Converting to/from Betrixaban

CONVERTING TO/FROM AGENTS FOR
VTE PROPHYLAXIS
UW MEDICINE RECOMMENDATION
From  heparin SQ, dalteparin SQ, enoxaparin SQ, fondaparinux SQ, apixaban, dabigatran or rivaroxaban (all dosed for VTE prophylaxis) to  betrixaban Stop the other agent, and give betrixaban at the time that the next dose of the other agent would have been given                                                     
From betrixaban to heparin SQ, dalteparin SQ, enoxaparin SQ, fondaparinux SQ , apixaban, dabigatran or rivaroxaban (all dosed for VTE prophylaxis) Stop betrixaban, and give the other agent at the time that the next dose of betrixaban would have been given
CONVERTING TO/FROM AGENTS FOR
FULL ANTICOAGULATION

[assuming that  full anticoagulation can be discontinued during period of VTE prophylaxis with betrixaban]
UW MEDICINE RECOMMENDATION
From warfarin to betrixaban Stop warfarin and start betrixaban when INR < lower limit of therapeutic range
From betrixaban to warfarin Start warfarin and stop betrixaban when INR > lower limit of therapeutic range
From heparin IV to betrixaban Stop heparin and start betrixaban when PTT < lower limit of therapeutic range
From betrixaban to heparin IV Start heparin IV and stop betrixaban when PTT > lower limit of therapeutic range
From heparin SQ, dalteparin SQ,  enoxaparin SQ, fondaparinux SQ , apixaban, dabigatran, edoxaban or rivaroxaban (all dosed for full anticoagulation) to betrixaban Stop the other agent, and give betrixaban at the time that the next dose of the other agent would have been given 
From betrixaban to heparin SQ, dalteparin SQ,  enoxaparin SQ, fondaparinux SQ , apixaban, dabigatran, edoxaban or rivaroxaban (all dosed for full anticoagulation) Stop betrixaban, and give the other agent at the time that the next dose of betrixaban would have been given