Griffin-R-P. Reynolds-F.
Extradural anaesthesia for caesarean section: a double-blind
comparison of 0.5% ropivacaine with 0.5% bupivacaine.
Br-J-Anaesth. 1995 May. 74(5). P 512-6.
Seventy-three parturients for elective Caesarean section
were
allocated randomly to receive extradural block with 20 ml of
either 0.5% ropivacaine or 0.5% bupivacaine. If the
block did not reach T6 within 30 min, another 5 ml of solution
was given. If needed, a further 5 ml was given 45 min after the
main dose. The mean total dose of bupivacaine was 23.1 ml (n =
35) and of ropivacaine 23.7 ml (n = 37). There was no
significant difference between the groups in the profile of
sensory block produced. There was no significant difference in
the time of onset, or intensity of motor block between the
groups but the duration of motor block was significantly
shorter in the ropivacaine group. There was no
significant difference in neonatal outcome, as assessed by
Apgar score, umbilical cord blood-gas tensions at delivery or
the neurological and adaptive capacity score 2 and 24 h after
delivery.