How long should one wait following a dose of enoxaparin for thromboprophylaxis to initiate neuraxial blockade?

Attempt at epidural or subarachnoid blockade should be delayed 10-12 hours following a dose of enoxaparin for thromboprophylaxis2, 7, 10.

REFERENCES

2. Horlocker-TT, Heit-JA. Low molecular weight heparin: biochemistry, pharmacology, perioperative prophylaxis regimens, and guidelines for reginoal anesthestic management [review]. Anesth Analg 1997;85:874-85.

7. Hynson-J-M, Katz-J-A, Ulrich Bueff-H. Epidural hematoma associated with enoxaparin [case report]. Anesth Analg 1996; 82:1072-5.

10. Vandermeulen-EP, Aken HV, Vermylen-J. Anticoagulants and Spinal-Epidural Anesthesia [Review]. Anesth Analg 1994;79:1165-77.

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