D.C. Turk, Ph.D., J. Robinson, M.D., Ph.D.
Fibromyalgia syndrome (FMS) is a prevalent, chronic musculoskeletal pain disorder. Despite extensive research, the etiology and pathophysiologic mechanisms of FMS are not well understood, and no treatment has been shown to be universally effective. In this project, we propose that FMS is a complex disorder involving multiple factors, both physical and psychosocial-behavioral. In our previous research, we have demonstrated that FMS patients are heterogeneous in the psychosocial-behavioral axis and can be classified into three distinct subgroups on a basis of their psychosocial-adaptation to symptoms. In this project, we will extend our previous research and attempt to match treatments to patients' psychosocial-behavioral characteristics. Specifically, we will test the efficacy of uniquely tailored treatments for each psychosocial subgroup. Three groups of FMS patients will be treated with one of three treatment protocols with a standard physical therapy and varying psychological treatments. A total of 312 FMS patients will undergo a six half-day interdisciplinary treatment sessions consisting of physical therapy and psychological treatments. All protocols include a standardized physical therapy but include either cognitive-behavioral treatment outcome study, interpersonal skill training, or supportive counseling. In addition, to the treatment outcome study, various symptoms of FMS will be assessed prospectively in the patient natural habitats to better understand covariations of FMS symptoms. The repeated daily monitoring using the ratings compared to retrospective reports. Overall, the results of these studies should establish the benefit of matching treatments to subject characteristics, and enhance our understanding of the roles of cognitive-affective-behavioral adaptation of FMS patients.