_767827 YP_469438 NP_385613 NP_539752 YP_221855 YP_001370586 YP_032327 YP_673954 NP_102399 ZP_01227514 YP_781484 YP_576983 NP_771487 YP_001419304 YP_001524622 YP_001414445
Avi3122 Arad3135 NP_532851 YP_768999 YP_470460 NP_385682 NP_539439 YP_222171 YP_001370224 YP_032525 YP_674652 NP_103843 ZP_01225946 YP_782866 YP_578103 NP_774017 YP_001417647 YP_001524061 YP_001413584
Avi4288 Arad4870 NP_533450 YP_770238 YP_471532 NP_387261 NP_539119 YP_222505 YP_001369599 YP_031848 YP_675997 NP_104992 ZP_01226337 YP_779495 YP_575864 NP_767060 YP_001417043 YP_001527010 YP_001412760
Avi2857 Arad2968 NP_532747 YP_768866 YP_470323 NP_386261 NP_539509 YP_222103 YP_001370304 YP_032486 YP_674551 NP_103098 ZP_01226084 YP_781049 YP_577985 NP_773228 YP_001416329 YP_001527394 YP_001413701
Avi2808 Arad2901 NP_532715 YP_768830 YP_470289 NP_386224 NP_539533 YP_222078 YP_001370346 YP_032473 YP_674302 NP_103034 ZP_01227118 YP_781110 YP_577962 NP_773144 YP_001416561 YP_001525491 YP_001413729
Avi1588 Arad1732 NP_531848 YP_767207 YP_469025 NP_385297 NP_540120 YP_221496 YP_001371084 YP_032385 YP_673682 NP_108468 ZP_01227437 YP_782191 YP_577369 NP_770775 YP_001418025 YP_001526577 YP_001414585
Avi4181 Arad4386 NP_533346 YP_770096 YP_471411 NP_387327 NP_540777 YP_220863 YP_001368659
YP_675888 NP_105237 ZP_01229013 YP_779244 YP_575900 NP_767101 YP_001416659 YP_001526679 YP_001412671
Avi0062 Arad0073 NP_530764 YP_765660 YP_467614 NP_384170 NP_540727 YP_220909 YP_001368711
YP_676572 NP_105998 ZP_01228507 YP_779170 YP_575592 NP_767543 YP_001415222 YP_001527567 YP_001411301
Avi1681 Arad1810 NP_531939 YP_767276 YP_469099 NP_385348 NP_540086 YP_221533 YP_001371038 YP_032305 YP_673724 NP_108551 ZP_01225965 YP_781775 YP_577704 NP_771602 YP_001419223 YP_001525107 YP_001414202
Avi4380 Arad4934 NP_533412 YP_770293 YP_471585 NP_387436 NP_539159 YP_222466 YP_001369643 YP_032760 YP_675745 NP_105035 ZP_01228912 YP_779331 YP_575457 NP_767263 YP_001415193 YP_001523193 YP_001412562
Avi0209 Arad0445 NP_530965 YP_765876 YP_467814 NP_384392 NP_540921 YP_222756 YP_001369348 YP_031803 YP_673242 NP_105784 ZP_01228364 YP_779432 YP_575434 NP_767345 YP_001416832 YP_001527366 YP_001411501
Avi2665 Arad2130 NP_532387 YP_767647 YP_469346 NP_385638 NP_539999 YP_221623 YP_001370885 YP_032155 YP_674362 NP_102749 ZP_01227296 YP_781617 YP_577065 NP_771388 YP_001419282 YP_001524655 YP_001414294
Avi4332 Arad4692 NP_533388 YP_770194 YP_471480 NP_387377 NP_539187 YP_222440 YP_001369672 YP_032747 YP_675873 NP_104821 ZP_01228202 YP_779123 YP_575968 NP_767576 YP_001416791 YP_001527497
Avi1941 Arad2585 NP_532530 YP_768196 YP_469793 NP_385885 NP_540044 YP_221577 YP_001370932 YP_032379 YP_673838 NP_101938 ZP_01228843 YP_780542 YP_576915 NP_772359 YP_001418969 YP_001525147 YP_001413851
Avi1863 Arad2000 NP_532607 YP_767398 YP_469217 NP_385482 NP_539694 YP_221917 YP_001370521 YP_032426 YP_674218 NP_102140 ZP_01225659 YP_782476 YP_576847 NP_772020 YP_001419653 YP_001525450 YP_001414021
Avi4137 Arad4348 NP_533310 YP_770016 YP_471370 NP_387178 NP_539077 YP_222553 YP_001369501 YP_032799 YP_675783 NP_105177 ZP_01229036 YP_779449 YP_578804 NP_767152 YP_001416868 YP_001526659 YP_001412710
Avi0496 Arad0764 NP_531123 YP_766150 YP_468054 NP_384614 NP_540541 YP_221085 YP_001368941
YP_672582 NP_106265 ZP_01226846 YP_783791 YP_575982 NP_767730 YP_001415112 YP_001526954 YP_001411673
Avi2378 Arad2375 NP_532451 YP_767984 YP_469615 NP_385744 NP_539894 YP_221722 YP_001370634
YP_674107 NP_102160 ZP_01227556 YP_781425 YP_577484 NP_771587 YP_001418472 YP_001524519 YP_001414498
Avi0051 Arad0037 NP_530741 YP_765633 YP_467589 NP_384143 NP_540943 YP_222735 YP_001369371 YP_031754 YP_676112 NP_105810 ZP_01228489 YP_779403 YP_575415 NP_767396 YP_001418183 YP_001523627
Avi2081 Arad2687 NP_532299 YP_768283 YP_469887 NP_385962 NP_539891 YP_221726 YP_001370637 YP_032319 YP_674020 NP_102308 ZP_01225843 YP_780911 YP_576762 NP_770395 YP_001418107 YP_001525274 YP_001412372
Avi1840 Arad1971 NP_532626 YP_767378 YP_469197 NP_385462 NP_539674 YP_221937 YP_001370501 YP_032446 YP_674238 NP_102120 ZP_01225675 YP_782496 YP_576827 NP_772040 YP_001416581 YP_001525470 YP_001414001
Avi1575 Arad1725 NP_531838 YP_767200 YP_469018 NP_385290 NP_540157 YP_221465 YP_001371118 YP_032367 YP_674524 NP_108163 ZP_01227431 YP_782197 YP_577375 NP_770765 YP_001417223 YP_001527077 YP_001414592
Avi4108 Arad4308 NP_533289 YP_769979 YP_471345 NP_387142 NP_539167 YP_222459 YP_001369652 YP_032754 YP_675753 NP_105025 ZP_01226748 YP_779221 YP_575882 NP_767082 YP_001416979 YP_001527043 YP_001412740
Avi1534 Arad1673 NP_531797 YP_767166 YP_468977 NP_385252 NP_540387 YP_221241 YP_001369135
YP_674323 NP_108088 ZP_01227405 YP_782215 YP_577601 NP_770727 YP_001418022 YP_001527233 YP_001414616
Avi2160 Arad2413 NP_532184 YP_768056 YP_469665 NP_385705 NP_539902 YP_221714 YP_001370626 YP_032258 YP_674145 NP_102217 ZP_01225595 YP_781786 YP_577265 NP_771154 YP_001419267 YP_001525180 YP_001414379
Avi1859 Arad1995 NP_532609 YP_767395 YP_469214 NP_385479 NP_539691 YP_221920 YP_001370518 YP_032429 YP_674221 NP_102137 ZP_01225661 YP_782479 YP_576844 NP_772023 YP_001419656 YP_001525453 YP_001414018
Avi4342 Arad4685 NP_530821 YP_770188 YP_471486 NP_387370 NP_539190 YP_222437 YP_001369677 YP_032745 YP_675962 NP_104812
YP_779114 YP_575973 NP_767588 YP_001417998 YP_001523226 YP_001412835
Avi2654 Arad2142 NP_532353 YP_767657 YP_469356 NP_385649 NP_539990 YP_221632 YP_001370876
YP_674351 NP_102736 ZP_01227306 YP_781820 YP_577078 NP_771367 YP_001419192 YP_001525805 YP_001414305
Avi2891 Arad2996 NP_532769 YP_768886 YP_470342 NP_386282 NP_539496 YP_222117 YP_001370289 YP_032498 YP_674565 NP_103115 ZP_01226106 YP_781031 YP_576564 NP_773242 YP_001416097 YP_001527471 YP_001413687
Avi0976 Arad1174 NP_531424 YP_766572 YP_468437 NP_384974 NP_540445 YP_221185 YP_001369084 YP_032029 YP_673280 NP_107756 ZP_01228051 YP_783284 YP_579138 NP_769210 YP_001418151 YP_001523323 YP_001412054
Avi2659 Arad2136 NP_532251 YP_767652 YP_469351 NP_385644 NP_539994 YP_221628 YP_001370880 YP_032158 YP_674356 NP_102742 ZP_01227301 YP_781825 YP_577072 NP_771376 YP_001419186 YP_001525811 YP_001414299
Avi0246 Arad0306 NP_530897 YP_765792 YP_467729 NP_384260 NP_540854 YP_220791 YP_001368572
YP_676613 NP_106148 ZP_01227686 YP_782673 YP_575732 NP_768067 YP_001417534 YP_001523048 YP_001411526
Avi0585 Arad0790 NP_531188 YP_766180 YP_468084 NP_384656 NP_540527 YP_221099 YP_001368965
YP_672663 NP_106298 ZP_01228322 YP_779657 YP_575906 NP_767779 YP_001416373 YP_001523303 YP_001411716
Avi1847 Arad1980 NP_532619 YP_767385 YP_469204 NP_385469 NP_539681 YP_221930 YP_001370508 YP_032439 YP_674231 NP_102127 ZP_01225670 YP_782489 YP_576834 NP_772033 YP_001416588 YP_001525463 YP_001414008
Avi0942 Arad1132 NP_531333 YP_766548 YP_468412 NP_384951 NP_540448 YP_221182 YP_001369080 YP_032007 YP_673277 NP_107749 ZP_01228061 YP_783324 YP_578412 NP_769165 YP_001416287 YP_001523827 YP_001412000
Avi3115 Arad3132 NP_532848 YP_768996 YP_470458 NP_385684 NP_539442 YP_222168 YP_001370226
YP_674644 NP_103826 ZP_01228054 YP_783334 YP_578419 NP_769150 YP_001416171 YP_001525315
Avi1739 Arad1870 NP_531978 YP_767323 YP_469149 NP_385392 NP_540057 YP_221564 YP_001370948 YP_032235 YP_673602 NP_102953 ZP_01225736 YP_781462 YP_577449 NP_771517 YP_001419341 YP_001524602 YP_001414468
Avi1810 Arad1946 NP_532670 YP_767360 YP_469180 NP_385444 NP_539658 YP_221956 YP_001370484 YP_032357 YP_673646 NP_102094 ZP_01225693 YP_782592 YP_577752 NP_772139 YP_001418240 YP_001523794 YP_001413986
Avi3529 Arad3506 NP_533110 YP_769339 YP_470826 NP_386826 NP_539341 YP_222271 YP_001370116 YP_032547 YP_674768 NP_104062 ZP_01226945 YP_783189 YP_578567 NP_768831 YP_001418373 YP_001523999 YP_001413444
Avi0020 Arad0026 NP_530733 YP_765625 YP_467581 NP_384134 NP_540935 YP_222745 YP_001369361
YP_673231 NP_105798 ZP_01228498 YP_779393 YP_575424 NP_767385 YP_001416595 YP_001523934 YP_001411423
Avi4279 Arad4880 NP_533443 YP_770246 YP_471540 NP_387268 NP_539127 YP_222497 YP_001369606 YP_031861 YP_675991 NP_104985 ZP_01226343 YP_779206 YP_575871 NP_767070 YP_001416960 YP_001527053 YP_001412754
Avi2286 Arad2184 NP_532485 YP_767700 YP_469400 NP_385824 NP_539648 YP_221967 YP_001370468 YP_032275 YP_674292 NP_102024 ZP_01227452 YP_781835 YP_577398 NP_771050 YP_001419052 YP_001524852 YP_001414238
Avi1781 Arad1914 NP_532014 YP_767680 YP_469380 NP_385420 NP_539985 YP_221637 YP_001370824 YP_032361 YP_674280 NP_102042 ZP_01225629 YP_782268 YP_577523 NP_771727 YP_001418809 YP_001525763 YP_001414108
Avi2809 Arad2903 NP_532716 YP_768831 YP_470290 NP_386225 NP_539532 YP_222079 YP_001370345
YP_674303 NP_103035 ZP_01227117 YP_781109 YP_577963 NP_773145 YP_001416562 YP_001525490 YP_001413728
Avi1546 Arad1688 NP_531808 YP_767176 YP_468987 NP_385262 NP_540177 YP_221445 YP_001371141 YP_032144 YP_674314 NP_108098 ZP_01227414 YP_782203 YP_577590 NP_770749 YP_001416364 YP_001523456 YP_001414597
Avi2896 Arad3002 NP_532774 YP_768891 YP_470347 NP_386287 NP_539491 YP_222122 YP_001370284 YP_032503 YP_674570 NP_103120 ZP_01226111 YP_781026 YP_576559 NP_773247 YP_001416751 YP_001527459 YP_001413682
Avi2278 Arad2161 NP_532275 YP_767694 YP_469395 NP_385829 NP_539641 YP_221974 YP_001370461
YP_674481 NP_102630 ZP_01227077 YP_781855 YP_577562 NP_771001 YP_001418408 YP_001524763 YP_001414209
Avi1372 Arad1502 NP_531679 YP_767047 YP_468828 NP_385130 NP_540244 YP_221369 YP_001371205 YP_032080 YP_673466 NP_107961 ZP_01228736 YP_780868 YP_576730 NP_769773 YP_001418405 YP_001524055 YP_001412226
Avi1849 Arad1983 NP_532617 YP_767387 YP_469206 NP_385471 NP_539683 YP_221928 YP_001370510 YP_032437 YP_674229 NP_102129
YP_782487 YP_576836 NP_772031 YP_001416590 YP_001525461 YP_001414010
Avi0406 Arad0622 NP_531040 YP_766027 YP_467951 NP_384489 NP_540708 YP_220925
YP_031744 YP_676202 NP_104357 ZP_01228470 YP_779367 YP_575538 NP_767361
YP_001526843 YP_001411474
Avi2664 Arad2132 NP_532386 YP_767648 YP_469347 NP_385639 NP_539998 YP_221624 YP_001370884
YP_674361 NP_102748 ZP_01227297 YP_781620 YP_577066 NP_771386 YP_001419281 YP_001524135 YP_001414295
Avi1555 Arad1710 NP_531824 YP_767189 YP_469007 NP_385275 NP_540170 YP_221452 YP_001371133
YP_674535 NP_108127 ZP_01227420 YP_779862 YP_578340 NP_774112 YP_001417246 YP_001526884 YP_001413545
Avi2887 Arad2991 NP_532764 YP_768880 YP_470338 NP_386277 NP_539499 YP_222114 YP_001370292 YP_032495 YP_674562 NP_103112 ZP_01226103 YP_781037

YP_001415240 YP_001527477 YP_001413690
Avi4352 Arad4671 NP_533430 YP_770179 YP_471496 NP_387363 NP_539196 YP_222429 YP_001369683 YP_032744 YP_675915 NP_104870 ZP_01228183 YP_779065 YP_575857 NP_766796 YP_001415103 YP_001526959 YP_001412970
Avi1487 Arad1637 NP_531770 YP_767147 YP_468955 NP_385217 NP_540189 YP_221430
YP_032117 YP_673527 NP_108040 ZP_01228784 YP_780922 YP_576770 NP_770430 YP_001419593 YP_001524700 YP_001413930
Avi0997 Arad1198 NP_531445 YP_766585 YP_468451 NP_384986 NP_540415 YP_221214 YP_001369107 YP_032040 YP_673300 NP_107784 ZP_01228035 YP_780001 YP_576117 NP_769291 YP_001419609 YP_001526027 YP_001412061
Avi0021 Arad0028 NP_530734 YP_765626 YP_467582 NP_384135 NP_540936 YP_222743 YP_001369363
YP_673229 NP_105799 ZP_01228497 YP_779394 YP_575423 NP_767386 YP_001416597 YP_001523936 YP_001411422
Avi0001 Arad0000 NP_530716 YP_765605 YP_467562 NP_384107 NP_540977 YP_222704 YP_001369404 YP_031731 YP_676014 NP_105349
YP_779319 YP_575473 NP_767277 YP_001416729 YP_001522917 YP_001412533
Avi2879 Arad2981 NP_532758 YP_768874 YP_470332 NP_386271 NP_539505 YP_222107 YP_001370298 YP_032489 YP_674556 NP_103105 ZP_01226097 YP_781043 YP_576574 NP_773233 YP_001415246 YP_001527484 YP_001413697
Avi1465 Arad1613 NP_531753 YP_767132 YP_468936 NP_385213 NP_540194 YP_221424 YP_001371157 YP_032116 YP_673524 NP_108036 ZP_01228780 YP_783290 YP_579145 NP_769201 YP_001416382 YP_001523315
Avi2890 Arad2995 NP_532768 YP_768885 YP_470341 NP_386281 NP_539497 YP_222116 YP_001370290 YP_032497 YP_674564 NP_103114 ZP_01226105 YP_781032 YP_576565 NP_773241 YP_001416098 YP_001527472 YP_001413688
Avi4208 Arad4416 NP_533366 YP_770116 YP_471433 NP_387350 NP_539067 YP_222561 YP_001369494 YP_032801 YP_675980 NP_105193 ZP_01229033 YP_779269 YP_578770 NP_767126 YP_001417410 YP_001526870 YP_001412698
Avi1906 Arad2573 NP_532523 YP_768190 YP_469785 NP_385878 NP_540039 YP_221582 YP_001370925 YP_032376 YP_673842 NP_101947 ZP_01228848 YP_780536 YP_576912 NP_772369 YP_001418972 YP_001525144 YP_001413854
Avi1618 Arad1760 NP_531867 YP_767236 YP_469055 NP_385321 NP_540104 YP_221514 YP_001371068 YP_032205 YP_673699 NP_108510 ZP_01227322 YP_781729 YP_577092 NP_771669 YP_001419158 YP_001524181 YP_001414177
Avi2248 Arad2634 NP_532044 YP_768232 YP_469841 NP_385915 NP_539871 YP_221746 YP_001370662
YP_673975 NP_102516 ZP_01228821 YP_780783 YP_577876 NP_769697 YP_001417391 YP_001524133
Avi2606 Arad2056 NP_532412 YP_767552 YP_469278 NP_385742 NP_539854 YP_221762 YP_001370680
YP_673901 NP_102004 ZP_01225570 YP_781219 YP_577833 NP_772251 YP_001418427 YP_001524735 YP_001413866
Avi2687 Arad2107 NP_532405 YP_767631 YP_469329 NP_385619 NP_539947 YP_221676 YP_001370789 YP_032460 YP_674129 NP_102770 ZP_01227280 YP_781664 YP_577061 NP_771112 YP_001419112 YP_001525734 YP_001414267
Avi3536 Arad3512 NP_533115 YP_769344 YP_470831 NP_386831 NP_539294 YP_222320 YP_001369783 YP_031974 YP_675683 NP_104781 ZP_01226901 YP_779753 YP_578087 NP_773976 YP_001416886 YP_001527170 YP_001413435
Avi3163 Arad3167 NP_532878 YP_769035 YP_470505 NP_386442 NP_539411 YP_222200 YP_001370190
YP_674698 NP_103953 ZP_01226182 YP_780355 YP_578334 NP_774100 YP_001417456 YP_001526889 YP_001413541
Avi2263 Arad2518 NP_532163 YP_768149 YP_469741 NP_385493 NP_539897 YP_221719 YP_001370631 YP_032414 YP_674207
ZP_01225646 YP_782455 YP_576857 NP_772004 YP_001419637 YP_001525435 YP_001414035
Avi1844 Arad1977 NP_532622 YP_767382 YP_469201 NP_385466 NP_539678 YP_221933 YP_001370505 YP_032442 YP_674234 NP_102124
YP_782492 YP_576831 NP_772036 YP_001416585 YP_001525466 YP_001414005
Avi2671 Arad2122 NP_532392 YP_767642 YP_469341 NP_385632 NP_540003 YP_221618 YP_001370890
YP_674368 NP_102754
YP_781611 YP_577035 NP_771393 YP_001419288 YP_001524649 YP_001414289
Avi4227 Arad4444 NP_533428 YP_770124 YP_471440 NP_387309 NP_538984 YP_222646 YP_001369515 YP_032826 YP_675960 NP_105156 ZP_01228970 YP_779333 YP_575455 NP_767260 YP_001416673 YP_001523006 YP_001412566
Avi3190 Arad3192 NP_532903 YP_769054 YP_470522 NP_386461 NP_539397 YP_222214 YP_001370175 YP_032015 YP_674715 NP_103974 ZP_01226197 YP_780368 YP_578299 NP_774080 YP_001417505 YP_001527064 YP_001413527
Avi0032 Arad0061 NP_530759 YP_765653 YP_467608 NP_384162 NP_540964 YP_222717 YP_001369390 YP_031904 YP_676028 NP_105747 ZP_01228880 YP_779310 YP_575482 NP_767289 YP_001417195 YP_001523138 YP_001412516
Avi1095 Arad1283 NP_531501 YP_766694 YP_468538 NP_385037 NP_540356 YP_221271 YP_001369173
YP_673333 NP_107823
YP_783347 YP_578425 NP_769136 YP_001416882 YP_001527174 YP_001411979
Avi1869 Arad2007 NP_532602 YP_767403 YP_469222 NP_385487 NP_539699 YP_221912 YP_001370526 YP_032421 YP_674213 NP_102145 ZP_01225654 YP_782471 YP_576852 NP_772015 YP_001419648 YP_001525445 YP_001414026
Avi2445 Arad2387 NP_532365 YP_767993 YP_469624 NP_385688 NP_539803 YP_221803 YP_001370725 YP_032407 YP_673963 NP_102476 ZP_01227562 YP_781683 YP_577040 NP_771333 YP_001418669 YP_001525242 YP_001414314
Avi2824 Arad2936
YP_768838 YP_470296 NP_386239 NP_539520 YP_222090 YP_001370318 YP_032481 YP_674540 NP_103054 ZP_01227109 YP_781069 YP_577970 NP_773158 YP_001416323 YP_001527401
Avi0108 Arad0188 NP_530807 YP_765741 YP_467680 NP_384334 NP_540823 YP_220817 YP_001368579
YP_675852 NP_106156 ZP_01227692 YP_783714
NP_774763 YP_001417526 YP_001523056 YP_001411534

Arad3178 NP_532887 YP_769044 YP_470513 NP_386450 NP_539404 YP_222207 YP_001370183 YP_032019 YP_674708 NP_103963 ZP_01226190 YP_780364 YP_578291 NP_774085 YP_001417448 YP_001526899 YP_001413532
Avi0390 Arad0600 NP_531029 YP_765981 YP_467906 NP_384473 NP_540861 YP_222814 YP_001368562 YP_031829 YP_676634 NP_106218
YP_783819 YP_579165 NP_767472 YP_001416592 YP_001523931 YP_001411281
Avi0424 Arad0642 NP_531052 YP_766012 YP_467936 NP_384502 NP_540721 YP_220915 YP_001368717
YP_676565 NP_106008 ZP_01228457 YP_779199 YP_575586 NP_767556 YP_001415199 YP_001523254 YP_001414857
Avi1475 Arad1628 NP_531763 YP_767140 YP_468947 NP_385224 NP_540412 YP_221217 YP_001369111
YP_673533 NP_108050 ZP_01228793 YP_780930 YP_576773 NP_770434 YP_001419061 YP_001524421 YP_001412389
Avi1886 Arad2551 NP_532510 YP_768175 YP_469769 NP_385847 NP_539966 YP_221658 YP_001370807 YP_032245 YP_674346 NP_101898 ZP_01225612 YP_781891 YP_577586 NP_770964 YP_001419073 YP_001526538 YP_001414532
Avi1324 Arad1487 NP_531630 YP_767000 YP_468794 NP_385117 NP_539451 YP_222161 YP_001370236
YP_674628 NP_103763 ZP_01227028 YP_780809 YP_576686 NP_769743 YP_001417308 YP_001524016 YP_001412178
Avi0047 Arad0042 NP_530746 YP_765637 YP_467593 NP_384147 NP_540949 YP_222730 YP_001369376 YP_031779 YP_676108 NP_105814 ZP_01228484 YP_779760 YP_575790 NP_774787 YP_001417745 YP_001526984 YP_001411394
Avi1038 Arad1226 NP_531466 YP_766631 YP_468489 NP_385009 NP_540384 YP_221244 YP_001369140 YP_032043 YP_673305 NP_107794 ZP_01228025 YP_783649 YP_575614 NP_767809 YP_001419526 YP_001525877
Avi3173 Arad3179 NP_532888 YP_769045 YP_470514 NP_386451 NP_539403 YP_222208 YP_001370182 YP_032018 YP_674709 NP_103964 ZP_01226191 YP_780363 YP_578290 NP_774086 YP_001417449 YP_001526900 YP_001413531
Avi1127 Arad1295 NP_531507 YP_766703 YP_468551 NP_385042 NP_540349 YP_221277 YP_001369246
YP_673340 NP_107838 ZP_01227997 YP_783259 YP_576096 NP_769257 YP_001417369 YP_001524398 YP_001412081
Avi0438 Arad0657 NP_531063 YP_766001 YP_467924 NP_384512 NP_540892 YP_222785 YP_001369308 YP_031922 YP_676452 NP_106184 ZP_01228448 YP_779145 YP_575384 NP_767434 YP_001416713 YP_001522925 YP_001414873
Avi0545 Arad0783 NP_531138 YP_766165 YP_468070 NP_384629 NP_540533 YP_221093 YP_001368959 YP_031961 YP_672667 NP_106275 ZP_01226863 YP_783775 YP_575578 NP_767746 YP_001415387 YP_001526936 YP_001411690
Avi2524 Arad2222 NP_532066 YP_767817 YP_469428 NP_385603 NP_539742 YP_221866 YP_001370576 YP_032336 YP_673944 NP_102410 ZP_01227504 YP_781473 YP_576972 NP_771499 YP_001419315 YP_001524611 YP_001414457
Avi1500 Arad1642 NP_531773 YP_767151 YP_468959 NP_385231 NP_540404 YP_221226 YP_001369121 YP_032124 YP_673546 NP_108069 ZP_01227391 YP_782251 YP_577544 NP_770701 YP_001417300 YP_001523450 YP_001414742
Avi2450 Arad2393 NP_532362 YP_767996 YP_469627 NP_385691 NP_539806 YP_221800 YP_001370722
YP_673966 NP_102472 ZP_01227565 YP_781687 YP_577044 NP_771329 YP_001419148 YP_001525224 YP_001414317
Avi2661 Arad2135 NP_532252 YP_767651 YP_469350 NP_385643 NP_539995 YP_221627 YP_001370881
YP_674358 NP_102743 ZP_01227300 YP_781826 YP_577071 NP_771377 YP_001419125 YP_001524544 YP_001414298
Avi1072 Arad1260 NP_531484 YP_766670 YP_468514 NP_385024 NP_540370 YP_221255 YP_001369156 YP_032048 YP_673322 NP_107812 ZP_01228012 YP_779607 YP_578738 NP_768142 YP_001417309 YP_001523405
Avi0166 Arad0176 NP_530798 YP_765731 YP_467670 NP_384343 NP_540884 YP_222793 YP_001369300 YP_031914 YP_676460 NP_106196 ZP_01228440 YP_779138 YP_575391 NP_767425 YP_001415210 YP_001522934 YP_001414881
Avi1799 Arad1938 NP_532032 YP_767348 YP_469174 NP_385437 NP_539971 YP_221652 YP_001370810 YP_032244 YP_674267 NP_102062 ZP_01225615 YP_781893 YP_577099 NP_770948 YP_001419548 YP_001526540 YP_001414537
Avi1848 Arad1982 NP_532618 YP_767386 YP_469205 NP_385470 NP_539682 YP_221929 YP_001370509 YP_032438 YP_674230 NP_102128 ZP_01225669 YP_782488 YP_576835 NP_772032 YP_001416589 YP_001525462 YP_001414009
Avi0206 Arad0441 NP_530962 YP_765874 YP_467812 NP_384390 NP_540924 YP_222753 YP_001369351 YP_031801 YP_673239 NP_105787 ZP_01228366 YP_779436 YP_575436 NP_767347 YP_001416834 YP_001527364 YP_001411499
Avi3530 Arad3507 NP_533111 YP_769340 YP_470827 NP_386827 NP_539342 YP_222269 YP_001370117 YP_032548 YP_674767 NP_104061 ZP_01226944 YP_783192 YP_578570 NP_768829 YP_001418371 YP_001523997 YP_001413439
Avi4112 Arad4315 NP_533292 YP_769982 YP_471348 NP_387145 NP_539164 YP_222462 YP_001369649 YP_032756 YP_675750 NP_105030 ZP_01226752 YP_779225 YP_575885 NP_767085 YP_001416954 YP_001527060 YP_001412737
Avi1580 Arad1728 NP_531841 YP_767203 YP_469021 NP_385293 NP_540122 YP_221494 YP_001371086 YP_032387 YP_673680 NP_108316 ZP_01227435 YP_782194 YP_577372 NP_770762 YP_001418014 YP_001526582 YP_001414587
Avi1856 Arad1992 NP_532611 YP_767393 YP_469212 NP_385477 NP_539689 YP_221922 YP_001370516 YP_032431 YP_674223 NP_102135 ZP_01225663 YP_782481 YP_576842 NP_772025 YP_001419658 YP_001525455 YP_001414016
Avi4191 Arad4397 NP_533353 YP_770104 YP_471420 NP_387338 NP_540768 YP_220870 YP_001368668 YP_031825 YP_675896 NP_108446 ZP_01229021 YP_779252 YP_575762 NP_767109 YP_001419009 YP_001527373 YP_001412683
Avi1670 Arad1800 NP_531935 YP_767270 YP_469094 NP_385345 NP_540089 YP_221530 YP_001371044 YP_032199 YP_673721 NP_108545 ZP_01225971 YP_781766 YP_577710 NP_771608 YP_001419216 YP_001525100 YP_001414191
Avi1118 Arad1345 NP_531516 YP_766867 YP_468666 NP_385050 NP_540682 YP_220950 YP_001368751
YP_676524 NP_104381 ZP_01228956 YP_780695 YP_578750 NP_768121 YP_001416300 YP_001523839 YP_001414042
Avi2478 Arad2148 NP_532349 YP_767660 YP_469361 NP_385652 NP_539986 YP_221636 YP_001370825 YP_032362 YP_674349 NP_102729 ZP_01227307 YP_781427 YP_577482 NP_771585 YP_001418475 YP_001524523 YP_001414497
Avi4282 Arad4875 NP_533446 YP_770243 YP_471537 NP_387265 NP_539124 YP_222500 YP_001369603 YP_031858 YP_675994 NP_104988 ZP_01226340 YP_779489 YP_575867 NP_767065 YP_001416956 YP_001527057 YP_001412757
Avi2109 Arad2243 NP_532116 YP_767833 YP_469444 NP_385549 NP_539768 YP_221838 YP_001370601 YP_032166 YP_674192 NP_102184 ZP_01227529 YP_781525 YP_577018 NP_771434 YP_001419167 YP_001525977 YP_001414407
Avi0013 Arad0014 NP_530727 YP_765616 YP_467573 NP_384118 NP_540740 YP_220899 YP_001368699 YP_031763 YP_676137 NP_105894 ZP_01228395 YP_778946 YP_575366 NP_767463 YP_001416775 YP_001523925 YP_001411287
Avi1845 Arad1978 NP_532621 YP_767383 YP_469202 NP_385467 NP_539679 YP_221932 YP_001370506 YP_032441 YP_674233 NP_102125 ZP_01225672 YP_782491 YP_576832 NP_772035 YP_001416586 YP_001525465 YP_001414006
Avi1578 Arad1727 NP_531840 YP_767202 YP_469020 NP_385292 NP_540155
YP_001371116 YP_032365 YP_674521 NP_108166 ZP_01227434 YP_782195 YP_577373 NP_770763 YP_001418015 YP_001523855 YP_001414589
Avi0441 Arad0659 NP_531065 YP_765999 YP_467922 NP_384514 NP_540890 YP_222787 YP_001369306 YP_031920 YP_676454 NP_106186 ZP_01228446 YP_779143 YP_575386 NP_767432 YP_001416715 YP_001522927 YP_001414875
Avi0036 Arad0056 NP_530755 YP_765647 YP_467603 NP_384158 NP_540959 YP_222721 YP_001369386
YP_676032 NP_105752 ZP_01228883 YP_779306 YP_575486 NP_767293 YP_001417190 YP_001527415 YP_001412511
Avi2470 Arad2631 NP_532047 YP_768229 YP_469838 NP_385912 NP_539868 YP_221749 YP_001370665
YP_673978 NP_102508 ZP_01228825 YP_783217 YP_578579 NP_773893 YP_001418996 YP_001524576
Avi1371 Arad1500 NP_531677 YP_767046 YP_468827 NP_385129 NP_540245 YP_221368 YP_001371206 YP_032079 YP_673465 NP_107960 ZP_01228735 YP_780867 YP_576729 NP_769772 YP_001418404
YP_001412225
Avi4391 Arad4944 NP_533498 YP_770302 YP_471594 NP_387445 NP_538921 YP_222701 YP_001369407 YP_032872 YP_676010 NP_105346 ZP_01228903 YP_779321 YP_575469 NP_767275 YP_001416726 YP_001527631 YP_001412537
Avi0164 Arad0177 NP_530799 YP_765732 YP_467671 NP_384342 NP_540885 YP_222792 YP_001369301 YP_031915 YP_676459 NP_106195 ZP_01228441 YP_779139 YP_575390 NP_767426 YP_001415211 YP_001522933 YP_001414880
Avi2881 Arad2984 NP_532760 YP_768876 YP_470334 NP_386273 NP_539503 YP_222110 YP_001370296 YP_032491 YP_674558 NP_103108 ZP_01226099 YP_781041 YP_576572 NP_773235 YP_001415244 YP_001527481 YP_001413695
Avi2558 Arad2618 NP_532554 YP_768221 YP_469830 NP_385905 NP_539704 YP_221906 YP_001370531 YP_032418 YP_673824 NP_101919 ZP_01228832 YP_780523 YP_576895 NP_772395 YP_001418959 YP_001525771 YP_001413844
Avi0045 Arad0045 NP_530748 YP_765639 YP_467595 NP_384149 NP_540952 YP_222727 YP_001369378 YP_031781 YP_676106 NP_105816 ZP_01228482 YP_779758 YP_575792 NP_774785 YP_001417743 YP_001526982 YP_001411392
Avi1460 Arad1607 NP_531748 YP_767127 YP_468932 NP_385208 NP_540201 YP_221418 YP_001371166

NP_102922 ZP_01228773 YP_783298 YP_579151 NP_769191 YP_001416379 YP_001523312 YP_001412017
Avi0402 Arad0618 NP_531037 YP_766031 YP_467955 NP_384486 NP_540704 YP_220929 YP_001368731
YP_676199 NP_104354 ZP_01228473 YP_779370 YP_575533 NP_767364 YP_001416936 YP_001523259 YP_001411471
Avi2085 Arad2684 NP_532297 YP_768279 YP_469884 NP_385960 NP_539889 YP_221728 YP_001370639 YP_032317 YP_674022 NP_102306 ZP_01225841 YP_780913 YP_576764 NP_770397 YP_001418110 YP_001525250 YP_001412373
Avi0578 Arad0785 NP_531182 YP_766174 YP_468078 NP_384630 NP_540544 YP_221082 YP_001368938 YP_031764 YP_672585 NP_106260 ZP_01226609 YP_779674 YP_575562 NP_767772 YP_001417283 YP_001523294
Avi0170 Arad0172 NP_530795 YP_765728 YP_467667 NP_384346 NP_540881 YP_222796 YP_001369297 YP_031911 YP_676463 NP_106199 ZP_01228437 YP_779135 YP_575394 NP_767422 YP_001415207 YP_001522937 YP_001414884
Avi4189 Arad4396 NP_533352 YP_770103 YP_471419 NP_387337 NP_540769 YP_220869 YP_001368667 YP_031826 YP_675895 NP_105229 ZP_01229020 YP_779251 YP_575761 NP_767108 YP_001418735 YP_001527375 YP_001412682
Avi1516 Arad1655 NP_531785 YP_767156 YP_468967 NP_385241 NP_540400 YP_221230 YP_001369126 YP_032127 YP_674476 NP_108078 ZP_01227396 YP_782228 YP_577665 NP_770716 YP_001418008 YP_001527220 YP_001414624
Avi2438 Arad2536 NP_532502 YP_768163 YP_469757 NP_385839 NP_539957 YP_221667 YP_001370798 YP_032251 YP_674338 NP_101911 ZP_01225602 YP_781882 YP_577578 NP_770981 YP_001419345 YP_001526529
Avi0429 Arad0648
YP_766008 YP_467931 NP_384506 NP_540724 YP_220912 YP_001368714 YP_032637 YP_676568 NP_106003 ZP_01228454 YP_779153 YP_575377 NP_767441 YP_001415212 YP_001527596 YP_001414865
Avi1731 Arad1867 NP_531975 YP_767320 YP_469146 NP_385387 NP_540060 YP_221559 YP_001370951 YP_032234 YP_673599 NP_102957 ZP_01225740 YP_781456 YP_577457 NP_771542 YP_001419495 YP_001524599 YP_001414474
Avi4210 Arad4429 NP_533368 YP_770117 YP_471434 NP_387352 NP_539074 YP_222556 YP_001369496 YP_032800 YP_675981 NP_105190 ZP_01229042 YP_779270 YP_578771 NP_767127 YP_001417409 YP_001526871 YP_001412699
Avi1472 Arad1624 NP_531761 YP_767138 YP_468945 NP_385226 NP_540409 YP_221220 YP_001369115 YP_032119 YP_673537 NP_108055 ZP_01227386 YP_780931 YP_576774 NP_770435 YP_001419063 YP_001524423 YP_001412391
Avi4295 Arad4928 NP_533490 YP_770286 YP_471579 NP_387430 NP_539153 YP_222472 YP_001369638 YP_032813 YP_675954 NP_105052 ZP_01228918 YP_778969 YP_575558 NP_767219 YP_001414954 YP_001527614 YP_001412603
Avi0299 Arad0271 NP_530819 YP_765765 YP_467703 NP_384281 NP_540742 YP_220897 YP_001368697 YP_031736 YP_676477 NP_104435 ZP_01228658 YP_783720 YP_575803 NP_774771 YP_001417277 YP_001527380 YP_001411385
Avi2484 Arad2026 NP_532594 YP_767411 YP_469230 NP_385491 NP_539701 YP_221910 YP_001370528 YP_032419 YP_674210 NP_102147 ZP_01225651 YP_782466 YP_576854 NP_772007 YP_001419645 YP_001525443 YP_001414030
Avi4114 Arad4319 NP_533293 YP_769996 YP_471352 NP_387152 NP_539065 YP_222563 YP_001369492 YP_032804 YP_675939 NP_105195 ZP_01228944 YP_779226 YP_575886 NP_767086 YP_001415079 YP_001526919 YP_001412734
Avi1073 Arad1261 NP_531485 YP_766671 YP_468515 NP_385025 NP_540369 YP_221256 YP_001369157
YP_673323 NP_107813 ZP_01228011 YP_783660 YP_575624 NP_767823 YP_001418412 YP_001525157 YP_001411959
Avi1471 Arad1622 NP_531760 YP_767137 YP_468941 NP_385227 NP_540408 YP_221221 YP_001369116 YP_032120 YP_673540 NP_108058 ZP_01227387 YP_780932 YP_576775 NP_770436 YP_001419539 YP_001524425 YP_001412392
Avi4384 Arad4937 NP_533415 YP_770296 YP_471588 NP_387439 NP_538929 YP_222694 YP_001369414 YP_032834 YP_675853 NP_105338 ZP_01228910 YP_779327 YP_575461 NP_767269 YP_001416353 YP_001523485
Avi1823 Arad1960 NP_532637 YP_767369 YP_469188 NP_385453 NP_539665 YP_221948 YP_001370491 YP_032350 YP_674378 NP_102109 ZP_01225683 YP_782508 YP_576812 NP_772051 YP_001418249 YP_001523802 YP_001413993
Avi2670 Arad2124 NP_532391 YP_767643 YP_469342 NP_385633 NP_540002 YP_221619 YP_001370889
YP_674367 NP_102753
YP_781612 YP_577036 NP_771392 YP_001419287 YP_001524650 YP_001414290
Avi1827 Arad1963 NP_532635 YP_767371 YP_469190 NP_385455 NP_539667 YP_221946 YP_001370493 YP_032348 YP_674376 NP_102111 ZP_01225681 YP_782506 YP_576814 NP_772049 YP_001418251 YP_001523804 YP_001413995
Avi0022 Arad0030 NP_530735 YP_765627 YP_467583 NP_384136 NP_540937 YP_222742 YP_001369364 YP_031759 YP_673228 NP_105800 ZP_01228496 YP_779395 YP_575422 NP_767387 YP_001416598 YP_001523940 YP_001411421
Avi2381 Arad2377 NP_532202 YP_767988 YP_469618 NP_385663 NP_539795 YP_221812 YP_001370745 YP_032410 YP_673957 NP_102491 ZP_01227558 YP_781807 YP_577338 NP_771342 YP_001419193 YP_001525803 YP_001414309
Avi4107 Arad4307 NP_533288 YP_769978 YP_471344 NP_387141 NP_539168 YP_222458 YP_001369653 YP_032753 YP_675754 NP_105024 ZP_01226747 YP_779220 YP_575881 NP_767081 YP_001416980 YP_001527042 YP_001412741
Avi3243 Arad3233 NP_532936 YP_769087 YP_470557 NP_386480 NP_539369 YP_222241 YP_001370146 YP_032541 YP_674744 NP_104051 ZP_01226225 YP_780330 YP_578455 NP_769097 YP_001416272 YP_001523808
Avi1819 Arad1957 NP_532640 YP_767365 YP_469185 NP_385450 NP_539662 YP_221951 YP_001370488 YP_032353 YP_674381 NP_102106 ZP_01225686 YP_782517 YP_576809 NP_772055 YP_001418246 YP_001523799 YP_001413990
Avi1520 Arad1658 NP_531788 YP_767159 YP_468970 NP_385244 NP_540397 YP_221233 YP_001369129 YP_032130 YP_674474 NP_108080 ZP_01227399 YP_782222 YP_577607 NP_770719 YP_001418005 YP_001527224 YP_001414622
Avi2110 Arad2245 NP_532118 YP_767834 YP_469445 NP_385550 NP_539770 YP_221836 YP_001370603 YP_032168 YP_674191 NP_102187
YP_781529 YP_577023 NP_771426 YP_001418768 YP_001524656 YP_001414406
Avi1470 Arad1620 NP_531759 YP_767136 YP_468940 NP_385228 NP_540407 YP_221222 YP_001369117 YP_032121 YP_673541 NP_108059 ZP_01227388 YP_780933 YP_576776 NP_770437 YP_001419538 YP_001524426 YP_001412393
Avi3166 Arad3170 NP_532880 YP_769033 YP_470503 NP_386444 NP_539409 YP_222202 YP_001370188 YP_032024 YP_674702 NP_103955 ZP_01226184 YP_780357 YP_578332 NP_774102 YP_001417458 YP_001526891 YP_001413539
Avi2134 Arad2264 NP_532135 YP_767850 YP_469460 NP_385564 NP_539782 YP_221825 YP_001370616
YP_674179 NP_102200 ZP_01227544 YP_781674 YP_577110 NP_771127 YP_001419278 YP_001526003 YP_001414394
Avi0042 Arad0047 NP_530750 YP_765641 YP_467597 NP_384151 NP_540954
YP_001369380
YP_676038 NP_105818 ZP_01228479 YP_779755 YP_575795 NP_774781 YP_001417740 YP_001526979 YP_001411389
Avi4277 Arad4889 NP_533441 YP_770252 YP_471546 NP_387270 NP_539129 YP_222495 YP_001369608
YP_675989 NP_104981 ZP_01226740 YP_779208 YP_575873 NP_767072 YP_001416962 YP_001527051 YP_001412752
Avi3227 Arad3217 NP_532924 YP_769077 YP_470544 NP_386469 NP_539379 YP_222231 YP_001370156
YP_674734 NP_104002 ZP_01226213 YP_779878 YP_578444 NP_769107 YP_001417843 YP_001526423 YP_001413507
Avi0292 Arad0372 NP_530921 YP_765827 YP_467764 NP_384255 NP_540865 YP_222810 YP_001369281 YP_031901 YP_676485 NP_106236 ZP_01227680 YP_782667 YP_575735 NP_768071 YP_001415196 YP_001523196 YP_001411522
Avi4193 Arad4399 NP_533355 YP_770105 YP_471422 NP_387340 NP_540766 YP_220872 YP_001368670 YP_031823 YP_675898 NP_105227 ZP_01229022 YP_779254 YP_575764 NP_767111 YP_001419008 YP_001527371 YP_001412685
Avi3104 Arad3117 NP_532840 YP_768982 YP_470444 NP_386420 NP_539449 YP_222163 YP_001370233 YP_032518 YP_674026 NP_103805 ZP_01225939 YP_779989 YP_578094 NP_773989 YP_001416144 YP_001526559 YP_001413588
Avi1452 Arad1597 NP_531736 YP_767119 YP_468924 NP_385194 NP_540202 YP_221417 YP_001371167 YP_032110 YP_673514 NP_108015 ZP_01228769 YP_781935 YP_577500 NP_771698 YP_001418767 YP_001524922 YP_001414140
Avi0418 Arad0636 NP_531050 YP_766015 YP_467939 NP_384499 NP_540717 YP_220917 YP_001368720
YP_676214 NP_104372 ZP_01228461 YP_779302 YP_576046
YP_001415248 YP_001522992 YP_001414852
Avi0589 Arad0795 NP_531191 YP_766184 YP_468088 NP_384652 NP_540531 YP_221095 YP_001368961
YP_672665 NP_106294
YP_779661 YP_575904 NP_767783 YP_001416371 YP_001523301 YP_001411731
Avi2417 Arad2568 NP_532521 YP_768185 YP_469780 NP_385865 NP_540034 YP_221588 YP_001370920 YP_032374 YP_673846 NP_101953 ZP_01228853 YP_780569 YP_577811 NP_772330 YP_001418730 YP_001525153 YP_001413862
Avi2270 Arad2154 NP_532293 YP_767666 YP_469367 NP_385834 NP_539635 YP_221982 YP_001370454 YP_032271 YP_674015 NP_102645 ZP_01227072 YP_779044 YP_575781 NP_774813 YP_001417939 YP_001527120 YP_001413864
Avi3139 Arad3143 NP_532858 YP_769008 YP_470469 NP_385673 NP_539429 YP_222181 YP_001370209 YP_032529 YP_674669 NP_103871 ZP_01225951 YP_782870 YP_578108 NP_774020 YP_001417650 YP_001524064 YP_001413576
Avi1717 Arad1848 NP_531964 YP_767308 YP_469134 NP_385375 NP_540071 YP_221548 YP_001370962 YP_032223 YP_673588 NP_102969 ZP_01225751 YP_781443 YP_577468 NP_771554 YP_001419506 YP_001524587 YP_001414485
Avi2518
NP_532070 YP_767821 YP_469432 NP_385607 NP_539746 YP_221862 YP_001370580 YP_032333 YP_673948 NP_102406 ZP_01227508 YP_781478 YP_576977 NP_771494 YP_001419310 YP_001524616 YP_001414452
Avi3262 Arad3250 NP_532946 YP_769097 YP_470565 NP_386491 NP_539721 YP_221888 YP_001370552
YP_673011 NP_108416 ZP_01228350 YP_781524 YP_577017 NP_771436 YP_001419166 YP_001525978 YP_001414414
Avi2966 Arad3069 NP_532829 YP_768941 YP_470396 NP_387087 NP_540676 YP_220956 YP_001368757
YP_672897
ZP_01226981 YP_782682 YP_575719 NP_768058 YP_001417729 YP_001527257 YP_001413669
Avi2563 Arad2236 NP_532082 YP_767828 YP_469439 NP_385615 NP_539753 YP_221854 YP_001370587 YP_032322 YP_674206 NP_102398 ZP_01227515 YP_781485 YP_576984 NP_771479 YP_001419303 YP_001524626 YP_001414444
Avi1613 Arad1754
YP_767225 YP_469040 NP_385316 NP_540106 YP_221512 YP_001371070 YP_032203 YP_673697 NP_108508 ZP_01227320 YP_781727 YP_577090 NP_771671 YP_001419156 YP_001524179 YP_001414174
Avi2070 Arad2706 NP_532382 YP_768313 YP_469913 NP_385972 NP_539937 YP_221681 YP_001370778
YP_674981 NP_102325 ZP_01226381 YP_782637 YP_578329 NP_768949 YP_001419302 YP_001524627
Avi0363 Arad0551 NP_531017 YP_765945 YP_467872 NP_384445 NP_540911
YP_001369333 YP_031765 YP_676117 NP_105484 ZP_01228362 YP_779299 YP_575491 NP_767301 YP_001415250 YP_001527258 YP_001414849
Avi2562 Arad2238 NP_532083 YP_767829 YP_469440 NP_385616 NP_539756 YP_221851 YP_001370589 YP_032320 YP_674204 NP_102396 ZP_01227517 YP_781488
NP_771470 YP_001419248 YP_001525116 YP_001414442
Avi2906 Arad3010 NP_532787 YP_768899 YP_470355 NP_386294 NP_539482 YP_222130 YP_001370277 YP_032579 YP_674576 NP_103126 ZP_01226121 YP_781022 YP_576555 NP_773251 YP_001416798 YP_001527465 YP_001413676
Avi4347 Arad4675 NP_533418 YP_770182 YP_471493 NP_387366 NP_539193 YP_222433 YP_001369680 YP_032742 YP_675912 NP_104867 ZP_01228199 YP_779068 YP_575854 NP_766799 YP_001417538 YP_001523146 YP_001412974
Avi4148 Arad4359 NP_533321 YP_770065 YP_471380 NP_387188 NP_539097 YP_222534 YP_001369528 YP_032822 YP_675736 NP_105142 ZP_01228979 YP_779003 YP_575915 NP_767204 YP_001416067 YP_001523174 YP_001412629
Avi2040 Arad2676 NP_532342 YP_768273 YP_469878 NP_385952 NP_539886 YP_221731 YP_001370642 YP_032315 YP_674024 NP_102540 ZP_01225834 YP_780917 YP_576767 NP_770420 YP_001416282 YP_001523829 YP_001412381
Avi4299 Arad4891 NP_533440 YP_770253 YP_471547 NP_387271 NP_539131 YP_222493 YP_001369610 YP_031862 YP_675988 NP_104980
YP_779209 YP_575874 NP_767073 YP_001416972 YP_001527050 YP_001412750
Avi3171 Arad3177 NP_532886 YP_769043 YP_470512 NP_386449 NP_539405 YP_222206 YP_001370184 YP_032020 YP_674707 NP_103962 ZP_01226189 YP_780365 YP_578292 NP_774084 YP_001417447 YP_001526898 YP_001413533
Avi2683 Arad2111 NP_532403 YP_767633 YP_469331 NP_385622 NP_539944 YP_221680 YP_001370786 YP_032457 YP_674132 NP_102766 ZP_01227283 YP_781667 YP_577102 NP_771115 YP_001419115 YP_001525731 YP_001414270
Avi2033 Arad2776 NP_532283 YP_768400 YP_469980 NP_386046 NP_540029 YP_221593 YP_001370915 YP_032192 YP_673880 NP_102825 ZP_01226012 YP_780945 YP_576786 NP_770449 YP_001416167 YP_001525321
Avi2980 Arad3099 NP_532835 YP_768962 YP_470429 NP_386413 NP_539453 YP_222159 YP_001370238 YP_032517 YP_674631 NP_103761 ZP_01225935 YP_779262 YP_578766 NP_767119 YP_001418331 YP_001524377 YP_001413592
Avi4226 Arad4443 NP_533429 YP_770123 YP_471439 NP_387310 NP_538983 YP_222647 YP_001369516
YP_675959 NP_105155 ZP_01228969 YP_779332 YP_575456 NP_767261 YP_001416672 YP_001523005 YP_001412563
Avi4145 Arad4356 NP_533317 YP_770062 YP_471377 NP_387185 NP_539094 YP_222537 YP_001369525
YP_675739 NP_105145 ZP_01228976 YP_780237 YP_575912 NP_769038 YP_001416064 YP_001523177 YP_001412626
Avi0945 Arad1134 NP_531336 YP_766551 YP_468415 NP_384954 NP_540451 YP_221179 YP_001369077 YP_032009 YP_673274 NP_107744 ZP_01228059 YP_783318 YP_578409 NP_769173 YP_001416280 YP_001523821 YP_001412004
Avi1542 Arad1682 NP_531804 YP_767172 YP_468983 NP_385259 NP_540180 YP_221441 YP_001371144 YP_032142 YP_674317 NP_108095 ZP_01227411 YP_782206 YP_577593 NP_770746 YP_001417734 YP_001527240 YP_001414600
Avi1543 Arad1683 NP_531805 YP_767173 YP_468984 NP_385260 NP_540179 YP_221442 YP_001371143 YP_032143 YP_674316 NP_108096 ZP_01227412 YP_782205 YP_577592 NP_770747 YP_001417735 YP_001527241
Avi2667 Arad2127 NP_532389 YP_767645 YP_469344 NP_385636
YP_221621 YP_001370887 YP_032153 YP_674364
ZP_01227294 YP_781614 YP_577063 NP_771390 YP_001419284 YP_001524653 YP_001414292
Avi2675 Arad2119 NP_532395 YP_767639 YP_469338 NP_385629 NP_540006 YP_221615 YP_001370894 YP_032398 YP_674372 NP_102757 ZP_01227290 YP_781608 YP_577032 NP_771397 YP_001419123 YP_001525722 YP_001414286
Avi1602 Arad1745 NP_531857 YP_767219 YP_469033 NP_385309 NP_540115 YP_221502 YP_001371079
YP_673689 NP_108477 ZP_01227443 YP_781927 YP_577493 NP_771678 YP_001419171 YP_001524457 YP_001414149
Avi2794 Arad2885 NP_532700 YP_768802 YP_470265 NP_386192 NP_539538 YP_222073 YP_001370355 YP_032471 YP_674054 NP_103012 ZP_01227127 YP_781942 YP_577506 NP_771704 YP_001418759 YP_001524917 YP_001414135
Avi2532 Arad2215 NP_532061 YP_767811 YP_469423 NP_385598 NP_539736 YP_221872 YP_001370571
YP_673939 NP_102420 ZP_01227499 YP_782304 YP_577699 NP_771773 YP_001418674 YP_001525235
Avi2202 Arad2480 NP_532436 YP_768119 YP_469713 NP_385522 NP_539656 YP_221958 YP_001370482 YP_032358 YP_674282 NP_102039 ZP_01225711 YP_781250 YP_576926 NP_772192 YP_001417261 YP_001526585 YP_001413918
Avi2895 Arad3001 NP_532773 YP_768890 YP_470346 NP_386286 NP_539492 YP_222121 YP_001370285 YP_032502 YP_674569 NP_103119 ZP_01226110 YP_781027 YP_576560 NP_773246 YP_001416750 YP_001527458 YP_001413683
Avi2885 Arad2989 NP_532763 YP_768879 YP_470337 NP_386276 NP_539500 YP_222113 YP_001370293 YP_032494 YP_674561 NP_103111 ZP_01226102 YP_781038 YP_576569 NP_773238 YP_001415241 YP_001527478 YP_001413691
Avi2519 Arad2225 NP_532069 YP_767820 YP_469431 NP_385606 NP_539745 YP_221863 YP_001370579 YP_032334 YP_673947 NP_102407 ZP_01227507 YP_781476 YP_576975 NP_771496 YP_001419312 YP_001524614 YP_001414454

Arad1767 NP_531872 YP_767240 YP_469059 NP_385326 NP_540100 YP_221518 YP_001371064
YP_673704 NP_108519 ZP_01227327 YP_781740 YP_576864 NP_771663 YP_001419260 YP_001525213 YP_001414184
Avi1539 Arad1679 NP_531802 YP_767170 YP_468981 NP_385257 NP_540182 YP_221439 YP_001371146 YP_032140 YP_674319 NP_108093 ZP_01227409 YP_782208 YP_577595 NP_770744 YP_001417732

Avi2529 Arad2217 NP_532063 YP_767813 YP_469425 NP_385600 NP_539738 YP_221870 YP_001370573 YP_032339 YP_673941 NP_102418 ZP_01227159 YP_782302 YP_577696 NP_771771
YP_001525233
Avi3642 Arad3724
YP_769581 YP_470976 NP_386866 NP_539230 YP_222389 YP_001369738 YP_032734 YP_675978 NP_104785 ZP_01226646 YP_783630 YP_578718 NP_768166 YP_001417960 YP_001523423 YP_001413381
Avi0433 Arad0652 NP_531059 YP_766005 YP_467928 NP_384509 NP_540895 YP_222782 YP_001369311 YP_031924 YP_676449 NP_106181 ZP_01228451 YP_779149 YP_575381 NP_767438 YP_001416723 YP_001527621 YP_001414869
Avi0408 Arad0623 NP_531041 YP_766026 YP_467950 NP_384490 NP_540709 YP_220924 YP_001368727 YP_031743 YP_676203 NP_104358 ZP_01228469 YP_779366 YP_575539 NP_767360 YP_001414983 YP_001526844
Avi1322 Arad1485 NP_531624 YP_766998 YP_468792 NP_385115 NP_540269 YP_221342 YP_001371219 YP_032068 YP_673447 NP_107930 ZP_01227026 YP_780807 YP_576684 NP_769741 YP_001416315 YP_001524014
Avi1361 Arad1492 NP_531670 YP_767039 YP_468820 NP_385122 NP_540252 YP_221361 YP_001371213
YP_673458 NP_107953 ZP_01227054 YP_780854 YP_576717
YP_001418065 YP_001524047 YP_001412069
Avi1627 Arad1768 NP_531873 YP_767241 YP_469060 NP_385327 NP_540099 YP_221519 YP_001371063 YP_032208 YP_673705 NP_108520 ZP_01227328 YP_781741 YP_576865 NP_771662 YP_001419261 YP_001525212 YP_001414185
Avi2565 Arad2435 NP_532370 YP_768076 YP_469682 NP_385765 NP_539762 YP_221845 YP_001370595 YP_032161 YP_674197 NP_102382 ZP_01227523 YP_781510 YP_577010 NP_771448 YP_001419257 YP_001525125 YP_001414431
Avi3106 Arad3123 NP_532841 YP_768988 YP_470448 NP_386424 NP_539447 YP_222164 YP_001370231 YP_032519 YP_674025 NP_103806 ZP_01225940 YP_779990 YP_578095 NP_773990 YP_001416145 YP_001526558 YP_001413587
Avi0534 Arad0744 NP_531109 YP_766113 YP_468025 NP_384589 NP_540553 YP_221072 YP_001368929 YP_031847 YP_672640 NP_106081 ZP_01227904 YP_782617 YP_578463 NP_773398 YP_001416156 YP_001526547






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Table S6. Key gene clusters shared by chromosome II in several strains of Brucella (represented by B. suis 1330), chromosome II in Ochrobactrum anthropi, chromosome II in biovar 1 (C58) and 3 (S4) strains of Agrobacterium, 2651 kbp replicon in biovar 2 (K84) of Agrobacterium, plasmid p42e of Rhizobium etli (R.etli), plasmid pRL11 of Rhizobium leguminosarum (R.legum), and plasmid pSymB of Sinorhizobium (S.mel), most likely due to a shared repABC-type plasmid precursor (labeled IRT in the research article) that either entered an ancestral genome carrying these gene clusters and/or resulted from an ancestral intragenome gene transfer from chromosome I to the IRT plasmid early in the Rhizobiales lineage.

 

Product

Gene number

 

B. suis

O.anthropi

C58

S4

K84

R. etli

R. legum

S. mel

RepC1 replication protein Ca

BRA0001

Oant_4454

Atu3922

Avi5002

Arad7003

RHE_PE00459

pRL110003

SM_b20044

RepB1 replication protein Ba

BRA1203

Oant_4455

Atu3923

Avi5001

Arad7001

RHE_PE00458

pRL110002

SM_b20045

RepA1 replication protein Aa

BRA1202

Oant_4456

Atu3924

Avi5000

Arad7000

RHE_PE00457

pRL110001

SM_b20046

 

PcaB 3-carboxy-cis,cis-muconate Cycloisomeraseb

BRA0647

Oant_3729

Atu4538

Avi6130

Arad9505

RHE_PE00055

pRL110085

SM_b20575

PcaG protocatechuate 3,4-dioxygenase alpha chainb

BRA0646

Oant_3728

Atu4539

Avi6129

Arad9504

RHE_PE00056

pRL110086

SM_b20576

PcaH protocatechuate 3,4-dioxygenase beta chainb

BRA0645

Oant_3727

Atu4540

Avi6128

Arad9503

RHE_PE00057

pRL110087

SM_b20577

PcaC gamma carboxymuconolactone decarboxylaseb

BRA0644

Oant_3726

Atu4541

Avi6127

Arad9502

RHE_PE00058

pRL110088

SM_b20578

PcaD beta-ketoadipate enol-lactone hydrolaseb

BRA0643

Oant_3725

Atu4542

Avi6126

Arad9500

RHE_PE00059

pRL110089

SM_b20579

PcaQ transcriptional activatorb

BRA0642

Oant_3724

Atu4543

Avi6124

Arad9499

RHE_PE00060

pRL110090

SM_b20580

4-hydroxybenzoate hydroxylaseb

BRA0641

Oant_3723

Atu4544

Avi6123

Arad9498

RHE_CH03444

RL3905

SM_b20583

Transcriptional regulator, AraC familyb

BRA0640

Oant_3722

Atu4545

Avi6122

Arad9497

RHE_CH03443

RL3904

 

IclR family transcriptional regulatorb

BRA0639

Oant_3721

Atu4546

Avi6121

Arad9496

RHE_PE00200

pRL110286

SM_b20586

CoA-transferase subunit Ab

BRA0648

Oant_3720

Atu4547

Avi6120

Arad9494

RHE_PE00201

pRL110287

SM_b20587

3-oxoadipate CoA-transferase subunitBb

BRA0637

Oant_3719

Atu4548

Avi6118

Arad9491

RHE_PE00202

pRL110288

SM_b20588

PcaF beta-ketoadipyl CoA thiolaseb

BRA0636

Oant_3718

Atu4549

Avi6117

Arad9490

RHE_PE00203

pRL110289

SM_b20589

 

HutU urocanasea

BRA0932

Oant_1433c

Atu3931

Avi5956

Arad4562 d

RHE_PE00070

pRL110203

SM_b21163

HutG formiminoglutamasea

BRA0931

Oant_1434c

Atu3932

Avi5957

 

RHE_PE00071

pRL110204

SM_b21164

HutH1 histidine ammonia-lyasea

BRA0930

Oant_1435c

Atu3933

Avi5958

Arad4563 d

RHE_PE00072

pRL110205

SM_b21165

HutI imidazolonepropionasea

BRA0929

Oant_1436c

Atu3934

Avi5959

Arad4564 d

RHE_PE00073

pRL110206

SM_b21166

N-formimino-L-glutamate deiminasea

BRA0928

Oant_1437c

Atu3935

Avi5960

Arad4565 d

RHE_PE00074

pRL110207

SMc00673

Transcriptional regulator, GntR familya

BRA0927

Oant_1438c

Atu3936

Avi5963

Arad4566 d

RHE_PE00075

pRL110208

SM_b20048

 

MinE cell division inhibitora

BRA0323

Oant_2972

Atu3247

Avi3506 e

Arad8858

RHE_PE00407

pRL110544

SM_b21522

MinD cell division inhibitora

BRA0322

Oant_2971

Atu3248

Avi3507 e

Arad8857

RHE_PE00408

pRL110545

SM_b21523

MinC cell division inhibitora

BRA0321

Oant_2970

Atu3249

Avi3508 e

Arad8856

RHE_PE00409

pRL110546

SM_b21524

 

a These genes are absent from the unichromosome genome of Azorhizobium caulidans, also of the Rhizobiales, in support of IRT plasmid origin.

b These genes are present in the unichromosome genome of Azorhizobium caulidans, also of the Rhizobiales (supports intragenome transfer to IRT plasmid).

c These genes are on chromosome I in Ochrobacter anthropi, most likely due to a intragenome transfer in the opposite direction from IRT to chromosome I. The presence of a larger syntenic cluster that houses the hut gene cluster on ChrII of all Brucella species and ChrI of O. anthropi supports a retrotransfer after the split of these two lineages from their most recent common ancestor.

d These genes are on chromosome I in Agrobacterium radiobacter, most likely due to a intragenome transfer in the opposite direction from IRT to chromosome I. The presence of a larger syntenic cluster that houses the hut gene cluster on ChrII of Rhizobium etli and R. leguminosarum but on ChrI of A. radiobacter supports a retrotransfer after the divergence of the biovar II lineage from the biovar I/III lineage.

e These genes are on chromosome I in Agrobacterium vitis, most likely due to a intragenome transfer in the opposite direction from IRT to chromosome I. There is no larger syntenic support for this explanation, but is it is the simplest explanation given that the minCDE operon is found rarely in the alpha-Proteobacteria outside of the Rhizobiales and it is only found on second chromosomes or megareplicons in all other members of the Rhizobiales except A. vitis. This retrotransfer occurred after the divergence of the biovar III and biovar I lineages.

 







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Table S7. Key gene clusters shared by chromosome I of Sinorhizobium meliloti (extant representative of ancestral chromosome I) and by chromosome II of all sequenced Brucella strains (Brucella abortus biovar 1 strain 9-941 used as an example) and chromosome II of Ochrobactrum anthropi. These gene clusters are presumed to have moved from the ancestral chromosome I to the IRT plasmid-derived chromosome II prior to the divergence of the Brucella and Ochrobactrum clades.

 

Product

Gene ID

 

S. meliloti

B. abortus

O. anthropi

response regulator

SMc04044

BruAb2_0043

Oant_4284

hypothetical formiminoglutamase

SMc04043

BruAb2_0044

Oant_4283

inositol monophosphatase family protein

SMc04042

BruAb2_0045

Oant_4282

hypothetical lysophospholipase L2

SMc04041

BruAb2_0046

Oant_4281

hypothetical threonine aldolase, low-specificity

SMc04029

BruAb2_0052

Oant_4278

GltB glutamate synthase, large subunit

SMc04028

BruAb2_0054

Oant_4277

conserved hypothetical protein

SMc04025

BruAb2_0057

Oant_4274

hypothetical transglycosylase

SMc04024

BruAb2_0070

Oant_4273

GalU UTP--glucose-1-phosphate uridylyltransferase

SMc04023

BruAb2_0071

Oant_4272

KpsF/GutQ sugar isomerase

SMc02268

BruAb2_0073

Oant_4269

conserved hypothetical protein

SMc04021

BruAb2_0074

Oant_4268

SPFH domain/Band 7 family protein

SMc04020

BruAb2_0075

Oant_4267

Omp10 lipoprotein

SMc04017

BruAb2_0077

Oant_4265

homospermidine synthase

SMc04016

BruAb2_0078

Oant_4263

para-aminobenzoate synthase, component I

SMc04014

BruAb2_0079

Oant_4262

para-aminobenzoate synthase, component I

SMc04013

BruAb2_0080

Oant_4261

PepF oligoendopeptidase F

SMc04012

BruAb2_0081

Oant_4260

conserved hypothetical protein

SMc04010

BruAb2_0083

Oant_4258

 

high-affinity nickel-transporter

SMc02986

BruAb2_0095

Oant_4249

hypothetical protein

SMc02985

BruAb2_0096

Oant_4248

LysR family transcriptional regulator

SMc02984

BruAb2_0097

Oant_4247

 

 

 

 

spermidine/putrescine ABC transporter, ATP-binding protein

SMc01608

BruAb2_0110

Oant_4232

spermidine/putrescine ABC transporter permease

SMc01607

BruAb2_0111

Oant_4231

spermidine/putrescine ABC transporter permease

SMc01606

BruAb2_0112

Oant_4230

BC transporter, periplasmic substrate-binding protein

SMc01605

BruAb2_0113

Oant_4228

 

 

 

 

conserved hypothetical protein

SMc03017

BruAb2_0118

Oant_4223

flagellar biosynthetic protein FlhB

SMc03018

BruAb2_0119

Oant_4222

chemotaxis motA protein

SMc03022

BruAb2_0124

Oant_4217

conserved hypothetical protein

SMc03023

BruAb2_0125

Oant_4216

FlgF flagellar basal-body rod protein FlgF

SMc03024

BruAb2_0126

Oant_4215

flagellum-specific ATP synthase FliI

SMc03025

BruAb2_0127

Oant_4214

conserved hypothetical protein

SMc03926

BruAb2_0128

Oant_4213

FlgB flagellar basal-body rod protein

SMc03027

BruAb2_0147

Oant_4212

FlgC flagellar basal-body rod rotein FlgC

SMc03928

BruAb2_0148

Oant_4211

FliE flagellar hook-basal body complex protein

SMc03029

BruAb2_0149

Oant_4210

flagellar basal-body rod protein FlgG

SMc03030

BruAb2_0150

Oant_4209

FlgA flagellar basal-body P-ring formation protein

SMc03031

BruAb2_0151

Oant_4208

conserved hypothetical protein

SMc03033

BruAb2_0153

Oant_4206

FlgH flagellar L-ring protein

SMc03034

BruAb2_0154

Oant_4205

FliP flagellar biosynthetic protein

SMc03036

BruAb2_0156

Oant_4203

 

ErfK/YbiS/YcfS/YnhG family protein

SMc00924

BruAb2_0179

Oant_3014

DNA-3-methyladenine glycosidase I

SMc00923

BruAb2_0180

Oant_3015

HisS histidyl-tRNA synthetase

SMc00919

BruAb2_0182

Oant_3017

conserved hypothetical protein

SMc00918

BruAb2_0183

Oant_3018

hypothetical ATP phosphoribosyltransferase

SMc00917

BruAb2_0184

Oant_3019

GroEL 60 kDa chaperonin

SMc01758

BruAb2_0190

Oant_3026

GroES chaperonin, 10 kDa

SMc00912

BruAb2_0191

Oant_3027

hydrolase, haloacid dehalogenase-like family

SMc00910

BruAb2_0194

Oant_3029

RibF riboflavin biosynthesis protein

SMc00909

BruAb2_0196

Oant_3030

IleS isoleucyl-tRNA synthetase

SMc00908

BruAb2_0197

Oant_3032

conserved hypothetical protein

SMc00907

BruAb2_0198

Oant_3033

conserved hypothetical protein

SMc00902

BruAb2_0202

a

conserved hypothetical protein

SMc01003

BruAb2_0205

a

hypothetical glutathione-regulated potassium-efflux system protein

SMc00898

BruAb2_0206

Oant_3041

PmbA protein

SMc00897

BruAb2_0207

Oant_3042

inositol monophosphatase family protein

SMc00896

BruAb2_0208

Oant_3043

conserved hypothetical protein

SMc00895

BruAb2_0209

Oant_3044

conserved hypothetical protein

SMc00933

BruAb2_0213

Oant_3048

MutL DNA mismatch repair protein

SMc00932

BruAb2_0214

Oant_3049

 

conserved hypothetical protein

SMc03800

BruAb2_0338

Oant_3283

Trx-2 thioredoxin

SMc03801

BruAb2_0339

Oant_3284

hypothetical ATP-dependent protease La

SMc03802

BruAb2_0340

Oant_3285

conserved hypothetical protein

SMc03803

BruAb2_0341

Oant_3286

 

MarR family transcriptional regulator

SMc00098

BruAb2_0346

Oant_3291

Ohr organic hydroperoxide resistance protein

SMc00040

BruAb2_0347

Oant_3292

 

 

 

 

hypothetical protein

SMc02149

BruAb2_0401

Oant_4047

2-nitropropane dioxygenase family protein

SMc02150

BruAb2_0402

Oant_4046

 

 

 

 

ATP-dependent RNA helicase, DEAD/DEAH box family

SMc02237

BruAb2_0406

Oant_4042

conserved hypothetical protein

SMc02236

BruAb2_0407

Oant_4041

conserved hypothetical protein

SMc02234

BruAb2_0408

Oant_4040

hypothetical membrane protein

SMc02232

BruAb2_0409

Oant_4039

acyl-CoA dehydrogenase family protein

SMc02229

BruAb2_0437

Oant_4033

hypothetical fatty oxidation complex, beta subunit

SMc02228

BruAb2_0438

Oant_4032

FadB, fatty oxidation complex, alpha subunit

SMc02227

BruAb2_0439

Oant_4031

peptidase, S24 family

SMc02223

BruAb2_0440

Oant_4030

conserved hypothetical protein

SMc02222

BruAb2_0441

Oant_4029

 

 

 

 

AzlC family protein

SMc00559

BruAb2_0458

Oant_3946

branched-chain amino acid transport

SMc00560

BruAb2_0457

Oant_3947

 

glutamate--putrescine ligase

SMc00762

BruAb2_0464

Oant_3936

FAD dependent oxidoreductase

SMc00761

BruAb2_0462

Oant_3937

Pgl 6-phosphogluconolactonase

SMc03069

BruAb2_0453

Oant_3957

Zwf glucose-6-phosphate 1-dehydrogenase

SMc03070

BruAb2_0454

Oant_3956

 

GcvT glycine cleavage system T protein

SMc02047

BruAb2_0504

Oant_3862

GcvH glycine cleavage system H protein

SMc02048

BruAb2_0505

Oant_3863

GcvP glycine cleavage system P protein

SMc02049

BruAb2_0506

Oant_3864

 

IolD, TPP-requiring enzyme

SMc01166

BruAb2_0515

Oant_3838

IolE protein

SMc00433

BruAb2_0516

Oant_3839

 

hypothetical ribosomal RNA large subunit methyltransferase J

SMc00811

BruAb2_0543

Oant_3812

phosphatase, Ppx/GppA family

SMc00810

BruAb2_0544

Oant_3811

 

conserved hypothetical protein

SMc01372

BruAb2_0612

Oant_3679

DivK polar differentiation response regulator

SMc01371

BruAb2_0613

Oant_3678

response regulator/GGDEF domain protein

SMc01370

BruAb2_0614

Oant_3677

RpmG ribosomal protein L33

SMc01369

BruAb2_0615

Oant_3676

major facilitator family transporter

SMc01368

BruAb2_0616

Oant_3675

conserved hypothetical protein

SMc01366

BruAb2_0618

Oant_3673

exoribonuclease, VacB/RNase II family

SMc01365

BruAb2_0619

Oant_3672

TopA DNA topoisomerase I

SMc01364

BruAb2_0620

Oant_3671

hypothetical membrane protein

SMc01362

BruAb2_0623

Oant_3668

PyrC-2 dihydroorotase, multifunctional complex type

SMc01361

BruAb2_0624

Oant_3667

PyrB aspartate carbamoyltransferase

SMc01360

BruAb2_0625

Oant_3666

acyl-CoA dehydrogenase family protein

SMc01359

BruAb2_0626

Oant_3665

conserved hypothetical protein TIGR00250

SMc01355

BruAb2_0627

Oant_3664

metallo-beta-lactamase family protein

SMc01354

BruAb2_0628

Oant_3663

GatC glutamyl-tRNA(Gln) amidotransferase, C subunit

SMc01353

BruAb2_0629

Oant_3662

GatA glutamyl-tRNA(Gln) amidotransferase, A subunit

SMc01352

BruAb2_0630

Oant_3660

 

GlmU UDP-N-acetylglucosamine pyrophosphorylase

SMc00232

BruAb2_0641

Oant_3644

GlmS glucosamine--fructose-6-phosphate aminotransferase

SMc00231

BruAb2_0642

Oant_3643

RecG ATP-dependent DNA helicase

SMc00228

BruAb2_0643

Oant_3642

conserved hypothetical protein

SMc00227

BruAb2_0644

Oant_3641

transcription-repair coupling factor

SMc04450

BruAb2_0645

Oant_3640

oxidoreductase

SMc00952

BruAb2_0647

Oant_3639

extracellular solute-binding protein

SMc00951

BruAb2_0648

Oant_3638

invasion associated locus B family protein

SMc00950

BruAb2_0649

Oant_3637

hemimethylated DNA binding protein

SMc00949

BruAb2_0650

Oant_3636

 

2-octaprenyl-6-methoxyphenyl hydroxylase

SMc00316

BruAb2_0651

Oant_3635

Pcs phosphatidylcholine synthase

SMc00247

BruAb2_0652

Oant_3634

ABC transporter, ATP-binding protein

SMc00245

BruAb2_0654

Oant_3632

ABC transporter, permease protein

SMc00243

BruAb2_0655

Oant_3631

ABC transporter, permease protein

SMc00244

BruAb2_0656

Oant_3630

 

Bfr bacterioferritin

SMc03786

BruAb2_0659

Oant_3626

conserved hypothetical protein

SMc03787

BruAb2_0660

Oant_3625

 

branched-chain alpha-keto acid dehydrogenase subunit E2

SMc03203

BruAb2_0698

Oant_3553

2-oxoisovalerate dehydrogenase beta subunit

SMc03202

BruAb2_0699

Oant_3552

2-oxoisovalerate dehydrogenase alpha subunit

SMc03201

BruAb2_0700

Oant_3551

 

 

 

 

putative oxidoreductase protein

SMc04138

BruAb2_0703

Oant_3549

ABC transporter permease

SMc04137

BruAb2_0704

Oant_3548

ABC transporter permease

SMc04136

BruAb2_0705

Oant_3547

putative periplasmic binding (signal peptide) ABC transporter protein

SMc04135

BruAb2_0707

Oant_3546

hypothetical protein

SMc02875

BruAb2_0708

Oant_3545

putative transcription regulator protein

SMc02876

BruAb2_0709

Oant_3544

 

putative quinol oxidase subunit II transmembrane protein

SMc02254

BruAb2_0711

Oant_3542

putative quinol oxidase subunit I transmembrane protein

SMc02255

BruAb2_0712

Oant_3541

 

monovalent cation/proton antiporter, MnhG/PhaG subunit

SMc03184

BruAb2_0717

Oant_3536

monovalent cation/proton antiporter, MnhF/PhaF subunit

SMc03183

BruAb2_0718

Oant_3535

monovalent cation/proton antiporter, MnhE/PhaE subunit

SMc03182

BruAb2_0719

Oant_3534

monovalent cation/proton antiporter, MnhD/PhaD subunit

SMc03181

BruAb2_0720

Oant_3533

monovalent cation/proton antiporter, MnhC/PhaC subunit

SMc03180

BruAb2_0721

Oant_3532

 

EmrB/QacA family drug resistance transporter

SMc00563

BruAb2_0751

Oant_4227

HlyD family secretion protein

SMc00564

BruAb2_0750

Oant_4226

 

 

 

 

GuaA GMP synthase

SMc00394

BruAb2_0821

Oant_3058

MTA/SAH nucleosidase family protein

SMc00395

BruAb2_0822

Oant_3057

conserved hypothetical protein

SMc00396

BruAb2_0823

Oant_3056

 

KatA catalase

SMc00819

BruAb2_0827

Oant_3054

transcriptional regulator OxyR

SMc00818

BruAb2_0828

Oant_3053

 

ZnuA, zinc ABC transporter, periplasmic zinc-bnding protein

SMc04245

BruAb2_1059

Oant_4176

ZnuC, zinc ABC transporter, ATP binding protein

SMc04244

BruAb2_1060

Oant_4177

ZnuB, zinc ABC transporter, permease protein

SMc04243

BruAb2_1061

Oant_4178

transcriptional regulator, Fur family

SMc04242

BruAb2_1062

Oant_4179

 

conserved hypothetical protein

SMc03057

BruAb2_1064

Oant_4181

conserved hypothetical protein

SMc03072

BruAb2_1065

Oant_4182

conserved hypothetical protein

SMc03071

BruAb2_1066

Oant_4183

hypothetical FliR, flagellar biosynthesis protein

SMc03055

BruAb2_1068

Oant_4185

FlhA flagellar biosynthesis protein

SMc03054

BruAb2_1069

Oant_4186

FliQ flagellar biosynthesis protein

SMc03953

BruAb2_1070

Oant_4187

hypothetical FlgD basal-body rod modification protein

SMc03952

BruAb2_1071

Oant_4188

hypothetical FlbT, flagellar protein

SMc03951

BruAb2_1072

Oant_4189

hypothetical FlaF

SMc03050

BruAb2_1073

Oant_4190

FlgE flagellar hook protein

SMc03047

BruAb2_1076

Oant_4193

transcriptional regulator

SMc03046

BruAb2_1077

Oant_4194

conserved hypothetical protein

SMc03045

BruAb2_1078

Oant_4195

 

a These genes appear to have been lost from the genome.

 







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Table S8. Key gene clusters shared by chromosome I of Sinorhizobium meliloti (extant representative of ancestral chromosome I) and by chromosome II of all sequenced Brucella strains (Brucella abortus biovar 1 strain 9-941 used as an example), but not shared by chromosome II of Ochrobactrum anthropi. These gene clusters are presumed to have moved from the ancestral chromosome I to the plasmid-derived chromosome II in the Brucella lineage after its divergence from the Ochrobactrum clade.

 

 

Product

Gene ID

 

S. meliloti

B. abortus

putative sulfite oxidase subunit YedZ

SMc01281

BruAb2_0243

putative sulfite oxidase subunit YedY

SMc01282

BruAb2_0244

 

WD repeat-containing protein

SMc02979

BruAb2_0246

cobalamin synthesis protein/P47K family protein

SMc02978

BruAb2_0247

creatinine amidohydrolase

SMc02977

BruAb2_0248

 

conserved hypothetical protein

SMc03941

BruAb2_0259

PntA, NAD(P) transhydrogenase, alpha subunit

SMc03950

BruAb2_0260

PntAB, NAD(P) transhydrogenase, alpha2 subunit

SMc03939

BruAb2_0261

PntB, NAD(P) transhydrogenase, beta subunit

SMc03938

BruAb2_0262

 

ABC transporter, permease protein

SMc03158

BruAb2_0271

ABC transporter, ATP-binding protein

SMc03159

BruAb2_0272

lipoprotein, YaeC family

SMc03157

BruAb2_0273

oxidoreductase, GMC family

SMc03116

BruAb2_0275

branched-chain amino acid ABC transporter, permease protein

SMc03117

BruAb2_0276

branched-chain amino acid ABC transporter, permease protein

SMc03118

BruAb2_0277

branched-chain amino acid ABC transporter, ATP-binding protein

SMc03119

BruAb2_0278

branched-chain amino acid ABC transporter, ATP-binding protein

SMc03120

BruAb2_0279

branched-chain amino acid ABC transporter, periplasmic binding protein

SMc03121

BruAb2_0280

transcriptional regulator, LysR family

SMc03122

BruAb2_0281

 

DgoK, 2-dehydro-3-deoxygalactonokinase

SMc00881

BruAb2_0294

2-dehydro-3-deoxyphosphogalactonate aldolase, hypothetical

SMc00882

BruAb2_0295

 

conserved hypothetical protein

SMc00667

BruAb2_0300

HutH, histidine ammonia-lyase

SMc00669

BruAb2_0303

Atz/Trz family protein

SMc00673

BruAb2_0305

HutC histidine utilization repressor

SMc00674

BruAb2_0306

 

omega-amino acid--pyruvate aminotransferase

SMc04388

BruAb2_0307

transcriptional regulator, hypothetical

SMc04387

BruAb2_0308

aldehyde dehydrogenase family protein

SMc04385

BruAb2_0325

conserved hypothetical protein

SMc04383

BruAb2_0326

LysR family transcriptional regulator

SMc04882

BruAb2_0327

 

ArsR family transcriptional regulator

SMc01226

BruAb2_0330

oxidoreductase, FMN-binding

SMc01227

BruAb2_0331

 

transcriptional regulator, AsnC family

SMc03092

BruAb2_0332

RocF, arginase

SMc03091

BruAb2_0333

 

D-amino acid oxidase family protein

SMc00761

BruAb2_0462

glutamine synthetase family protein

SMc00762

BruAb2_0464

transcriptional regulator, LysR family

SMc00820

BruAb2_0467

 

alcohol dehydrogenase, iron-containing

SMc01582

BruAb2_0498

glutamine synthetase family protein

SMc01594

BruAb2_0499

conserved hypothetical protein

SMc01600

BruAb2_0500

iron compound ABC transporter, ATP-binding protein, hypothetical

SMc01608

BruAb2_0529

RibH-2, riboflavin synthase, beta subunit

SMc01609

BruAb2_0535

 

Ade, adenine deaminase

SMc01533

BruAb2_0573

renal dipeptidase family protein

SMc01524

BruAb2_0572

 

hypothetical FrnE

SMc00952

BruAb2_0647

peptide ABC transporter, periplasmic peptide-binding protein

SMc00951

BruAb2_0648

conserved hypothetical protein

SMc00950

BruAb2_0649

conserved hypothetical protein

SMc00949

BruAb2_0650

 

oxidoreductase, Gfo/Idh/MocA family

SMc02870

BruAb2_0703

sugar ABC transporter, permease protein

SMc02871

BruAb2_0704

sugar ABC transporter, permease protein

SMc02872

BruAb2_0705

conserved hypothetical protein

SMc02875

BruAb2_0708

transcriptional regulator, GntR family

SMc02876

BruAb2_0709

NagB glucosamine-fructose-6-phosphate aminotransferase

SMc02877

BruAb2_0321

NagA N-acetylglucosamine-6-phosphate deacetylase

SMc02878

BruAb2_0322

 

hypothetical glyoxalase

SMc04054

BruAb2_0742

transcriptional regulator, MarR family

SMc04052

BruAb2_0743

 

50S ribosomal protein L34

SMc04434

BruAb2_0961

RnpA, ribonuclease P, protein component

SMc01720

BruAb2_0962

inner-membrane protein, 60 kDa

SMc01721

BruAb2_0963

hypothetical GTP-binding protein

SMc01722

BruAb2_0964

hydrolase, haloacid dehalogenase-like family

SMc01730

BruAb2_0966

conserved hypothetical protein TIGR00730, hypothetical

SMc01731

BruAb2_0967

 

DapE, succinyl-diaminopimelate desuccinylase

SMc01096

BruAb2_0971

TruA, tRNA pseudouridine synthase A

SMc01099

BruAb2_0973

Fmt, methionyl-tRNA formyltransferase

SMc01100

BruAb2_0974

Def-2, polypeptide deformylase

SMc01101

BruAb2_0975

conserved hypothetical protein

SMc01102

BruAb2_0976

 

glutathione S-transferase family protein

SMc00407

BruAb2_0984

hypothetical iron-sulfur cluster-binding protein

SMc00406

BruAb2_0985

conserved hypothetical protein

SMc00405

BruAb2_0986

 

MepA, penicillin-insensitive murein endopeptidase

SMc02833

BruAb2_0987

MgsA, methylglyoxal synthase

SMc02834

BruAb2_0988

Glk, glucokinase

SMc02835

BruAb2_0989

ABC transporter, ATP-binding/permease protein

SMc02836

BruAb2_0990

DapB, dihydrodipicolinate reductase

SMc02837

BruAb2_0991

Gpm, phosphoglycerate mutase

SMc02838

BruAb2_0992

 

ubiquinone biosynthesis protein UbiB

SMc01156

BruAb2_1005

ubiquinone/menaquinone biosynthesis methlytransferase UbiE

SMc01155

BruAb2_1006

 







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Table S9. First gene cluster: shared by chromosome II in Agrobacterium strains and by pSymB in Sinorhizobium meliloti. This gene cluster most likely moved from the ancestral chromosome I onto the pSymB precursor before the split of the Sinorhizobium lineage away from the rest of the Rhizobiaceae lineage. Remaining gene clusters: shared by chromosome I in Agrobacterium strains (extant examples of ancestral chromosome I) and by pSymB in Sinorhizobium meliloti. These gene clusters most likely moved from the ancestral chromosome I onto the pSymB precursor after the split of the Sinorhizobium lineage away from the rest of the Rhizobiaceae lineage.

 

 

Product

Gene ID

 

C58

S4

K84

S. meliloti

transcriptional regulator, AraC family

atu4659

avi5122

arad9546

SM_b21649

alpha-galactosidase

atu4660

avi5121

arad9545

SM_b21648

ABC transporter

atu4661

avi5120

arad9544

SM_b21647

ABC transporter

atu4662

avi5118

arad9543

SMb21646

ABC transporter

atu4663

avi5117

arad9540

SM_b21645

ABC transporter

atu4664

avi5116

arad9539

SM_b21644

alpha-galactosidase

 

atu4665

avi5115

arad9538

SM_b21643

 

 

 

 

 

 

 

 

 

 

transcriptional regulator

Atu0235

Avi2977

Arad4508

SM_b20039

hypothetical transmembrane protein

Atu0234

Avi2978

Arad4509

SM_b20040

 

transcriptional regulator, GntR or ArsR family

Atu0182

Avi0266

Arad0293

SM_b20758

C-P (carbon-phosphorus lyase component

Atu0181

Avi0267

Arad0292

SM_b20759

PhnH C-P (carbon-phosphorus) lyase component

Atu0180

Avi0269

Arad0291

SM_b20760

PhnI C-P (carbon-phosphorus) lyase component

Atu0179

Avi0270

Arad0289

SM_b20761

PhnJ C-P (carbon-phosphorus) lyase component

Atu0178

Avi0273

Arad0288

SM_b20762

PhnK phosphonate ABC transporter, ATP-binding subunit

Atu0177

Avi0274

Arad0287

SM_b20763

PhnL phosphonate ABC transporter, ATP-binding subunit

Atu0176

Avi0275

Arad0285

SM_b20764

acetyltransferase

Atu0175

Avi0277

Arad0283

SM_b20765

 

conserved hypothetical protein

Atu2267

a

Arad4851

SM_b20532

ECF family sigma factor

Atu2268

a

Arad4853

SM_b20531

 

a These genes appear to have been lost from the genome.

 

 







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Table S10. Key gene clusters shared by chromosome I in S. meliloti (extant examples of ancestral chromosome I), chromosome II in biovar 1 (C58) and 3 (S4) strains of Agrobacterium, the 2651 kbp replicon in biovar 2 (K84) of Agrobacterium, plasmid p42e of Rhizobium etli (Ret), and plasmid pRL11 of Rhizobium leguminosarum (Rleg), most likely due to an ancestral intragenome gene transfer from chromosome I to a repABC-type IRT plasmid in the Agrobacterium/Rhizobium lineage.

 

Product

Gene ID

 

S. meliloti

C58

S4

K84

R. etli

R. legum

ABC transporter [sugar]

 

 

 

 

 

 

     ATPase subunit
SMc01980
Atu3171
a
Arad9098
RHE_PE00248
pRL110367
     permease subunit
SMc01979
Atu3172
a
Arad9096
RHE_PE00247
pRL110366
     permease subunit
SMc01978
Atu3173
a
Arad9095
RHE_PE00246
pRL110365
     periplasmic substrate-binding subunit
SMc01977
Atu3174
a
Arad9093
RHE_PE00245
pRL110364
methionine gamma-lyase
SMc01976
Atu3175
Avi5346
Arad9092
RHE_PE00244
pRL110363
GntR-type transcriptional regulator
SMc01975
Atu3176
Avi5347
Arad9091
RHE_PE00243
pRL110362

 

sarcosine oxidase alpha subunit
SMc02606
Atu4222
Avi5744
Arad8356
RHE_PE00426
pRL110562
sarcosine oxidase delta subunit
SMc02607
Atu4223
Avi5745
Arad8357
RHE_PE00425
pRL110561
sarcosine oxidase beta subunit
SMc02608
Atu4224
Avi5746
Arad8358
RHE_PE00424
pRL110560
AraC-type transcriptional regulator (glxA)
SMc02609
Atu4225
Avi5747
Arad8359
RHE_PE00423
pRL110559
transcriptional regulator
SMc02620
Atu4226
Avi5748
Arad8360
RHE_PE00422
pRL110558
amidophosphoribosyltransferase (glxB)
SMc02610
Atu4227
Avi5749
Arad8362
RHE_PE00421
pRL110557

formyl-methanofuran dehydrogenase (glxC)

SMc02611

Atu4228

Avi5750

Arad8364

RHE_PE00420

pRL110556

glutamate synthase large subunit (glxD)

SMc02612

Atu4229

Avi5751

Arad8365

RHE_PE00419

pRL110555

glutamine synthetase III

SMc02613

Atu4230

Avi5752

Arad8357

RHE_PE00418

pRL110554

 

a These genes appear to have been lost from the genome.

 







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Table S11. Key gene cluster shared by chromosome II in biovar 1 and 3 strains of Agrobacterium and by chromosome I in S. meliloti and Agrobacterium bv. 2 (K84), most likely due to an ancestral intragenome gene transfer from chromosome I to chromosome II in the lineage that includes biovars 1 and 3 after this lineage diverged away from biovar 2.

 

Product

Gene ID

 

C58 (bv 1)

S4 (bv 3)

K84 (bv 2)

S. meliloti

ABC transporter, ATPase subunit
Atu3111
Avi5585
Arad4630
SMc04140

Oxidoreductase

Atu3966

Avi5584

Arad4629

SMc04139

Oxidoreductase
Atu3965
Avi5583
Arad4627
SMc04138
ABC transporter, permease subunit
Atu3112
Avi5582
Arad4625
SMc04137
ABC transporter, permease subunit
Atu3113
Avi5581
Arad4624
SMc04136

ABC transporter, periplasmic substrate-binding subunit

Atu3114

Avi5580

Arad4622

SMc04135

Transcriptional regulator, TetR family

Atu3115

Avi6229

Arad4621

SMc04134

Oxidoreductase

Atu3116

a

Arad4620

SMc04133

Conserved hypothetical

Atu3117

a

Arad8627

SMc04132

Conserved hypothetical

Atu3118

a

Arad8628

SMc04130

Conserved hypothetical

Atu3119

Avi5579

Arad4618

SMc04129

 

a These genes appear to have been lost from the genome.

 







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Table S12. Key gene clusters shared by chromosome I in S. meliloti or Agrobacterium bv. 2 (K84) or Agrobacterium bv. 3 (S4) (extant examples of ancestral chromosome I) and by chromosome II in biovar 1 (C58), most likely due to an ancestral intragenome gene transfer from chromosome I to chromosome II in the biovar 1 lineage after it diverged from biovar 3 lineage.

 

Product

Gene ID

 

C58 (bv 1)

S4 (bv 3)

K84 (bv 2)

S. meliloti

ABC transporter, membrane protein (sorbitol/mannitol)

Atu3168 a

Avi3568

Arad4016

SMc01497

ABC transporter, membrane protein (sorbitol/mannitol)

Atu3169 a

Avi3569

Arad4014

SMc01498

ABC transporter, nucleotide binding/ATPase protein

Atu3170 a

Avi3570

Arad4012

SMc01499

 

 

 

 

 

Transcriptional regulator, luxR family

Atu3318 d

e

Arad7628

SMc03150

hypothetical protein

Atu3319

 

 

 

Fibrinogen binding protein

Atu3320 d

e

e

SMc03149

Hypothetical protein

Atu3321 d

e

e

SMc03148

ABC transporter, nucleotide binding/ATPase protein

Atu3322 d

e

e

SMc03147

secretion protein, HlyD family

Atu3323 d

e

e

SMc03146

Hypothetical protein

Atu3324 d

e

e

SMc03145

 

hypothetical protein

Atu3347

Avi2407

Arad2648

SMc04253

hypothetical protein

Atu3348

Avi2406

Arad2649

SMc04254

ABC transporter, nucleotide binding/ATPase protein

Atu3349

Avi2404

Arad2652

SMc04256

ABC transporter, membrane spanning protein

Atu3350

Avi2402

Arad2653

SMc04257

ABC transporter, membrane spanning protein (sugar)

Atu3351

Avi2400

Arad2655

SMc04258

ABC transporter, substrate binding protein (sugar)

Atu3352

Avi2399

Arad2656

SMc04259

 

secretion protein, HlyD family

Atu3382

Avi1113

Arad4713

SMc04208

rhizobicin secretion

Atu3383

Avi1114

Arad4714

SMc04207

conserved hypothetical protein

Atu3384

e

e

SMc04206

heme receptor

Atu3385

e

e

SMc04205

 

branched-chain alpha-keto acid dehydrogenase subunit E2

Atu3471 d

e

e

SMc03203

2-oxoisovalerate dehydrogenase beta subunit

Atu3472 d

e

e

SMc03202

2-oxoisovalerate dehydrogenase alpha subunit

Atu3473 d

e

e

SMc03201

 

pantoate--beta-alanine ligase

Atu3482

Avi2846

Arad2962

SMc01880

3-methyl-2-oxobutanoate hydroxymethyltransferase

Atu3483

Avi2847

Arad2963

SMc01881

 

3-demethylubiquinone-9 3-methyltransferase

Atu3508 b

Avi3965

Arad4133

SMc02440

hypothetical protein

Atu3509 b

Avi3967

Arad4135

SMc02441

amidohydrolase

Atu3510 b

Avi3968

Arad4137

SMc02442

glutaredoxin

Atu3511 b

Avi3969

Arad4139

SMc02443

competence protein F

Atu3512 b

Avi3970

Arad4141

SMc02444

methyltransferase

Atu3513 b

Avi3971

Arad4146

SMc02445

hypothetical protein

Atu3515 b

Avi3974

Arad4150

SMc02447

NTP pyrophosphohydrolase, MutT family

Atu3516 b

Avi3976

Arad4152

SMc02448 

acetyltransferase

Atu3517 b

Avi3977

Arad4153

SMc02449

ornithine acetyltransferase/N-acetylglutamate synthase

Atu3518 b

Avi3979

Arad4154

SMc02450

peptidyl-prolyl cis-trans isomerase

Atu3519 b

Avi3981

Arad4155

SMc02451

preprotein translocase SecA subunit

Atu3520 b

Avi3982

Arad4157

SMc04458

 

glutamyl-Q tRNA(Asp) synthetase

Atu3589 b

Avi4004

Arad4184

SMc00735

transporter

Atu3590 b

Avi4005

Arad4186

SMc00734

short chain dehydrogenase

Atu3591 b

Avi4006

Arad4187

SMc00733

hypothetical protein

Atu3593 b

Avi4008

Arad4189

SMc00731

hypothetical protein

Atu3594 b

e

e

SMc00730

electron transfer flavoprotein beta subunit

Atu3595 b

Avi4010

Arad4191

SMc00729

electron transfer flavoprotein alpha subunit

Atu3596 b

Avi4012

Arad4193

SMc00728

3-hydroxybutyryl-CoA dehydrogenase

Atu3597 b

Avi4015

Arad4195

SMc00727

thiol:disulfide interchange protein

Atu3599 b

Avi4017

Arad4197

SMc00725

argininosuccinate lyase

Atu3598 b

Avi4016

Arad4196

SMc00726

hypothetical protein

Atu3600 b

Avi4018

Arad4198

SMc00724

diaminopimelate decarboxylase

Atu3601 b

Avi4020

Arad4200

SMc00723

hypothetical protein

Atu3602 b

Avi4021

Arad4202

SMc00722

two component response regulator

Atu3603 b

Avi4023

Arad4317

SMc00720

hypoxanthine phosphoribosyltransferase

Atu3604 b

Avi4024

Arad4205

SMc00719

hypothetical protein

Atu3605 b

Avi4026

Arad4206

e

cell division ATP-binding protein

Atu3606 b

Avi4027

Arad4207

SMc00717

cell division protein

Atu3607 b

Avi4028

Arad4208

SMc00716

hypothetical protein

Atu3608 b

Avi4029

Arad4209

SMc00715

1-acyl-sn-glycerol-3-phosphate acyltransferase

Atu3609 b

Avi4030

Arad4211

SMc00714

transporter

Atu3610 b

Avi4031

Arad4212

SMc00713

cyclohexadienyl dehydrogenase

Atu3611 b

Avi4033

Arad4216

SMc00711

histidinol-phosphate aminotransferase

Atu3612 b

Avi4034

Arad4217

SMc00710

hypothetical protein

Atu3613 b

Avi4035

Arad4218

SMc00709

glyoxalase II

Atu3614 b

Avi4036

Arad4219

SMc00708

hypothetical protein

Atu3615 b

Avi4037

Arad4220

SMc00707

hypothetical protein

Atu3616 b

Avi4040

Arad4223

SMc00705

50S ribosomal protein L28

Atu3617 b

Avi4041

Arad4224

SMc00704

hypothetical protein

Atu3618 b

Avi4043

Arad4225

SMc00703

hypothetical protein

Atu3620 b

Avi4044

Arad4227

SMc00702

cobyrinic acid synthase

Atu3621 b

Avi4045

Arad4228

SMc00701

cobalamin biosynthesis protein

Atu3622 b

Avi4046

Arad4229

SMc00700

molecular chaperone, DnaJ family

Atu3623 b

Avi4048

Arad4231

SMc00699

stress induced morphogen

Atu3624 b

Avi4050

Arad4232

SMc00698

3-dehydroquinate synthase

Atu3625 b

Avi4051

Arad4234

SMc00696

shikimate kinase

Atu3626 b

Avi4053

Arad4236

SMc00695

hypothetical protein

Atu3628 b

Avi4054

Arad4237

SMc00692

site-specific tyrosine recombinase XerD

Atu3629 b

Avi4056

Arad4238

SMc00691

acetyl-CoA carboxylase carboxyltransferase subunit alpha

Atu3630 b

Avi4057

Arad4239

SMc00690

hypothetical protein

Atu3631 b

Avi4058

Arad4240

SMc00689

hypothetical protein

Atu3632 b

Avi4059

Arad4242

SMc00688

hypothetical protein

Atu3633 b

Avi4060

Arad4243

SMc00684

penicillin-binding protein dacf precursor

Atu3634 b

Avi4061

Arad4244

SMc00682

amidohydrolase

Atu3635 b

Avi4062

Arad4246

SMc00683

 

D-3-phosphoglycerate dehydrogenase

Atu3706 c

Avi3595

Arad3664

SMc00641

phosphoserine aminotransferase

Atu3707 c

Avi3596

Arad3666

SMc00640

outer surface protein

Atu3708 c

Avi3602

Arad3670

SMc00638

phosphoglucomutase/phosphomannomutase

Atu3709 c

Avi3629

Arad3674

SMc00637

metalloprotease

Atu3710 c

Avi3627

Arad3675

SMc04459

conserved hypothetical protein

Atu3711 c

Avi3626

Arad3676

SMc02940

hypothetical protein

Atu3712 c

Avi3624

Arad3677

SMc02941

omp16 protein

Atu3713 c

Avi3622

Arad3678

SMc02942

TolB protein

Atu3714 c

Avi3621

Arad3679

SMc04461

hypothetical protein

Atu3715 c

Avi3620

Arad3681

SMc03956

tolR protein

Atu3716 c

Avi3619

Arad3682

SMc03957

tolQ Protein

Atu3717 c

Avi3618

Arad3684

SMc03958

hypothetical protein

Atu3718 c

Avi3616

Arad3685

SMc03960

MutT/nudix family protein

Atu3719 c

Avi3611

Arad3693

SMc02448

conserved hypothetical protein

Atu3720 c

Avi3614

Arad3692

e

hypothetical protein

Atu3721

 

 

 

Holliday junction DNA helicase B

Atu3722 c

Avi3609

Arad3695

SMc03965

Holliday junction DNA helicase motor protein

Atu3723 c

Avi3605

Arad3697

SMc03966 

Holliday junction resolvase

Atu3724 c

Avi3604

Arad3699

SMc03967

methyl-accepting chemotaxis protein

Atu3725

 

 

 

flavin dependant oxidoreductase

Atu3726 c

Avi3603

Arad3701

SMc03968

hypothetical protein

Atu3727 c

Avi3631

Arad3703

SMc03969

conserved hypothetical protein

Atu3728 c

Avi3632

e

e

hypothetical protein

Atu3729 c

Avi3633

Arad3704

SMc03970

hypothetical protein

Atu3730 c

Avi3650

Arad3706

SMc03973

5-formyltetrahydrofolate cyclo-ligase

Atu3731 c

Avi3649

Arad3708

SMc03974

hemolysin

Atu3732 c

Avi1919

Arad2040

SMc00240

hypothetical protein

Atu3733

 

 

 

conserved hypothetical protein

Atu8191 c

Avi3642

Arad3724

SMc03976

conserved hypothetical protein

Atu8192 c

Avi3640

Arad3726

SMc03977

transketolase

Atu3736 c

Avi3638

Arad3727

SMc03978

Glyceraldehyde 3-Phosphate Dehydrogenase

Atu3737 c

Avi3637

Arad3729

SMc03979

Na+/H+ antiporter

Atu3738 c

Avi3634

Arad3731

e

phosphoglycerate kinase

Atu3739 c

Avi3651

Arad3732

SMc03981

fructose bisphosphate aldolase

Atu3740 c

Avi3652

Arad3734

SMc03983

MFS permease

Atu3741 c

Avi3661

Arad3741

SMc03987

hypothetical protein

Atu3742 c

Avi3663

Arad3745

SMc03989

50S ribosomal protein L31

Atu3743 c

Avi3665

Arad3749

SMc03990

ABC transporter, nucleotide binding/ATPase protein

Atu3744 c

Avi3667

Arad3750

SMc03991

conserved hypothetical

Atu3745 c

Avi3668

Arad9600

e

hypothetical protein

Atu3746 c

Avi3670

Arad3755

SMc03992

hypothetical protein

Atu3747 c

Avi3671

Arad3757

SMc03993

extragenic suppressor protein SuhB

Atu3748 c

Avi3672

Arad3759

SMc03994

enhanced entry protein

Atu3749 c

Avi3674

Arad3763

SMc03995

thiamine-phosphate pyrophosphorylase

Atu3750 c

Avi3675

Arad3764

SMc03996

hypothetical protein

Atu3751 c

Avi3677

e

SMc03997

conserved hypothetical protein

Atu3752

 

 

 

hypothetical protein

Atu3753 c

Avi3681

Arad3768

SMc04000

phosphoribosylaminoimidazole carboxylase catalytic subunit

Atu3754 c

Avi3683

Arad3770

SMc04001

phosphoribosylaminoimidazole carboxylase ATPase subunit

Atu3755 c

Avi3684

Arad3771

SMc04002

hypothetical protein

Atu8067 c

Avi3686

Arad3772

SMc04003

hypothetical protein

Atu3757 c

Avi3687

Arad3773

SMc04004

hypothetical protein

Atu3758 c

Avi3695

Arad3789

SMc04009

hypothetical protein

Atu3759 c

Avi3693

Arad3787

SMc04008

hypothetical protein

Atu3760 c

Avi3692

Arad3786

SMc04007

hypothetical protein

Atu3761 c

Avi3691

Arad3784

SMc04006

pyruvate kinase

Atu3762 c

Avi3690

Arad3783

SMc04005

hypothetical protein

Atu3763 c

Avi3698

Arad3804

SMc04010

sigma 54 dependent transcriptional activator

Atu3764 c

Avi3699

Arad3805

SMc04011

oligoendopeptidase F

Atu3765 c

Avi3702

Arad3807

SMc04012

hypothetical protein

Atu3766 c

Avi3704

Arad3809

SMc04014

GGDEF family protein

Atu3767 c

e

e

SMc04015

homospermidine synthase

Atu3768 c

Avi3707

Arad3814

SMc04016

outer membrane lipoprotein

Atu3769 c

Avi3710

Arad3816

SMc04017

5'-nucleotidase

Atu3770 c

Avi3711

Arad3820

SMc04018

ferrochelatase

Atu3771 c

Avi3712

Arad3821

SMc04019

hypothetical protein

Atu3772 c

Avi3720

Arad3825

SMc04020

hypothetical protein

Atu3773 c

Avi3721

Arad3826

SMc04021

capsule expression protein

Atu3774 c

Avi3722

Arad3827

SMc02268

Conserved hypothetical protein

Atu3775

 

 

 

hypothetical protein

Atu3776

 

 

 

hypothetical protein

Atu3777 c

Avi3723

Arad3828

SMc04022

UTP-glucose-1-phosphate uridylyltransferase

Atu3778 c

Avi3724

Arad3829

SMc04023

lytic murein transglycosylase

Atu3779 c

Avi3727

Arad0178

SMc04024

hypothetical protein

Atu3780 c

Avi3728

Arad3831

SMc04025

two component response regulator

Atu3781

 

 

 

two component sensor kinase

Atu3782

 

 

 

glutamate synthase subunit beta

Atu3783 c

Avi3730

Arad3834

SMc04026

glutamate synthase large subunit

Atu3784 c

Avi3734

Arad3836

SMc04028

threonine aldolase

Atu3785 c

Avi3736

Arad3838

SMc04029

 

chemotaxis response regulator

Atu3883 d

Avi3746

Arad3856

SMc04044

hypothetical protein

Atu3884 d

Avi3744

Arad3854

SMc04043

inositol monophosphatase family protein

Atu3885 d

Avi3743

Arad3852

SMc04042

lysophospholipase

Atu3886 d

Avi3740

Arad3851

SMc04041

small heat shock protein

Atu3887 d

Avi3739

Arad3843

SMc04040

hypothetical protein

Atu3888 d

Avi5029

Arad3842

SMc04030

transcriptional regulator, LysR family

Atu3889 d

e

Arad3841

e

 

hypothetical protein

Atu3891 d

Avi0100

Arad4610

SMc02514

hypothetical protein

Atu3892 d

Avi0099

Arad4609

SMc02515

ABC transporter, membrane spanning protein (sugarl)

Atu3893 d

Avi0098

Arad4608

SMc02516

ABC transporter, membrane spanning protein (sugar)

Atu3894 d

Avi0097

Arad4608

SMc02517

ABC transporter, nucleotide binding/ATPase protein (sugar)

Atu3895 d

Avi0096

Arad4605

SMc02518

ABC transporter, nucleotide binding/ATPase protein (sugar)

Atu3896 d

Avi0095

Arad4604

SMc02519

glycerol-3-phosphate dehydrogenase

Atu3897 d

Avi0094

Arad4294

SMc02520

transcriptional regulator, DeoR family

Atu3898 d

Avi0092

Arad4293

SMc02521

 

O-linked GlcNAc transferase

Atu4063 c

Avi3772

Arad3887

SMc03935

30S ribosomal protein S21

Atu4064 c

Avi3775

Arad3885

SMc03934

hypothetical protein

Atu4065

 

 

 

sarcosine oxidase beta subunit

Atu4066 c

Avi3774

Arad3882

SMc03933

conserved hypothetical protein

Atu4067 c

e

Arad3881

e

sarcosine oxidase delta subunit

Atu4068 c

Avi3776

Arad3879

SMc03932

sarcosine oxidase alpha subunit

Atu4069 c

Avi3777

Arad3878

SMc03931

sarcosine oxidase gamma subunit

Atu4070 c

Avi3778

Arad3877

SMc03930

hypothetical protein

Atu4071 c

Avi3766

e

SMc03928

nodulation protein N

Atu4072 c

Avi3765

Arad3875

SMc03927

glycogen debranching enzyme

Atu4073 c

Avi3764

Arad3874

SMc03926

phosphoglucomutase

Atu4074 c

Avi3763

Arad3873

SMc03925

glycogen synthase

Atu4075 c

Avi3762

Arad3872

SMc03924

glucose-1-phosphate adenylyltransferase

Atu4076 c

Avi3761

Arad3871

SMc03923

glycogen branching enzyme

Atu4077 c

Avi3760

Arad3869

SMc03922

glycogen phosphorylase

Atu4078 c

Avi3758

Arad3868

SMc04460

 

cytidylate kinase

Atu4103

Avi0193

Arad0143

SMc00334

30S ribosomal protein S1

Atu4104

Avi0194

Arad0142

SMc00335

hypothetical protein

Atu4105

Avi0130

Arad0141

e

 

UDP-glucuronic acid epimerase

Atu4148

Avi3924

Arad3521

SMc02640

UDP-glucose 6-dehydrogenase

Atu4149

Avi1502

Arad3519

SMc02641

 

aspartate kinase

Atu4172 b

Avi3957

Arad4131

SMc02438

phosphoenolpyruvate-protein phosphotransferase

Atu4173 b

Avi3956

Arad4130

SMc02437

peptide chain release factor 1

Atu4174 b

Avi3955

Arad4128

SMc02436

protoporphyrinogen oxidase

Atu4175 b

Avi3954

Arad4127

SMc02435

hypothetical protein

Atu4176b

Avi3953

Arad4126

SMc02434

ATP-dependent Clp protease, ATP-binding subunit

Atu4177 b

Avi3951

Arad4124

SMc02433

conserved hypothetical protein

Atu4178 b

Avi3949

Arad4121

SMc02432

 

hypothetical protein

Atu4446 a

Avi3563

Arad4019

SMc01495

ABC transporter, substrate binding protein (sorbitol)

Atu4447 a

Avi3567

Arad4017

SMc01496

ABC transporter, membrane spanning protein

Atu4448 a

Avi3568

Arad4016

SMc01497

ABC transporter, membrane spanning protein

Atu4449 a

Avi3569

Arad4014

SMc01498

ABC transporter, nucleotide binding/ATPase protein (sugar)

Atu4450 a

Avi3570

Arad4012

SMc01499

mannitol 2-dehydrogenase

Atu4451 a

Avi3572

Arad4011

SMc01501

hypothetical protein

Atu4452 a

Avi3573

Arad4010

SMc01502

ribitol kinase

Atu4453 a

Avi3574

Arad4009

SMc01503

transcriptional regulator, RpiR family

Atu4454 a

e

Arad4008

e

conserved hypothetical protein

Atu4456 a

Avi3841

Arad4006

SMc02882

endonuclease III

Atu4457 a

Avi3842

Arad4005

SMc02843

hypothetical protein

Atu4458 a

Avi3844

Arad4004

SMc02842

6-O-methylguanine-DNA methyltransferase

Atu4459 a

Avi3845

Arad4003

SMc02841

 

hypothetical protein

Atu4472

Avi3855

Arad3963

SMc03174

lysyl-tRNA synthetase

Atu4473 c

Avi3856

Arad3954

SMc03173

glutamyl-tRNA synthetase

Atu4474 c

Avi3858

Arad3953

SMc03172

transporter

Atu4475 c

Avi3860

e

SMc04179

hypothetical protein

Atu4476 c

Avi3839

Arad3947

SMc03171

transcriptional regulator, TetR family

Atu4477 c

Avi3838

Arad3945

SMc03169

multidrug resistance efflux pump

Atu4478 c

Avi3837

Arad3944

SMc03168

MFS permease

Atu4479 c

Avi3836

Arad3942

SMc03167

conserved hypothetical protein

Atu4480

 

 

 

transcriptional regulator, LacI family

Atu4481 c

Avi3834

Arad3940

SMc03165

xylulokinase

Atu4482 c

Avi3833

Arad3939

SMc03164

xylose isomerase

Atu4483 c

Avi3832

Arad3938

SMc03163

hypothetical protein

Atu4484

 

 

 

beta-glucosidase

Atu4485 c

Avi3827

Arad3925

SMc03160

nitroreductase

Atu4486 c

Avi1179f

e

e

ABC transporter, nucleotide binding/ATPase protein

Atu4487 c

Avi7230

Arad3603

SMc03159

ABC transporter, membrane spanning protein

Atu4488 c

Avi7231

Arad3604

SMc03158

outer membrane lipoprotein

Atu4489 c

Avi7233

Arad3600

SMc03157

GGDEF family protein

Atu4490 c

Avi5602

Arad3923

e

hypothetical protein

Atu4491 c

Avi3823

Arad3921

SMc03156

hypothetical protein

Atu4492 c

Avi3820

Arad3920

SMc03155

hypothetical protein

Atu4493 c

Avi3819

Arad3919

SMc03154

keto-hydroxyglutarateketo-deoxy-phosphogluconate aldolase

Atu4494 c

Avi3816

Arad3917

SMc03153

hypothetical protein

Atu4495 c

Avi3814

Arad3925

SMc03152

acetyltransferase

Atu4496 c

Avi3813

Arad3390

SMc03151

hypothetical protein

Atu4497 c

Avi3812

Arad3915

SMc02989

hypothetical protein

Atu4498 c

Avi3811

Arad3914

SMc02986

hypothetical protein

Atu4499 c

Avi3809

Arad3913

SMc02985

hypothetical protein

Atu4501 c

Avi3798

Arad3905

SMc02979

cobalamin synthesis protein

Atu4502 c

Avi3796

Arad3903

SMc02978

transcriptional regulator, MarR family

Atu4504 c

Avi3793

Arad3901

SMc02976

creatinine amidohydrolase

Atu4503 c

Avi3547

Arad3523

SMc02977

transcriptional regulator, LacI family

Atu4505 c

Avi3792

Arad3900

SMc02975

 

hypothetical protein

Atu4509

Avi0080

Arad1555

SMc00432

hypothetical protein

Atu4510

Avi0078

Arad1557

SMc00433

acetolactate synthase

Atu4511

Avi0077

Arad1558

SMc01166

myo-inositol catabolism IolC protein

Atu4512

Avi0076

Arad1559

SMc01165

 

transcriptional regulator, LysR family

Atu4705 d

Avi4101

Arad4288

SMc02523

formate dehydrogenase subunit gamma

Atu4706 d

Avi4099

Arad4287

SMc02524

NADH ubiquinone oxidoreductase chain F

Atu4707 d

Avi4098

Arad4286

SMc02525

formate dehydrogenase alpha subunit

Atu4708 d

Avi4097

Arad4285

SMc04444

formate dehydrogenase delta subunit

Atu4709 d

Avi4095

Arad4282

SMc03086

MFS permease

Atu4710 d

Avi4093

Arad4281

e

 

a part of a ~38 kbp transfer from chromosome I (positions 2603823 to 2635533 on S. meliloti chromosome I)

b part of a ~219 kbp transfer from chromosome I (positions 2699551 to 2918883 on S. meliloti chromosome I)

c part of a ~201 kbp transfer from chromosome I (positions 2935226 to 3136047 on S. meliloti chromosome I)

d part of a ~124 kbp transfer from chromosome I (positions 3163235 to 3287471 on S. meliloti chromosome I)

e appears to have been lost from the genome

f appears to have moved again to another component of the genome

 

 

 







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Table S13. Key gene cluster shared by chromosome I in Agrobacterium biovar 1 (extant example of ancestral chromosome) and by the 2651 kbp replicon in biovar 2 (K84) of Agrobacterium, plasmid p42e of Rhizobium etli (Ret), and plasmid pRL11 of Rhizobium leguminosarum (Rleg), most likely due to an ancestral intragenome gene transfer from chromosome I to the repABC-type IRT plasmid in the biovar 2 lineage after it diverged from the biovar 1/biovar 3 lineage.

 

Product

Gene ID

 

K84 (bv 2)

R. etli

R. legume

C58 (bv 1)

precorrin-4 C11-methyltransferase protein

Arad9589

RHE_PE00449

pRL110625

Atu2796

precorrin-6Y C5,15-methyltransferase (decarboxylating) protein

Arad9591

RHE_PE00450

pRL110626

Atu2798

precorrin 6x reductase protein

Arad9592

RHE_PE00451

pRL110627

Atu2799

precorrin-3B C17-methyltransferase protein

Arad9593

RHE_PE00452

pRL110628

Atu2800

precorrin-2 c20-methyltransferase protein

Arad9594

RHE_PE00453

pRL110629

Atu2801

precorrin-8x Methylmutase protein

Arad9595

RHE_PE00454

pRL110630

Atu2802

 

 







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Table S14. Key gene clusters shared by chromosome II of all sequenced Vibrio strains (Vibrio cholerae O1 biovar eltor strain N16961 used as an example) and chromosome II of Photobacterium profundum, but not by chromosome I of Aeromonas hydrophila (extant representative of ancestral chromosome I), indicative of the plasmid progenitor of chromosome II. This plasmid would have entered the common ancestor prior to the divergence of the Vibrio and Photobacterium clades.

 

Product

Gene ID

 

V. cholerae

P. profundum

conserved hypothetical protein

VC_A_43

PRPRB_820

putative membrane protein

VC_A_40

PRPRB_747

hypothetical protein

VC_A_39

PRPRB_746

 

hypothetical protein

VC_A_4

PRPPB_1769

hypothetical protein

VC_A_3

PRPRB_792

RctB replication protein

VC_A_2

PRPRB_1

ParB family protein

VC_A_1114

PRPRB_2024

 

hypothetical protein

VC_A_922

PRPRB_376

lipoprotein

VC_A_920

PRPRB_1176

TetR family transcription factor

VC_A_917

PRPRB_1177

 

 

 

CreA protein

VC_A_800

PRPRB _517

hypothetical protein

VC_A_799

PRPRB_787

 

 

 

hypothetical protein

VC_A_571

PRPRB _930

hypothetical protein

VC_A_579

PRPRB _663

 

 

 

Molybdenum ABC transport periplasmid binding protein

VC_A_726

PRPRB _1349

Cobyric acid synthase

VC_A_727

PRPRB _991

 

 

 

conserved hypothetical protein

VC_A_208

PRPRB _912

ammonia-dependent NAD(+) synthetase

VC_A_207

PRPRB _911

 

 







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Table S15. Key gene clusters shared by chromosome I of Aeromonas hydrophila (extant representative of ancestral chromosome I) and by chromosome II of all sequenced Vibrio strains (Vibrio cholerae O1 biovar eltor strain N16961 used as an example) and chromosome II of Photobacterium profundum. These gene clusters are presumed to have moved from the ancestral chromosome I to the plasmid-derived chromosome II prior to the divergence of the Vibrio and Photobacterium clades.

 

Product

Gene ID

 

A. hydrophila

V. cholerae

P. profundum

NrdD anaerobic ribonucleoside-triphosphate reductase

AHA_1231

VC_A_511

PRPRB_442

NrdG anaerobic ribonucleoside-triphosphate reductase activating protein

AHA_1232

VC_A_512

PRPRB_443

 

maltose-binding periplasmic protein

AHA_1667

VC_A_945

PRPRB_421

MalF maltose transport system permease protein

AHA_1668

VC_A_944

PRPRB_422

MalG maltose transport system permease protein

AHA_1669

VC_A_943

PRPPB_423

MalK maltose/maltodextrin import ATP-binding protein

AHA_1670

VC_A_946

PRPRB_420

 

HlyD family secretion protein

AHA_2700

VC_A_1080

PRPRB_584

toxin secretion ATP-binding protein

AHA_2701

VC_A_1084

PRPRB_579

 

UhpA transcriptional regulatory protein

AHA_2796

VC_A_682

PRPRB_378

UhpC regulatory protein

AHA_2798

VC_A_684

PRPRB_376

 

MarR family transcriptional regulator

AHA_3609

VC_A_1005

PRPRB_1176

organic hydroperoxide reductase

AHA_3610

VC_A_1006

PRPRB_1177

 

PntB NAD(P) transhydrogenase, beta subunit

AHA_4079

VC_A_564

PRPRB _903

PntA NAD(P) transhydrogenase, alpha subunit

AHA_4080

VC_A_563

PRPRB_902

 







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Table S16. Key gene clusters shared by chromosome I of Aeromonas hydrophila (extant representative of ancestral chromosome I) and by chromosome II of all sequenced Vibrio strains (Vibrio cholerae O1 biovar eltor strain N16961 used as an example), but not shared by chromosome II of Photobacterium profundum. These gene clusters are presumed to have moved from the ancestral chromosome I to the plasmid-derived chromosome II in the Vibrio lineage after its divergence from the Photobacterium clade.

 

 

Product

Gene ID

 

A. hydrophila

V. cholerae

conserved hypothetical protein

AHA_1099

VC_A_55

PhrB deoxyribodipyrimidine photolyase

AHA_1101

VC_A_57

 

GGDEF domain protein

AHA_1796

VC_A_190

response regulator

AHA_1797

VC_A_189

 

FruA PTS system fructose-specific IIBC component

AHA_2346

VC_A_516

1-phosphofructokinase

AHA_2347

VC_A_517

multiphosphoryl transfer protein

AHA_2348

VC_A_518

FruR fructose repressor

AHA_2349

VC_A_519

 

YiaW inner membrane protein

AHA_2621

VC_A_48

trans-2-enoyl-CoA reductase

AHA_2629

VC_A_47

conserved hypothetical protein

AHA_1099

VC_A_55

 

MoxR protein

AHA_3136

VC_A_175

uridine phosphorylase

AHA_3168

VC_A_134

cAMP-binding protein

AHA_3169    

VC_A_135

 

ABC transporter ATP-binding protein

AHA_3488

VC_A_782

acyl-CoA thioesterase I

AHA_3489    

VC_A_783

 

Kbl 2-amino-3-ketobutyrate coenzyme A ligase

AHA_4234    

VC_A_886

Tdh L-threonine 3-dehydrogenase

AHA_4235    

VC_A_885

 

 







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Table S17. Key gene clusters shared by chromosome I of Aeromonas hydrophila (extant representative of ancestral chromosome I) and by chromosome II of Photobacterium profundum, but not shared by chromosome II of sequenced Vibrio strains (Vibrio cholerae O1 biovar eltor strain N16961 used as an example). These gene clusters are presumed to have moved from the ancestral chromosome I to the plasmid-derived chromosome II in the Photobacterium lineage after its divergence from the Vibrio clade.

 

Product

Gene ID

 

A. hydrophila

P. profundum

sensor histidine kinase

AHA_0066

PRPRB_1913

response regulator receiver domain

AHA_0067

PRPRB_1914

YhjX inner membrane protein

AHA_0068

PRPRB_1915

 

endoribonuclease L-PSP

AHA_0132

PRPRB_1933

ABC-type sugar transport system, periplasmic component

AHA_0135

PRPRB_1906

signal transduction histidine kinase

AHA_0136

PRPRB_1907

GltR transcriptional regulator

AHA_0137

PRPRB_1908

 

YeiG esterase

AHA_0213

PRPRB_1568

LysR-type transcriptional regulator

AHA_0215

PRPRB_1569

 

KefB glutathione-regulated potassium-efflux system protein

AHA_0342

PRPRB_550

modulator of glutathione-dependent potassium efflux system

AHA_0343

PRPRB_548

 

HlyD family secretion protein

AHA_0355

PRPRB_1862

LysR-type transcriptional regulator

AHA_0356

PRPRB_1860

 

class II aldolase, tagatose bisphosphate family

AHA_0805

PRPRB_1043

NagA-1 N-acetylglucosamine-6-phosphate deacetylase

AHA_0806

PRPRB_1042

N-acetyl-galactosamine ???

AHA_0807

PRPRB_1041

N-acetylgalactosamine permease IID component

AHA_0808

PRPRB_1040

N-acetylgalactosamine permease IIC component 1

AHA_0809

PRPRB_1039

N-acetylgalactosamine phosphotransferase enzyme IIB component2

AHA_0810

PRPRB_1038

D-tagatose-bisphosphate aldolase, class II, non-catalytic subunit

AHA_0812

PRPRB_1037

glucitol operon repressor

AHA_0813

PRPRB_1035

 

YhaO inner membrane transport protein

AHA_1617

PRPRB_242

conserved hypothetical protein

AHA_1619

PRPRB_240

 

periplasmic binding protein

AHA_1964

PRPRB_1817

ABC iron chelate uptake transporter, ATP-binding protein

AHA_1666

PRPRB_1814

ABC iron chelate uptake transporter permease protein

AHA_1967

PRPRB_1815

ABC iron chelate uptake transporter permease protein

AHA_1968

PRPRB_1816

TonB-dependent siderophore receptor

AHA_1969

PRPRB_1825

 

electron transfer flavoprotein beta-subunit

AHA_1976

PRPRB_1098

electron transfer flavoprotein alpha-subunit

AHA_1977

PRPRB_1097

 

MerR-type transcriptional regulator

AHA_2073

PRPRB_1113

hydroxymethylglutaryl-CoA lyase

AHA_2074

PRPRB_1119

enoyl-CoA hydratase/isomerase family protein

AHA_2076

PRPRB_1118

methylcrotonoyl-CoA carboxylase beta chain

AHA_2077

PRPRB_1115

isovaleryl-CoA dehydrogenase 2

AHA_2078

PRPRB_1114

MmsA-2 methylmalonate-semialdehyde dehydrogenase

AHA_2079

PRPRB_1111

acyl-CoA dehydrogenase family member

AHA_2080

PRPRB_1110

3-hydroxybutyryl-CoA dehydratase

AHA_2081

PRPRB_1109

MmsB 3-hydroxyisobutyrate dehydrogenase

AHA_2083

PRPRB_1107

3-oxoacyl-[acyl-carrier-protein] reductase

AHA_2084

PRPRB_1106

 

PrpB methylisocitrate lyase

AHA_2265

PRPRB_235 

2-methylcitrate synthase

AHA_2266

PRPRB_236

PrpD 2-methylcitrate dehydratase

AHA_2267

PRPRB_237

 

dimodular nonribosomal peptide synthetase

AHA_2473

PRPRB_1818

nonribosomal peptide synthetase

AHA_2474

PRPRB_1819

2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase

AHA_2475

PRPRB_1820

nonribosomal peptide synthetase

AHA_2476

PRPRB_1821

isochorismatase

AHA_2477

PRPRB_1822

2,3-dihydroxybenzoate-AMP ligase

AHA_2478

PRPRB_1823

isochorismate synthases

AHA_2479

PRPRB_1824

 

conserved hypothetical protein

AHA_2544

PRPRB_1033

conserved hypothetical protein

AHA_2545

PRPRB_1027

hypothetical membrane protein

AHA_2546

PRPRB_1032

amine oxidase, flavin-containing superfamily

AHA_2547

PRPRB_1031

conserved hypothetical protein

AHA_2548

PRPRB_1030

conserved hypothetical protein

AHA_2549

PRPRB_1029

 

MaiA maleylacetoacetate isomerase

AHA_2660

PRPRB_1167

fumarylacetoacetate hydrolase family protein

AHA_2661

PRPRB_1166

HmgA homogentisate 1,2-dioxygenase

AHA_2662

PRPRB_1165

HppD 4-hydroxyphenylpyruvate dioxygenase

AHA_2663

PRPRB_1180

 

pyruvate dehydrogenase, dihydrolipoamide acyltransferase component

AHA_2865

PRPRB_1096

pyruvate dehydrogenase E1 component, beta subunit

AHA_2866

PRPRB_1095

pyruvate dehydrogenase E1 component, alpha subunit

AHA_2867

PRPRB_1094

 

ViuB vibriobactin utilization protein

AHA_2992

PRPRB_1812

phospho-2-dehydro-3-deoxyheptonate aldolase

AHA_2993

PRPRB_1813

 

LysR-type transcriptional regulator

AHA_3112

PRPRB_1787

PurA adenylosuccinate synthetase

AHA_3113

PRPRB_1785

 

TtrA

AHA_3285

PRPRB_3

tetrathionate reductase, subunit B

AHA_3287

PRPRB_6

two component system histidine kinase

AHA_3288

PRPRB_7

FixJ transcriptional regulator

AHA_3289

PRPRB_8

 

glycine betaine/L-proline ABC transporter, permease protein

AHA_3375

PRPRB_1789

glycine betaine/L-proline ABC transporter, ATP binding protein

AHA_3376

PRPRB_1788

 

3-oxoacyl-[acyl-carrier-protein] synthase II

AHA_3382

PRPRB_104

4-hydroxybenzoyl-CoA thioesterase domain protein

AHA_3389

PRPRB_111

phenylalanine and histidine ammonia-lyase

AHA_3390

PRPRB_112

glycosyl transferase, group 2 family protein

AHA_3391

PRPRB_113

3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase

AHA_3392

PRPRB_114

acyl carrier protein

AHA_3395

PRPRB_117

putative acyl carrier protein

AHA_3396

PRPRB_118

conserved hypothetical protein                                                

AHA_3399

PRPRB_121

SAM-dependent methyltransferase

AHA_3400

PRPRB_122

 

TolR

AHA_3435

PRPRB_1219

TonB system transport protein ExbB2

AHA_3436

PRPRB_1220

biopolymer transport exbD2 protein

AHA_3437

PRPRB_1218

 

ABC-type multidrug transport system, permease component

AHA_3506

PRPRB_516

ABC-type multidrug transport system, permease component

AHA_3507

PRPRB_515

membrane-fusion protein

AHA_3508

PRPRB_514

outer membrane efflux protein                                                 

AHA_3509

PRPRB_513

 

LysR-type transcriptional regulator

AHA_3731

PRPRB_1802

transporter, drug/metabolite exporter family

AHA_3732

PRPRB_1803

 

paraquat-inducible protein B

AHA_3795

PRPRB_1160

paraquat-inducible protein A

AHA_3796

PRPRB_1161

 

ABC transporter substrate-binding protein

AHA_3983

PRPRB_175

conserved hypothetical protein                                                

AHA_3984

PRPRB_176

ABC transporter permease protein

AHA_3985

PRPRB_177

ABC transporter permease protein

AHA_3986

PRPRB_178

 

DhaM dihydroxyacetone kinase, phosphotransferase subunit

AHA_4006

PRPRB_217

dihydroxyacetone kinase, L subunit

AHA_4007

PRPRB_218

DhaK dihydroxyacetone kinase, DhaK subunit

AHA_4008

PRPRB_219

 

two-component system, regulatory protein

AHA_4052

PRPRB_844

conserved hypothetical protein                                                

AHA_4053

PRPRB_845

 

TonB-2 outer membrane receptor-mediated transport energizer protein

AHA_4248

PRPRB_1217

ExbD2 biopolymer transport protein

AHA_4249

PRPRB_1218

TonB system biopolymer transport component

AHA_4250

PRPRB_1219

TonB system biopolymer transport component

AHA_4251

PRPRB_1219

 

AtpC ATP synthase F1, epsilon subunit

AHA_4261

PRPRB_137

AtpD ATP synthase F1, beta subunit

AHA_4262

PRPRB_136

AtpG ATP synthase F1, gamma subunit

AHA_4263

PRPRB_135

AtpA ATP synthase F1, alpha subunit

AHA_4264

PRPRB_134

AtpH ATP synthase F1, delta subunit

AHA_4265

PRPRB_133

AtpF ATP synthase F0, B subunit

AHA_4266

PRPRB_132

AtpE ATP synthase F0, C subunit

AHA_4267

PRPRB_131

AtpB ATP synthase F0, A subunit

AHA_4268

PRPRB_130

 

 







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Table S18. Key gene clusters shared by chromosome II of all sequenced Burkholderia strains (Burkholderia cenocepacia AU1054 used as an example) and chromosome II of all sequenced Ralstonia strains (Ralstonia eutropha JMP134 used as an example), but not by chromosome I of Bordetella bronchiseptica RB50 (extant representative of ancestral chromosome I), indicative of the plasmid progenitor of chromosome II. This plasmid would have entered the common ancestor prior to the divergence of the Burkholderia and Ralstonia clades.

 

Product

Gene ID

 

B. cenocepacia

R. eutropha

Major facilitator superfamily member

Bcen_3861

Reut_B4859

NirD nitrite reductase NADPH oxidoreductase subunit

Bcen_3864

Reut_B4861

 

OsmC family protein

Bcen_4500

Reut_B5559

MarR family transcription factor

Bcen_4499

Reut_B5560

transglutaminase

Bcen_4253

Reut_B5565

integrase/recombinase

Bcen_5161

Reut_B5594

 

 

 


 

 






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Table S19. Key gene clusters shared by chromosome I of Bordetella bronchiseptica RB50 (extant representative of ancestral chromosome I) and by chromosome II of all sequenced Burkholderia strains (Burkholderia cenocepacia AU1054 used as an example) and chromosome II of all sequenced Ralstonia strains (Ralstonia eutropha JMP134 used as an example). These gene clusters are presumed to have moved from the ancestral chromosome I to the plasmid-derived chromosome II prior to the divergence of the Burkholderia and Ralstonia clades.

 

 

Product

Gene ID

 

B. bronchiseptica

B. cenocepacia

R. eutropha

putative multidrug-efflux system protein

BB0436

Bcen_3015

Reut_B4334

HlyD family secretion protein

BB0437

Bcen_3014

Reut_B4335

LysR family regulatory protein

BB0438

Bcen_3012

Reut_B4337

 

conserved hypothetical protein

BB1129

Bcen_4707

Reut_B3904

probable outer membrane protein

BB1130

Bcen_4708

Reut_B3905

 

CioA cytochrome oxidase subunit I

BB1238

Bcen_5383

Reut_B4101

CioB cytochrome oxidase subunit II

BB1239

Bcen_5382

Reut_B4100

 

GabD succinate-semialdehyde dehydrogenase [NADP+]

BB1806

Bcen_3004

Reut_B5660

GoaG 4-aminobutyrate aminotransferase

BB1807

Bcen_3006

Reut_B5663

 

MetR transcriptional regulatory protein

BB2078

Bcen_3080

Reut_B4244

MetE 5-methyltetrahydropteroyltriglutamate homocysteine methyltransferase

BB2079

Bcen_3081

Reut_B4245

 

probable acyl-CoA dehydrogenase

BB2630

Bcen_3404

Reut_B4257

MmsB 3-hydroxyisobutyrate dehydrogenase

BB2632

Bcen_3407

Reut_B4259

 

MxcB iron utilization protein

BB2831

Bcen_5142

Reut_B4272

conserved hypothetical protein

BB2832

Bcen_5141

Reut_B4273

 

probable aldehyde reductase

BB2942

Bcen_5450

Reut_B5116

LysR-family transcriptional regulator

BB2944

Bcen_5454

Reut_B5117

 

GlnQ glutamine transport ATP-binding protein

BB2974

Bcen_4282

Reut_B3697

GlnP glutamine transport system permease protein

BB2975

Bcen_4283

Reut_B3698

GlnH glutamine-binding periplasmic protein precursor

BB2976

Bcen_4284

Reut_B3699

conserved hypothetical protein

BB2977

Bcen_4281

Reut_B3696

 

putative ABC-transporter ATP-binding protein

BB3366

Bcen_3195

Reut_B4811

putative binding-protein-dependent transport protein

BB3367

Bcen_3196

Reut_B4810

 

AccB carboxyltransferase subunit of acetyl-CoA carboxylase

BB4948

Bcen_3128

Reut_B4463

AccA biotin carboxylase subunit of acetyl-CoA carboxylase

BB4949

Bcen_3130

Reut_B4460

 

 

 







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Table S20. Key gene clusters shared by chromosome I of Bordetella bronchiseptica RB50 (extant representative of ancestral chromosome I) and by chromosome II of all sequenced Burkholderia strains (Burkholderia cenocepacia AU1054 used as an example), but not shared by chromosome II of Ralstonia strains (Ralstonia eutropha JMP134 used as an example). These gene clusters are presumed to have moved from the ancestral chromosome I to the plasmid-derived chromosome II in the Burkholderia lineage after its divergence from the Ralstonia clade.

 

Product

Gene ID

 

B. bronchiseptica

B. cenocepacia

HpaE 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase

BB0736

Bcen_4133

HpaD homoprotocatechuate 2,3-dioxygenase

BB0737

Bcen_4132

 

LeuB 3-isopropylmalate dehydrogenase

BB1014

Bcen_4415

LeuD 3-isopropylmalate dehydratase small subunit

BB1015

Bcen_4416

LeuC 3-isopropylmalate dehydratase large subunit

BB1016

Bcen_4418

 

FabI enoyl-[acyl-carrier-protein] reductase [NADH]

BB1383

Bcen_3497

AckA acetate kinase

BB1384

Bcen_3495

phosphate acetyl/butaryl transferase

BB1385

Bcen_3494

 

putative iron-sulfur protein

BB1906

Bcen_4489

XseB exodeoxyribonuclease VII small subunit

BB1910

Bcen_4488

probable geranyltranstransferase

BB1911

Bcen_4487

Dxs 1-deoxy-D-xylulose 5-phosphate synthase

BB1912

Bcen_4486

conserved hypothetical protein

BB1913

Bcen_4485

 

LeuC 3-isopropylmalate dehydratase large subunit

BB2130

Bcen_4418

LeuD 3-isopropylmalate dehydratase small subunit

BB2131

Bcen_4416

LeuB 3-isopropylmalate dehydrogenase

BB2132

Bcen_4415

Asd aspartate-semialdehyde dehydrogenase

BB2133

Bcen_4414

TruA tRNA pseudouridine synthase A

BB2135

Bcen_4411

TrpF N-(5-phosphoribosyl)anthranilate isomerase

BB2139

Bcen_4410

 

putative GntR-family transcriptional regulator

BB2428

Bcen_3850

putative GNAT-family acetyltransferase

BB2429

Bcen_3849

 

FolC bifunctional folylpolyglutamate synthase/dihydrofolate synthase

BB2597

Bcen_4405

PurF amidophosphoribosyltransferase

BB2600

Bcen_4402

 

RpoD RNA polymerase sigma factor 70

BB3161

Bcen_4480

DnaG primase

BB3162

Bcen_4481

RpsU 30S ribosomal protein S21

BB3163

Bcen_4482

 

putative carboxymethylenebutenolidase

BB3237

Bcen_4491

PolA DNA polymerase I

BB3239

Bcen_4493

putative exported protein

BB3240

Bcen_4494

 

GltA citrate synthase

BB3677

Bcen_4428

SdhB succinate dehydrogenase iron-sulfur protein

BB3679

Bcen_4430

SdhA succinate dehydrogenase flavoprotein subunit

BB3680

Bcen_4431

SdhD succinate dehydrogenase membrane anchor protein

BB3681

Bcen_4432

SdhC succinate dehydrogenase cytochrome B subunit

BB3682

Bcen_4433

GntR-family transcriptional regulator

BB3683

Bcen_4434

Mdh malate dehydrogenase

BB3684

Bcen_4435

PrpB methylisocitrate lyase

BB3685

Bcen_5344

PrpC 2-methylcitrate synthase

BB3686

Bcen_5345

AcnA aconitate hydratase

BB3687

Bcen_5346

conserved hypothetical protein

BB3688

Bcen_5347

 

AccD acetyl-coenzyme A carboxylase carboxyl transferase subunit beta

BB3772

Bcen_4406

TrpA tryptophan synthase alpha chain

BB3773

Bcen_4407

TrpB tryptophan synthase beta chain

BB3774

Bcen_4409

 

BhuS putative hemin transport protein

BB4656

Bcen_4430

BhuT putative hemin binding protein

BB4657

Bcen_4429

BhuU putative hemin permease

BB4658

Bcen_4428

BhuV putative ATP-binding component of hemin transport system

BB4659

Bcen_4427

 

 







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Table S21. Key gene clusters shared by chromosome I of Bordetella bronchiseptica RB50 (extant representative of ancestral chromosome I) and by chromosome II of Ralstonia strains (Ralstonia eutropha JMP134 used as an example), but not shared by chromosome II of sequenced Burkholderia strains (Burkholderia cenocepacia AU1054 used as an example). These gene clusters are presumed to have moved from the ancestral chromosome I to the plasmid-derived chromosome II in the Ralstonia lineage after its divergence from the Burkholderia clade.

 

Product

Gene ID

 

B. bronchiseptica

R.eutropha

peptidoglycan binding protein

BB0019

Reut_B4942

two-component response regulator

BB0020

Reut_B4943

 

conserved hypothetical protein

BB0764

Reut_B3511

putative thiolase

BB0765

Reut_B3512

 

putative exported protein

BB1095

Reut_B5438

LysR-family transcriptional regulator

BB1096

Reut_B5436

probable acyl-CoA dehydrogenase

BB1098

Reut_B5437

putative exported protein

BB1099

Reut_B5438

 

conserved hypothetical protein

BB1217

Reut_B5243

enoyl-CoA dehydratase

BB1218

Reut_B5245

LysR-family transcriptional regulator

BB1219

Reut_B5246

 

conserved hypothetical protein

BB1272

Reut_B3559

putative exported protein

BB1273

Reut_B3558

 

CyoA ubiquinol oxidase polypeptide II

BB1283

Reut_B4579

CyoB ubiquinol oxidase polypeptide I

BB1284

Reut_B4578

CyoC cytochrome O ubiquinol oxidase

BB1285

Reut_B4577

 

cytochrome ubiquinol oxidase subunit IV

BB1307

Reut_B4893

cytochrome ubiquinol oxidase subunit III

BB1308

Reut_B4892

cytochrome ubiquinol oxidase subunit I

BB1309

Reut_B4891

putative ubiquinol oxidase subunit II

BB1310

Reut_B4890

putative membrane transport protein

BB1311

Reut_B4889

 

putative membrane protein

BB1825

Reut_B5408

Type II secretion system protein

BB1826

Reut_B5409

Type II secretion system protein

BB1828

Reut_B5411

putative membrane protein

BB1829

Reut_B5412

putative lipoprotein

BB1831

Reut_B5414

putative exported protein

BB1832

Reut_B5415

transcriptional regulator

BB1898

Reut_B5518

putative ABC transport permease

BB1900

Reut_B5524

 

conserved hypothetical protein

BB2262

Reut_B3511

putative thiolase

BB2263

Reut_B3512

 

FliA RNA polymerase sigma factor for flagellar operon

BB2540

Reut_B5619

FlhB flagellar transcriptional activator

BB2541

Reut_B5604

FlhC flagellar transcriptional activator

BB2542

Reut_B5605

MotA chemotaxis protein

BB2543

Reut_B5606

MotB chemotaxis protein

BB2544

Reut_B5607

CheA chemotaxis protein

BB2546

Reut_B5608

CheW chemotaxis protein

BB2547

Reut_B5609

CheR chemotaxis protein methyltransferase

BB2549

Reut_B5610

Protein-glutamate methylesterase

BB2550

Reut_B5612

CheY chemotaxis protein

BB2551

Reut_B5613

CheZ chemotaxis protein

BB2552

Reut_B5614

FlhB flagellar biosynthetic protein

BB2553

Reut_B5615

FlhF flagellar biosynthesis protein

BB2555

Reut_B5617

FlgA flagella basal body P-ring formation protein

BB2558

Reut_B5624

FlgB flagellar basal-body rod protein

BB2559

Reut_B5625

FlgC flagellar basal-body rod protein

BB2560

Reut_B5626

FlgD basal-body rod modification protein

BB2561

Reut_B5627

FlgE flagellar hook protein

BB2562

Reut_B5628

FlgF flagellar basal-body rod protein

BB2563

Reut_B5629

FlgG flagellar basal-body rod protein

BB2564

Reut_B5630

FlgH flagellar L-ring protein precursor

BB2565

Reut_B5631

FlgI flagellar P-ring protein precursor

BB2566

Reut_B5632

FlgJ peptidoglycan hydrolase

BB2567

Reut_B5633

FlgK flagellar hook-associated protein 1

BB2568

Reut_B5634

 

FliR flagellar biosynthetic protein

BB2576

Reut_B5879

FliO flagellar protein

BB2579

Reut_B5882

FliN flagellar motor switch protein

BB2580

Reut_B5883

FliM flagellar motor switch protein

BB2581

Reut_B5884

FliL flagellar protein

BB2582

Reut_B5885

 

FliJ flagellar protein FliJ

BB2584

Reut_B5101

FliH flagellar assembly protein FliH

BB2586

Reut_B5099

FliG flagellar motor switch protein FliG

BB2587

Reut_B5098

FliF flagellar M-ring protein

BB2588

Reut_B5097

FliE flagellar hook-basal body complex protein FliE

BB2589

Reut_B5096

putative flagellar protein

BB2591

Reut_B5095

FliS flagellar protein FliS

BB2594

Reut_B5092

FlaG putative flagellar protein

BB2596

Reut_B5090

 

ATP-binding component of ABC transporter protein

BB2758

Reut_B3782

TetR-family transcriptional regulator

BB2760

Reut_B3781

NapE component of of periplasmic nitrate reductase system

BB2798

Reut_B4761

NapA periplasmic nitrate reductase precursor

BB2800

Reut_B4763

NapB diheme cytochrome C precursor

BB2801

Reut_B4764

NapC cytochrome C-type protein

BB2802

Reut_B4765

CcmA Putative heme export protein

BB2803

Reut_B4766

CcmC Putative heme export protein

BB2805

Reut_B4768

CcmE cytochrome C-type biogenesis protein

BB2807

Reut_B4769

CcmF cytochrome C-type biogenesis protein

BB2808

Reut_B4770

CcmG cytochrome C-type biogenesis protein

BB2809

Reut_B4771

CcmH cytochrome C-type biogenesis protein

BB2810

Reut_B4772

putative exported protein

BB2885

Reut_B4879

putative exported protein

BB2886

Reut_B4878

 

pyridine nucleotide-disulfide oxidoreductase

BB3010

Reut_B4451

glutaredoxin

BB3011

Reut_B4452

 

putative membrane protein

BB3082

Reut_B4097

HlyD family secretion protein

BB3083

Reut_B4096

 

conserved hypothetical protein

BB3086

Reut_B4525

DNA polymerase III alpha chain

BB3088

Reut_B4523

 

hypothetical protein

BB3205

Reut_B5399

conserved hypothetical protein

BB3206

Reut_B5398

LysR-family transcriptional regulator

BB3207

Reut_B5397

 

putative membrane protein

BB3279

Reut_B5215

putative exported protein

BB3280

Reut_B5214

putative exported protein

BB3281

Reut_B5213

ApbE thiamine biosynthesis protein

BB3282

Reut_B5212

probable oxidoreductase

BB3283

Reut_B5211

 

putative 3-isopropylmalate dehydratase large subunit

BB4085

Reut_B4843

putative 3-isopropylmalate dehydratase small subunit

BB4086

Reut_B4842

 

conserved hypothetical protein

BB4341

Reut_B3555

conserved hypothetical protein

BB4342

Reut_B3554

conserved hypothetical protein

BB4343

Reut_B3553

 

probable dioxygenase

BB4476

Reut_B4145

putative exported protein

BB4481

Reut_B4142

 

putative exported protein

BB4540

Reut_B3795

putative exported protein

BB4541

Reut_B3796

CDP-6-deoxy-delta-3,4-glucoseen reductase

BB4641

Reut_B3765

conserved hypothetical protein

BB4642

Reut_B3764

aldehyde dehydrogenase

BB4643

Reut_B3763

conserved hypothetical protein

BB4644

Reut_B3762

putative membrane protein

BB4645

Reut_B3760

GntR-family transcription regulator

BB4647

Reut_B3766

ornithine cyclodeaminase

BB4648

Reut_B3761

putative ferredoxin

BB4649

Reut_B3757

hypothetical protein

BB4650

Reut_B3758

ferredoxin

BB4651

Reut_B3759

serine--glyoxylate aminotransferase

BB4671

Reut_B5140

GntR-family transcriptional regulator

BB4672

Reut_B5139

 

putative membrane protein

BB4816

Reut_B3665

CtaD cytochrome c oxidase polypeptide I

BB4830

Reut_B3633

putative exported protein

BB4843

Reut_B3614

 

AraC family regulatory protein

BB4904

Reut_B5332

PrfC peptide chain release factor 3

BB4916

Reut_B5334

 

 


 






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Table S22. Key gene clusters shared by chromosome I or chromosome II of Burkholderia pseudomallei 1710b (extant representative of bichromosomal background) and by chromosome III of those sequenced Burkholderia strains with a chromosome III (Burkholderia cenocepacia AU1054 used as an example). These gene clusters are presumed to have moved from the ancestral chromosome I or from chromosome II to the plasmid-derived chromosome III in the Burkholderia sublineage that evolved a chromosome III.

 

 

Product

Gene ID

 

B. pseudomallei chrI

B. pseudomallei chrII

B. cenocepacia

ExbD/TolR biopolymer transport protein

BURPS1710b_A3729

 

Bcen_5877

MotA/TolQ/ExbB proton channel

BURPS1710b_A3730

 

Bcen_5878

 

aldehyde dehydrogenase

BURPS1710b_A0279

 

Bcen_6479

porin, Gram-negative type

BURPS1710b_A0272

 

Bcen_6482

 

glycosyl transferase, family 2

 

BURPS1710b_B1538

Bcen_5508                              

GtrA-like protein

 

BURPS1710b_B1536

Bcen_5509                              

 

porin, Gram-negative type

 

BURPS1710b_B2774

Bcen_5613                              

YadA-like

 

BURPS1710b_B2793

Bcen_5619