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Vol. II, No. 15 ~ EINet News Briefs~ July 27, 1999


****A free service of the APEC Emerging Infections Network*****

The EINet listserv was created to foster discussion, networking, and collaboration in the area of emerging infectious diseases (EID's) among academicians, scientists, and policy makers in the Asia–Pacific region. We strongly encourage you to share their perspectives and experiences, as your participation directly contributes to the richness of the "electronic discussions" that occur. To respond to the listserv, use the reply function.


In this edition:

  1. Overview of infectious–disease information from PRO–MED and other sources
  2. Updates from previous bulletins
  3. Notices
  4. How to add colleagues to the EINet listserv





1. OVERVIEW OF INFECTIOUS–DISEASE INFORMATION FROM PROMED   Here is our regular summary of relevant Asia–Pacific EID issues based on postings to the ProMED Electronic Network, which is a prototype for a communications system to monitor emerging infectious diseases globally as an initiative of the Federation of American Scientists (FAS), co–sponsored by WHO.


ASIA

CHINA – TOXIC ALGAE ALERT
A red tide alert is in effect in northern and southern China following an alert in the Bohai Sea area in eastern China last week. The red tide appears to be spreading, and currently covers 680 square kilometres. Shrimp and fish farmers have been advised to stop pumping ocean water into their ponds. Seafood contaminated by the fast–breeding, oxygen–depleting algae, is unsafe to eat. Worsening pollution has led to an increase in the size and duration of red tides in recent years, and 22 red tides were reported along China's coasts in 1998. [ProMed, July 13, July 20,1999]

CHINESE TAIPEI – CHOLERA O139
Taiwan's second indigenous case of cholera was reported on July 08, 1999. The patient, a 73 year old man, became ill after a dinner of "hot steamboat" with 17 relatives on June 27. The toxigenic O139 strain of Vibrio cholerae was cultured from the patient.
[ProMed, July 1, 1999]
Note: The O139 strain of Vibrio cholerae was first isolated in India in 1996.

KOREA – VIBRIO FOOD POISONING
The Korea Food and drug Administration (KFDA) has issued a warning against food poisoning following detection of vibrio bacteria in the West and South Seas. Vibrio parahaemolyticus was discovered in 11 coastal areas. Vibrio cholerae has also been found on the West Coast and the National Institute of Health expects cases of cholera to be reported. 50 workers came down with food poisoning after eating fried squid and meat soup provided at a company meal on Yongchongdo islet off Inchon.
[Korea Times, July 16, 1999]

HONG KONG – IMPORTED CASE OF RABIES
The Department of Health has confirmed a report of a suspected case of human rabies imported from the Philippines. The victim was a 22 year–old woman who gave a history of having been bitten by a dog on May 15 this year in her rural home in the Philippines, one week before coming to Hong Kong. The last local human case of rabies in Hong Kong was reported in 1981, the last imported human case was in 1988, and the last animal case was reported in 1987.
[Dr. KH Mak, Department of Health, Hong Kong, July 14, 1999]

PHILIPPINES – FILARIASIS
Local health authorities in Baikingon, Cagayan Province, have urged residents to destroy all possible breeding sites of mosquitoes. This advice follows the results of blood tests in the city which found 59 people infected with filariasis. A survey showed that filariasis–carrying mosquitoes were present in the region. [Xinhua, July 14, 1999]

VIETNAM – LETHAL MALARIA RESURGENCE
An increase in the number of malaria cases in Vietnam has health officials worried about the situation. The disease was wiped out in the northern region from 1954 to 1962, but came back with a vengeance in 1991, which saw 144 outbreaks with more than 1 million victims and 4,600 fatalities. Following the efforts of the government and local health care authorities, the disease was brought under control between 1992 and 1997. The disease, however, has made a comeback, and a total of 183 people died of malaria last year. There were 130,403 malaria patients nationwide in the first five months of this year, 6.8% less than the same period in 1998. However, the main concern is an increase in the number of malignant malaria cases, which has increased to 625, representing an increase of 51.7% over the same period in 1998. Migrant laborers and changing weather conditions have been blamed for the increase in cases.
[Xinhua, July 16, 1999]


OCEANIA

NEW ZEALAND – WHOOPING COUGH OUTBREAK
An outbreak of whooping cough is spreading in Southland as predicted by health authorities. The outbreak began last month when 16 cases were reported to health officials. Southland may be the starting point of a nationwide epidemic that was predicted as a result of low immunization rates in a previous bulletin (Vol. II, No. 10).
[The Press, July 16, 1999]

NEW ZEALAND – NINTH YEAR OF MENINGITIS EPIDEMIC
New Zealand is going through the ninth year of an epidemic of meningitis, which is expected to last another five to seven years. The disease has been labeled as a public health emergency. Experts are urging the Ministry of Health to accelerate vaccine trials for serogroup B meningococcus which affects about 85% of those who contract meningitis in New Zealand. 210 cases and 6 deaths have been reported nationally this year. A higher than normal incidence of influenza could be contributing to the meningitis outbreak.
[The Press, July 21, 1999] [New Zealand Herald, July 27, 1999]


AMERICAS

CANADA – E. COLI OUTBREAK
Public health officials are investigating an outbreak of E. coli in the Mocton area. At least 13 cases have been reported in the area since the first week of June, and five have been hospitalized.
[Globe and Mail, July 15, 1999]

MEXICO – HUMAN EHRLICHIOSIS
The first human case of ehrlichiosis in Mexico was reported in Yucatan in February 1999. Ehrlichiosis is tick–borne zoonotic disease, the clinical spectrum of disease being similar to other febrile illnesses. Without adequate and timely treatment, approximately 5% of patients die. A deliberate search for cases is indicated following this report of the first human case in Mexico.
[ProMed, July 13, 1999]

USA – VIBRIO PARAHEMOLYTICUS IN OYSTERS
Consumption of oysters tainted by Vibrio parahemolyticus has sickened 368 people in Texs, Florida, Oklahoma, Georgia, Tennessee, Colorado, and California. Galveston Bay was closed to oyster harvesting on June 26.
[ProMed, July 25, 1999]

USA (TEXAS)– ST. LOUIS ENCEPHALITIS ALERT
An advisory against St. Louis encephalitis is in effect in southeast Dallas following a positive test in a chicken, indicating that mosquitoes in the area are carrying the virus. Routine insecticide spraying is being carried out, and the public have been advised to be aware of stagnant water, which is a breeding habitat for mosquitoes. [ProMed, July 10, 1999]

USA – ROTAVIRUS VACCINATION SUSPENDED
Following the development of intussusception in at least 23 children who received a new vaccine against rotavirus, the CDC and the American Academy of Pediatrics are recommending the postponement and suspension of vaccinations for rotavirus until November 1999. Parents of vaccinated children have been advised to watch for symptoms of the condition.
[CNN, July 15, 1999]

USA – LYME DISEASE FASTEST GROWING INFECTIOUS DISEASE
The incidence of Lyme disease, a tick–borne disease, is expected to increase this summer as result of larger deer tick populations than last year. This increase has been attributed to the lasting effects of El Nino. Individuals spending time outdoors are at risk of contracting the disease, which if left untreated can progress to debilitating, long–term arthritic or neurologic conditions.
[PR Newswire, July 15, 1999]


OTHER

NEW AND AFFORDABLE DRUG REDUCES MOTHER–TO–CHILD HIV TRANSMISSION Nevirapine, a new drug that costs only US$4 per treatment has been shown to reduce mother–to–child transmission of HIV more effectively than the currently used AZT. The study involved 600 HIV–infected mothers in Uganda, and involved two doses of nevirapine, one given during labor, and one given to the newborn three days after delivery. The risk of transmitting the virus to the child dropped to 13%, compared to 25㪶% without any HIV medications. The drug while being affordable may also reduce transmission of the virus through breast milk.
[CNN, July 14, 1999]

VITAMIN A REDUCES MALARIA ATTACKS
A team of researchers has studied the effect of Vitamin A supplements in reducing the number of malaria attacks in 240 children between six months and five years of age. A 30% reduction in malaria episodes was associated with Vitamin A, approaching levels of protection seen with insecticide–treated bednets and exceeding protective levels of field–tested experimental malaria vaccines. The most striking improvements were seen in children between 12 and 36 months of age, who normally have the highest sickness rate. The supplements did not have any impact on the rate of anemia and did not prevent the most intense malaria attacks.
[Reuters, July 15, 1999]

NASAL SPRAY PREVENTS FLU
A nasal spray has proved to be effective in protecting healthy adults against the flu virus, and the painless vaccine is expected to reach the market within two years. The findings were published in the Journal of the American Medical Association. The spray, called FluMist, would offer an alternative to the standard flu shot. [Associated Press, July 15, 1999]


2. UPDATES FROM PREVIOUS BULLETINS

USA (MARYLAND)– LEGIONELLOSIS
A third person has succumbed to Legionnaire's disease at Harford Memorial Hospital in Maryland, bringing to five the total number of confirmed cases. Additional cases are expected as the incubation period for the disease is 2㪢 days, and the water system was flushed on July 02. The bacteria has also been isolated from a nursing one day after the death of a former resident who was sent to Harford Memorial Hospital, suggesting that the exposure was not confined to the hospital.
[ProMed, July 13, July 20, 1999]


3. NOTICES 

APEC ISTWG MEETINGS – SEATTLE, AUGUST 15㪬
The APEC Working Group on Industrial Science and Technology will meet in Seattle, August 15㪬. Organizers have planned a seminar for Monday, August 16, on emerging infections in the region, and a side meeting of delegates to consider progress under the APEC Initiative on Emerging Infections (adopted 1997) will be held on Tuesday, August 17. Colleagues in Health and Science in APEC economies are advised to contact their ISTWG delegation heads for further information, or to contact Laura Schubert (lschub@u.washington.edu) for further information.


4. HOW TO JOIN THE EMAIL LIST and receive EINet News Briefs regularly    The APEC EINet listserv was established to enhance collaboration among academicians and public health professionals in the area of emerging infections surveillance and control. Subscribers are encouraged to share their own material with their colleagues in the Asia–Pacific Rim. To subscribe (or unsubscribe), please contact Nedra Floyd Pautler at pautler@u.washington.edu. Further information about the APEC Emerging Infections Network is available at http://www.apec.org/infectious.