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Research Centers:
Spinal Drug Delivery Research Group
Seattle Children's Hospital
The Spinal Drug Delivery Research Group studies the mechanisms controlling drug distribution in CSF and spinal cord following epidural, intrathecal and systemic administration. Our long term goal is to improve selective spinal drug delivery by identifying the factors controlling drug distribution from the site of administration to the spinal cord target site. Issues of interest include barrier properties of the spinal meninges, drug metabolizing capability of the arachnoid mater, role of p-glycoprotein in the blood-brain-barrier, physico-chemical properties of drug molecules governing their spinal distribution, role of CSF motion in drug distribution, among others.
No website link is available for this group.
Spinal Drug Delivery Research Group
c/o Sean H. Flack, MB ChB, FCA
Seattle Children's Hospital
W-9824 - Anesthesia Administration
4800 Sand Point Way NE
Seattle, WA 98105
Principal Investigator: Christopher M. Bernards, MD
Faculty Investigator: Sean H. Flack, MB ChB, FCA
phone: 206-987-2518
email: sean.flack@seattlechildrens.org