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Vol. III, No. 9 ~ EINet News Briefs ~ July 5, 2000


****A free service of the APEC Emerging Infections Network*****

The EINet listserv was created to foster discussion, networking, and collaboration in the area of emerging infectious diseases (EID's) among academicians, scientists, and policy makers in the Asia–Pacific region. We strongly encourage you to share their perspectives and experiences, as your participation directly contributes to the richness of the "electronic discussions" that occur. To respond to the listserv, use the reply function.


In this edition:

  1. Infectious disease information from ProMED and other sources
  2. Updates from previous bulletins
  3. Notices
  4. How to join the EINet listserv


1. OVERVIEW OF INFECTIOUS–DISEASE INFORMATION FROM PROMED  
Below is a bi–weekly summary of Asia–Pacific EID issues based on postings to the ProMED Electronic Network and other sources. ProMED is the prototype for a communications system that monitors emerging infectious diseases globally, an initiative of the Federation of American Scientists (FAS), and co–sponsored by WHO.

ASIA

INDONESIA––DENGUE FEVER
To date, dengue fever has claimed at least 11 lives and caused nearly 280 hospitalizations in Kalimantan province. Approximately 130 people have also been hospitalized in neighboring Balikpapan.

Over the past 5 months, 8 fatalities have been recorded in the provincial capital of Samrinda; while, in Jakarta, the number of people dying from dengue fever has fallen to 22 (n=646).
[JAKARTA POST 6/2/00]

MALAYSIA––NIPAH VIRUS ALERT
Over 1,700 pigs have been slaughtered after the Nipah virus was discovered at a pig farm in Gopeng, located in the northern state of Perak. Health officials fear that the pig–borne virus is reemerging. Random tests conducted on May 23 and 27 at another pig farm in Gopeng revealed 6 pigs to be positive (n=30). The government is currently awaiting the results of blood samples collected randomly from 188 farms throughout the state; according to Perak Veterinary Services, all pigs in the state will be culled if the blood samples are found positive.

There is speculation that Nipah virus has returned amid smuggling activities of piglets from previously affected farms, and inadequate practices of animal husbandry. Since last October, a nationwide operation to conduct random examinations of pig farms has been enforced. The Malaysian Cabinet has ordered the relevant ministries to contain the situation, particularly with closer surveillance into pig farming in Perak.
[THE STRAITS TIMES 6/22/00; YAHOO! ASIA NEWS 6/20/00; THE STAR ONLINE 6/17/00]

JAPAN––CONTAMINATED MILK
Over 6,000 people in 8 prefectures fell ill after drinking contaminated milk produced from the country's biggest dairy product maker, Snow Brand Milk Product. The source of the outbreak is believed to be a milk solid found inside a valve in the plant production line (Osaka). The contaminant was described as the size of a 10 yen coin.

Presumably, bacteria inside the valve were not detected during on–the–spot inspection as a result of the the company's failure to report on the facilities it used to recycle leftover products (i.e. temporary pipes, spare tanks).
[www.yomiuri.co.jp/newse/0703cr05.htm]

JAPAN––E.COLI
An outbreak of E.coli 0157 infection has been reported in Fuino–machi (Kenagawa Prefecture), a hospital and home for the elderly. Between June 14㪩, a total of 21 cases from the hospital or home reported diarrhea; isolation of E.coli 0157 bacteria and Vero toxin have been confirmed in 6 patients by the public health center of the local government. The number of recognized and suspected patients has since risen to 52. The source of contamination has not yet been identified.
[NEWS MEDIA, JAPAN 6/22/00]


AMERICAS


USA & CANADA––POTENTIAL E.COLI CONTAMINATION
Over 200 tons of ground beef have been voluntarily recalled by the world's largest meat packing company, IBF Inc. after E.coli contaminated samples were found by the U.S. Department of Agriculture and Costco Wholesale Corp. The recall involved lean ground beef produced in May at packing plants in Illinois (USA), and Alberta (Canada).
[REUTERS 6/23/00]


OTHER

RUSSIA––CHILDREN CONTRACT SMALLPOX
Eight children have contracted a mild form of smallpox after playing with glass ampoules of smallpox vaccine dumped outside a public health clinic in Vladivostok, a far eastern port.

The smallpox vaccine is made from vaccinia virus, a member of the family of viruses to which smallpox belongs; however, it is different from the virus that causes smallpox. As a result, the children are not at risk to develop full–blown smallpox. The negligence of the local epidemiologic center not to incinerate the ampoules before discarding them has been raised.
[REUTERS 6/20/00; THE TIMES 6/20/00]

WHO––ANTIMICROBIAL USE IN FOOD ANIMALS
The World Health Organization (WHO) has issued a report, "Global Principles for the Containment of Antimicrobial Resistance due to Antimicrobial Use in Animals Intended for Food", to address the overuse and misuse of antimicrobial agents.

Report recommendations include:

  • Termination or rapid phasing–out of the use of antimicrobials for growth promotion if they are also used for treatment of humans in the absence of a public health safety evaluation
  • Creation of national systems to monitor antimicrobial usage in food animals
  • Monitoring of resistance to identify emerging health problems and timely corrective actions to protect human health
  • Guidelines for veterinarians to reduce overuse and misuse of antimicrobials in food animals

Salmonella, and other enterococci infections, were noted bacteria that have become resistant to all available antimicrobials.
[REUTERS MEDICAL NEWS 6/14/00; WHO PRESS RELEASE WHO/43 6/13/00]

WHO––MISUSE OF ANTIBIOTICS
According the World Health Organization (WHO), the increasing misuse of antibiotics may lead to the emergence of new "superbugs" that resist all drugs. The alarming rate by which drug resistance continues to spread has been attributed to overuse of antibiotics in wealthy nations, incomplete and under–use of medications in poor nations, and the widespread practice of feeding livestock low levels of antibiotics to promote growth.

The WHO has advised health professionals to reduce the number of antibiotic prescriptions. Other recommendations include a major international effort to bring more anti–infection medications to poor nations, and to avoid use of antibiotics for human treatments as growth promoters for animals.
[WASHINGTON POST 6/13/00; BBC NEWS 6/13/00; FOX NEWS COM 6/13/00; WHO REPORT ON INFECTIOUS DISEASES 2000 6/12/00 WHO/CDS/2000.2]

LIVES CLAIMED BY DISEASE EXCEED THAT OF WAR
A report published by the International Federation of Red Cross and Red Crescent Societies cited a deterioration of public health services, evidenced by 13 million deaths from preventable diseases last year. An estimated 150 million people have died from AIDS, tuberculosis (TB), and malaria alone since 1945, compared to 23 million in wars. In 1999, 160 times more people died of AIDS, malaria, respiratory diseases, and diarrhea, than the total number killed in natural disasters (including the massive earthquake in Turkey and the floods in Venezuela).

Funding for health has plummeted since 1991. In poor countries, public health expenditure on health averages 1% of the gross domestic product (GDP), compared to 6% in richer countries. The report concluded that changing people's attitudes and behavior will save more lives than expenditure on expensive institutions and equipment.
[DESERET NEWS 6/28/00]


2. UPDATES FROM PREVIOUS BULLETINS

**CORRECTION** NIPAH VIRUS IDENTIFIED AS A NEW GENUS OF VIRUSES
Dr. KB Chua of the University of Malaya Medical Center, and researchers at the U.S. Centers for Disease Control (CDC) and Australia's Commonwealth Scientific and Industrial Research Organization, have identified Nipah Virus as the etiologic agent of an outbreak of severe encephalitis in Malaysia in 1998. The virus was first isolated by Dr. KB Chua.

Genetic analysis confirmed a close relationship between Nipah Virus and the recently discovered Hendra Virus, which sickened horses and killed 2 people in Australia in 1994. Tests revealed a strong reaction between Nipah Virus and antiserum for Hendra Virus. The Nipah Virus, apparently spread by coughing pigs, killed over 100 people in Malaysia and Singapore during 1998 and 1999.
[SCIENCE 2000 (288): 1432㪻 REUTERS 5/26/00]
*Special thanks to Prof. Lam Sai Kit (Dept. of Medical Microbiology, University of Malaya) for sharing this information with EINet*

USA (NEW YORK)––LOCALLY ACQUIRED MALARIA
The New York State Health Department has confirmed two epidemiologically linked cases of Plasmodium vivax reported in Suffolk county last summer. Both cases involved 11 year–old boys who attended summer camp during the same week in August; symptoms appeared within 4 days of each other. No other malaria cases at the camp or in the surrounding areas were reported.

Health officials believe that the infections were caused by a bite of a locally infected Anopheles mosquito.
[MMWR 2000; 49: 495𤯢]


3. NOTICES

PHILLIPINES––ELECTRONIC FORUM LAUNCHED
PinoyRH–an electronic forum about sexual and reproductive health in the Phillipines– is a service that disseminates information about reproductive health issues (i.e. maternal mortality and family planning). PinoyRH also encourages subscribers to share information. PinoyRH messages may be written in Filipino or English. To join, please contact: pinoy–subscribe@egroups.com
[SEA AIDS 6/21/00]


4. JOIN THE E–LIST AND RECEIVE EINet NEWS BRIEFS REGULARLY
The APEC EINet listserv was established to enhance collaboration among academicians and public health professionals in the area of emerging infections surveillance and control. Subscribers are encouraged to share their material with colleagues in the Asia–Pacific Rim. To subscribe (or unsubscribe), please contact nwc@u.washington.edu. Further information about the APEC Emerging Infections Network is available at http://www.apec.org/infectious.

Revised:
April 21, 1999

Contact us at apecein@u.washington.edu
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