The membrane-associated proteins FCHo and SGIP are allosteric activators of the AP2 clathrin adaptor complex.
Hollopeter G, Lange JJ, Zhang Y, Vu TN, Gu M, Ailion M, Lambie EJ, Slaughter BD, Unruh JR, Florens L, Jorgensen EM.
Elife. 2014 Oct 10;3. >>PubMed >>PDF
Two Rab2 interactors regulate dense-core vesicle maturation.
Ailion M, Hannemann M, Dalton S, Pappas A, Watanabe S, Hegermann J, Liu Q, Han HF, Gu M, Goulding MQ, Sasidharan N, Schuske K, Hullett P, Eimer S, Jorgensen EM.
Neuron. 2014 Apr 2;82(1):167-80. >>PubMed >>PDF
Improved Mos1-mediated transgenesis in C. elegans.
Frøkjær-Jensen C, Davis MW, Ailion M, Jorgensen EM.
Nat Methods. 2012 Jan 30;9(2):117-8. >>PubMed >>PDF
A phylogeny and molecular barcodes for Caenorhabditis, with numerous new species from rotting fruits.
Kiontke KC, Félix MA, Ailion M, Rockman MV, Braendle C, Pénigault JB, Fitch DH.
BMC Evol Biol. 2011 Nov 21;11:339. >>PubMed >>PDF
Parallel evolution of domesticated Caenorhabditis species targets pheromone receptor genes.
McGrath PT, Xu Y, Ailion M, Garrison JL, Butcher RA, Bargmann CI.
Nature. 2011 Aug 17;477(7364):321-5. >>PubMed >>PDF
A novel sperm-delivered toxin causes late-stage embryo lethality and transmission ratio distortion in C. elegans.
Seidel HS, Ailion M, Li J, van Oudenaarden A, Rockman MV, Kruglyak L.
PLoS Biol. 2011 Jul;9(7):e1001115. Epub 2011 Jul 26. >>PubMed >>PDF
The Caenorhabditis elegans GARP complex contains the conserved Vps51 subunit and is required to maintain lysosomal morphology.
Luo L, Hannemann M, Koenig S, Hegermann J, Ailion M, Cho MK, Sasidharan N, Zweckstetter M, Rensing SA, Eimer S.
Mol Biol Cell. 2011 Jul 15;22(14):2564-78. Epub 2011 May 25. >>PubMed >>PDF
Neuron-specific proteotoxicity of mutant ataxin-3 in C. elegans: rescue by the DAF-16 and HSF-1 pathways.
Teixeira-Castro A, Ailion M, Jalles A, Brignull HR, Vilaça JL, Dias N, Rodrigues P, Oliveira JF, Neves-Carvalho A, Morimoto RI, Maciel P.
Hum Mol Genet. 2011 Aug 1;20(15):2996-3009. Epub 2011 May 5. >>PubMed >>PDF
Genetics of extracellular matrix remodeling during organ growth using the Caenorhabditis elegans pharynx model.
Jafari G, Burghoorn J, Kawano T, Mathew M, Mörck C, Axäng C, Ailion M, Thomas JH, Culotti JG, Swoboda P, Pilon M.
Genetics. 2010 Nov;186(3):969-82. Epub 2010 Aug 30. >>PubMed >>PDF
C. elegans anaplastic lymphoma kinase ortholog SCD-2 controls dauer formation by modulating TGF-beta signaling.
Ammonium-acetate is sensed by gustatory and olfactory neurons in Caenorhabditis elegans.
Trio’s Rho-specific GEF domain is the missing Galpha q effector in C. elegans.
Williams SL, Lutz S, Charlie NK, Vettel C, Ailion M, Coco C, Tesmer JJ, Jorgensen EM, Wieland T, Miller KG.
Genes Dev. 2007 Nov 1;21(21):2731-46. Epub 2007 Oct 17. >>PubMed >>PDF
Genetic analysis of dauer formation in Caenorhabditis briggsae.
Inoue T, Ailion M, Poon S, Kim HK, Thomas JH, Sternberg PW.
Genetics. 2007 Oct;177(2):809-18. Epub 2007 Jul 29. >>PubMed >>PDF
UNC-31 (CAPS) is required for dense-core vesicle but not synaptic vesicle exocytosis in Caenorhabditis elegans.
Speese S, Petrie M, Schuske K, Ailion M, Ann K, Iwasaki K, Jorgensen EM, Martin TF.
J Neurosci. 2007 Jun 6;27(23):6150-62. >>PubMed >>PDF
Functional genomics and biochemical characterization of the C. elegans orthologue of the Machado-Joseph disease protein ataxin-3.
Rodrigues AJ, Coppola G, Santos C, Costa Mdo C, Ailion M, Sequeiros J, Geschwind DH, Maciel P.
FASEB J. 2007 Apr;21(4):1126-36. Epub 2007 Jan 18. >>PubMed >>PDF
NCR-1 and NCR-2, the C. elegans homologs of the human Niemann-Pick type C1 disease protein, function upstream of DAF-9 in the dauer formation pathways.
Isolation and characterization of high-temperature-induced Dauer formation mutants in Caenorhabditis elegans.