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Vol. III, No. 7~ EINet News Briefs ~ May 23, 2000


****A free service of the APEC Emerging Infections Network*****

The EINet listserv was created to foster discussion, networking, and collaboration in the area of emerging infectious diseases (EID's) among academicians, scientists, and policy makers in the Asia–Pacific region. We strongly encourage you to share their perspectives and experiences, as your participation directly contributes to the richness of the "electronic discussions" that occur. To respond to the listserv, use the reply function.


In this edition:

  1. Infectious disease information from ProMED and other sources
  2. Updates from previous bulletins
  3. Notices
  4. How to join the EINet listserv


1. OVERVIEW OF INFECTIOUS–DISEASE INFORMATION FROM PROMED  
Below is a bi–weekly summary of Asia–Pacific EID issues based on postings to the ProMED Electronic Network and other sources. ProMED is the prototype for a communications system that monitors emerging infectious diseases globally, an initiative of the Federation of American Scientists (FAS), and co–sponsored by WHO.

ASIA

POTENTIAL AIDS CRISIS
According to the National Intelligence Council, infectious disease–related deaths may increase substantially in Asia and the Pacific, as HIV/AIDS continues to spread throughout southeast Asia. It has been speculated that the number of HIV–related deaths in this region could surpass Africa's within the next 10 years.

Contributing factors to the potential AIDS crisis include the dependence on traditional medicine, the vulnerability of the private health care system, and the economic situation in Asia.
[AP WIRE 5/3/00]

REEMERGING DISEASES THREAT
Asian health ministers have pledged to collaborate in the battle against reemerging infectious diseases like tuberculosis and malaria, as well as AIDS. Non–governmental groups estimate that AIDS cases could reach as high as 150,000, as prostitution and intravenous drug use continue to rise. In Thailand, one people are HIV positive; this is the highest level of HIV infection recorded in the region. The potential of other disease outbreaks is also strong, due to increased international travel and the ensuing flow of migrants.

Health ministers aim to address rapid contingency plans for disease outbreaks, support for comprehensive disease surveillance, and an accurate monitoring system. Many Asian countries currently participate in a cross–border agreement to alert neighboring countries about malaria outbreaks.
[STRAITS TIME 5/1/00]


OCEANIA

AUSTRALIA–LEGIONNAIRES' DISEASE TRACED TO AQUARIUM
The Public Health Division of the Government of Victoria has recorded 91 cases of legionnaires' disease, including 19 hospitalizations and 2 fatalities. The outbreak has been traced to the Melbourne Aquarium, visited by a majority of the cases between April 11㪱, 2000. Laboratory tests confirmed the presence of Legionella bacteria in the cooling towers of the Aquarium.

This is the largest outbreak of legionellosis in Australia since 1987, during which time 10 fatalities were reported.
[XINHUA NEWS AGENCY 5/12/00; WHO/EMC DISEASE OUTBREAKS 5/4/00]

AUSTRALIA–CREUTZFELDT–JAKOB DISEASE
Ten patients were exposed to Cruetzfeldt–Jakob Disease (CJD) during April 1㪴, 2000 after inadequate sterilization of tools used during neurosurgery. A dementia patient who may be infected with CJD has since been treated at Royal Melbourne Hospital (RMH).

CJD is an incurable disease; it is believed to be caused by abnormal infectious proteins called prions, which are highly resistant to destruction by usual heating methods. CJD cannot be diagnosed until symptoms are exhibited.
[NEWS.COM.AU 5/5/00]

NEW ZEALAND–STAPHYLOCOCCUS AUREUS
The number of methicillin–resistant Staphylococcus aureus (MRSA) cases recorded at Capital Coast Health has increased 50% in the past few months. Over 100 cases have been reported since June 1999. Four wards in Wellington Hospital––each with a reported increase of cases––have been isolated to prevent further spread of the infection. Patients and relatives have been instructed to wear gloves for any formal patient contact.

MRSA resists almost all antibiotics. Infection can be life threatening to immunocompromised patients.
[ONE NEWS 5/15/00]


AMERICAS


USA (CHICAGO)–EOSINOPHILIC MENINGITIS
Five cases of eosinophilic meningitis were reported earlier this month, after vacationing in Jamaica over spring break. Of the 22 who took the trip, 7 complained of unremitting headaches, stiff necks, and alternating numbness and tingling sensations in their limbs within a week upon their return. The disease was probably contracted from a food–borne parasitic worm called the rat lungworm, a native of Southeast Asia, but spreading globally.

A non–contagious form of meningitis, eosinophilic meningitis is transmitted through the ingestion of raw or insufficiently cooked snails, slugs, or land planarians–intermediate or transport hosts harboring infective larvae. Symptoms usually include severe headaches, neck and back stiffness, and paresthesias. Illness can last between a few days to several months.
[INTERNET TRIBUNE 5/4/00]

USA–IMMIGRATION POLICIES TO ELIMINATE TUBERCULOSIS
According to the Institute of Medicine (IOM), 40% of new tuberculosis (TB) cases in the U.S. are imported from countries like Asia and Africa, where over half the population is infected. In an effort to eliminate TB, the IOM committee on the Elimination of Tuberculosis in the United States has urged the government to modify immigration policies and increase funding for TB research. A report issued by the Committee recommends that changes to the current U.S. immigration policy are tailored to strengthening the identification of TB cases and treatment of active cases, and improving screening for latent infections among high–risk groups. Specifically, immigrants from high–prevalence countries should be required to receive a tuberculin skin test prior to entry into the country, and documents granting permanent residency should be withheld until immigrants receive the necessary screening or treatment upon arrival.

The Committee also called upon the U.S. to increase financial and technical support to nations where the incidence of the disease is high, to help bolster research activities, as well as to identify and treat latent infections. Currently, the National Institute of Health (NIH) and the U.S. Centers for Disease Control and Prevention (CDC) contribute $60 to $80 million dollars to TB research.
[REUTERS MEDICAL NEWS 5/5/00]


OTHER

'HUMAN' INFLUENZA B IN SEALS
According to a study published in Science, seals may be the natural reservoir for influenza B, a virus strain that was once thought to be unique to humans. The virus, which was first discovered in an 8–month old harbor seal last spring, closely resembled the strain that circulated among humans about 5 years ago. The strain had also remained stable since 1995; this was a significant finding in particular, because influenza strains that circulate among humans mutate and undergo antigenic drift.

Blood samples of 971 seals from the Netherlands' Seal Rehabilitation and Research Centre revealed that 2% of the seals that arrived at the Institute after 1995 had influenza B antibodies, compared to none who arrived prior to then. It is believed that the seals were infected with the strain during an outbreak five years ago, and that the virus has since spread among themselves.
[GLOBE AND MAIL 5/13/00]

SOUTHERN RUSSIA–HEMORRHAGIC FEVER
An outbreak of hemorrhagic fever has surfaced in Stavropol. To date, 10 people have fallen ill, and 2 women have died. Stavropol health officials believe the outbreak of the fever–which is spread by ticks–is a result of the unusually warm weather, thereby leading to an increased rate of ticks multiplying.

According to the ITAR–Tass news agency, there were 3 fatalities from the disease recorded in Stavropol last year; and no cases had reported previous to then. Tick control efforts are currently underway.
[ITAR–TASS NEWS AGENCY 5/12/00]


2. UPDATES FROM PREVIOUS BULLETINS

JAPAN–FOOT AND MOUTH DISEASE
There is fear that foot and mouth disease (FMD) has spread to one of Japan's main cattle regions, after two new suspected cases of FMD were reported on the northern island of Hokkaido last week. To date, 705 cows at a farm in Hokkaido have been destroyed. The suspected outbreak was reported shortly after two prefectures on the southern island of Kyushu declared elimination of the disease, following an outbreak in March.

There is speculation that the disease may have surfaced in Japan through straw or hay imported from Taiwan, China, or South or North Korea.
[STRAITS TIME 5/13/00; ProMED 5/13/00]

ROTASHIELD INCREASES RISK OF INTUSSUSCEPTION IN INFANTS
The U.S. Centers for Disease Control and Prevention (CDC) has confirmed an increased risk of intussusception among infants who receive the rotavirus vaccine, Rotashield (Wyeth–Ayerst). The conclusion supported the CDC's recommendation to withdraw Rotashield earlier this year, after 15 infants developed intussusception upon vaccination. It is believed that the total number of cases was underreported.

The mortality rate from intussusception is less than 0.5% in the U.S.; however, in developing countries, the rate is as high as 20%. The need for a rotavirus vaccine in less developed countries is substantial, particularly, because medical care is not adequate.
[REUTERS MEDICAL NEWS 5/12/00]


3. NOTICES

NEW LINK ON APEC EINet
"Reports From the Rim" is a newly established link that will be comprised of reports about infectious diseases in the Pacific Rim. Submissions by APEC EINet members are strongly encouraged. For more information, please contact nwc@u.washington.edu.

The Enterovirus Epidemic of Taiwan, 1998�, a report by Dr. Ping–Ing Lee, MD, PhD (Department of Pediatrics, National Taiwan University Hospital), can now be accessed through this link.

ASIA–PACIFIC CONGRESS OF MEDICAL VIROLOGY
The 5th Asia–Pacific Congress of Medical Virology will be held in Denpasar–Bali, Indonesia during June 26㪴, 2000. To register for the Congress, please contact Dr. Amin at amin0207@rad.net.id or apcmv@rad.net.id ; a paper must also be submitted for the Late Breaker's Session.

AIDS DISCUSSION GROUP IN HONG KONG
An e–mail group has been established to discuss issues concerning the AIDS campaign in Hong Kong, information about the community planning process, and other relevant news. Organizations and individuals are also welcome to post information to the e–mail group. To subscribe, please contact iAIDS@hongkong.com, or visit http://come.to/cppforum/


4. JOIN THE E–LIST AND RECEIVE EINet NEWS BRIEFS REGULARLY
The APEC EINet listserv was established to enhance collaboration among academicians and public health professionals in the area of emerging infections surveillance and control. Subscribers are encouraged to share their material with colleagues in the Asia–Pacific Rim. To subscribe (or unsubscribe), please contact nwc@u.washington.edu. Further information about the APEC Emerging Infections Network is available at http://www.apec.org/infectious.

Revised:
April 21, 1999

Contact us at apecein@u.washington.edu
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