Anesthesiology & Pain Medicine >> Research >> Labs >> Tian Lab
Photo of Rong Tian, MD, PhD
Rong Tian, MD, PhD

Tian Laboratory
Rong Tian, MD, PhD

  • Director, Mitochondria and Metabolism Center
  • Co-director, NMR center
  • Professor, Anesthesiology and Pain Medicine, Bioengineering
  • Adjunct Professor, Biochemistry

Research

  • Energy metabolism in cardiovascular diseases
  • Mitochondrial dysfunction and metabolic signaling
  • NMR spectroscopy and Imaging-guided spectroscopy

Selected Publications

  • Karamanlidis G, Nascimben L, Couper GS, Shekar PS, Tian R. Defective DNA replication impairs mitochondrial biogenesis In human failing hearts. Circ Res. 2010.
  • Yan J, Young ME, Cui L, Lopaschuk GD, Liao R, Tian R. Increased glucose uptake and oxidation in mouse hearts prevents high fatty acid oxidation but causes cardiac dysfunction in diet-induced obesity. Circulation 2009; 119:2818-2828.
  • Luptak I, Shen M, He H, Hirshman MF, Musi N, Goodyear LJ, Yan J, Wakimoto H, Morita H, Arad M , Seidman CE, Seidman JG, Ingwall JS ,Balschi JA, and Tian R. Aberrant activation of AMP-activated protein kinase remodels metabolic network in favor of cardiac glycogen storage. J Clin Invest. 2007; 117(5):1432-9.
  • Zou L, Shen M, Arad M, He H, Lofgren B, Ingwall JS, Seidman CE, Seidman JG, Tian R. N488I mutation of the γ2-subunit results in bi-directional changes in AMPK activity. Circ Res 2005 97(4):323-328.
  • Liao R, Jain M, Cui L, D'Agostino J, Aiello F, Ngoy S, Mortensen RM, Tian R. Cardiac-specific overexpression of GLUT1 prevents the development of heart failure due to pressure-overload in mouse. Circulation 2002, 106, 2125-2131.