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Vol. II, No. 16 ~ EINet News Briefs ~

August 10, 1999


****A free service of the APEC Emerging Infections Network*****

The EINet listserv was created to foster discussion, networking, and collaboration in the area of emerging infectious diseases (EID's) among academicians, scientists, and policy makers in the Asia–Pacific region. We strongly encourage you to share their perspectives and experiences, as your participation directly contributes to the richness of the "electronic discussions" that occur. To respond to the listserv, use the reply function.

In this edition:

1. APEC ISTWG MEETINGS – SEATTLE, AUGUST 15㪬
2. Overview of infectious disease information from ProMED and other sources
3. Updates from previous bulletins
4. How to add colleagues to the EINet listserv



1. APEC ISTWG MEETINGS – SEATTLE, AUGUST 15㪬
The APEC Working Group on Industrial Science and Technology will meet in Seattle, August 15㪬. Organizers have planned a seminar for Monday, August 16, on emerging infections in the region. A side meeting of delegates to discuss progress under the APEC Initiative on Emerging Infections (adopted 1997) will take place on Tuesday, August 17. Colleagues in Health and Science in APEC economies are advised to contact their ISTWG delegation heads or to contact Laura Schubert (lschub@u.washington.edu), for further information.



2. OVERVIEW OF INFECTIOUS–DISEASE INFORMATION FROM PROMED   Here is our regular summary of relevant Asia–Pacific EID issues based on postings to the ProMED Electronic Network, which is a prototype for a communications system to monitor emerging infectious diseases globally as an initiative of the Federation of American Scientists (FAS), co–sponsored by WHO.


ASIA

CHINA – 70% HIV INFECTION RATE AMONG INTRAVENOUS DRUG USERS
According to the China Daily newspaper, eight different strains of HIV/AIDS have been identified in China, placing them at the head of the field in the number of HIV/AIDS viruses isolated. It was also found that 70% of intravenous drug users were HIV positive. 47.5% of samples were subtype B, and over 34% were subtype C, which orginated from drug users in India. 9.6% were subtype E, which came from southeast Asia. [SEA–AIDS, August 06, 1999]

HONG KONG – REPORT ON INFLUENZA A H9N2
A report on the two cases of influenza A H9N2 suggests that this type of avian flu virus causes relatively mild illness in humans and poses no imminent threat to public health. While the possibility of human–to–human transmission remains open, the main mode of transmission was from birds to humans. There was no evidence for reassortment with influenza virus genes. Enhanced surveillance for human and poultry infections will continue, and the public has been issued an advisory against the disease. 70% of poultry and four more people were found to have been exposed to the new strain of virus. 2% of 100 poultry workers, compared 0.6% of 500 people from the general population tested positive for antibodies against the virus. Centralized slaughter of poultry is being actively considered by health officials, though no concrete plans have been produced so far.
[Dr. Mak Kwok Hang, Hong Kong Department of Health, August 03, 1999] [South China Morning Post, August 04, 1999]

HONG KONG – 400–FOLD RISE IN WATER BACTERIA
Bacteria levels in water pumped into Hong Kong have incrased almost 400–fold in the past six months, according to a survey done by a lobby group.
E. coli had increased 390 times, while other bacteria levels had risen 239 times in the same area over a six month period. Run–off from pig farms and industries have contributed to the problem. Tests showed that every 100 millimeters of water had up to 1.25 million E. coli organisms at Wei Zhou, up from 3,200 in December.
[South China Morning Post, August 04, 1999]

JAPAN (TOKYO) – SERRATIA BACTERIA IN HOSPITAL WARD
Seven inpatients at a hospital in Tokyo's Sumida Ward were infected with serratia bacteria, three of whom died last week. 14 inpatients at Sumida Central Hospital reported suffering fevers and other symptoms early last week. The three women who died were in their 70s, and hence weakened immune systems are suspected to be the predisposing factors. Nevertheless, hospital staff have been advised to take preventive measures, and to examine the possibility of further infections.
[Japan Times, August 03, 1999]

JAPAN – Q FEVER
An outbreak of Q Fever is currently going on in Japan, and the Japanese Respiratory Society will soon be establishing guidelines to effectively diagnose and treat the illness. The disease, caused by Coxiella burnetii, spreads from animals to humans by inhalation, and causes pneumonia and hepatic disorder. 237 patients at 18 hospitals in Miyagi Prefecture were studied over a two–year period, and 3.4% were found to have the bacterium. Half of the patients had contact with animals before they noticed symptoms. This is the first time a widespread outbreak of Q Fever has been reported in the nation.
[ProMED, August 10, 1999]

PHILIPPINES – DENGUE REPORTING INCREASED
Increased awareness of dengue has been cited as a reason for an increase in the number of cases reported so far this year. The provincial health office in Pangasinan recorded 63 cases last month, the highest this year, and a total of 125 cases since January. 742 cases of dengue were reported in Nueva Ecija since January accounting for 22.08% of the national incidence.
[ProMED, July 31, 1999]

KOREA/PHILLIPINES – EPIDEMIC ALERT DUE TO FLOODING
Health officials in Korea and the Phillipines are trying to prevent the outbreak of water–borne diseases like dysentery, and stomach and skin diseases and measles as a result of flooding in these countries. Overcrowding in evacuation centers and low medical supplies pose a threat in the Phillipines, while in Korea, lack of potable water and exposure to contaminated water are already reported to have caused skin diseases and dysentery. Health officials in Korea have also issued a nationwide warning against Japanese Encephalitis and advised parents to vaccinate their 3㪧 year old children against the disease. The warning comes after more than half of the mosquitoes tested on the southern island of Cheju late last month were found to be carrying the virus causing Japanese Encephalitis.
[Korea Herald, August 05 and 07, 1999] [Phillipine Inquirer, August 05, 1999]


OCEANIA

AUSTRALIA (VICTORIA) – INCREASE IN LEGIONNAIRE'S DISEASE
Legionnaire's disease is a rapidly increasing disease in Australia, particularly in Victoria. The number of cases have doubled since 1997, and so far this year, a 40% increase has been reported. A third of these cases have been in Victoria. Better diagnosis and increased use of air conditioning have been cited as reasons for the increase in Victoria. Since the public are notified only when more than one case is linked to a definite site, official figures may not reflect the true incidence of the disease.
[ProMed, Aug. 01, 1999]

AUSTRALIA (TASMAINIA) – INFLUENZA–LIKE ILLNESS
An illness that resembles influenza has killed several Tasmanians in the past three weeks. A doctor at Royal Hobart Hospital has confirmed the deaths and believes the illness to be a viral respiratory infection that was not influenza. The patients who died were high–risk patients who had already had lung disease before they contracted the infection. Many of the hospital's staff have also been ill with the infection. Major influenza epidemics are currently occurring elsewhere in Australia and New Zealand.
[ProMED, August 05, 1999]


AMERICAS

USA (MASSACHUSETTS)– SHIGELLOSIS OUTBREAK
An outbreak of shigellosis in Hampden County that has affected 24 people has public health officials on the alert. Most of the cases have involved person–to–person contact within families or small groups. Day care centers, camps, and food vendors have been urged to take precautions to prevent the spread of the disease. [ProMed, Aug. 01, 1999]

USA (OHIO) – E. COLI OUTBREAK
An outbreak of E. coli 0157:H7 has affected at least 25 people in four counties. Investigators from the Centers for Disease Control and Prevention (CDC) are currently trying to identify the source of outbreak. It is more likely that more than one source of contamination was involved in the outbreak due to the lack of common circumstances among the cases. DNA fingerprinting using the pulsed field gel electrophoresis is currently underway. So far, two samples have been matched. Three cases in Kentucky and one in Indiana have been reported, and officials are investigating the possibility of a link to the local clusters in Ohio. No deaths have been reported.
[ProMED, August 08, 1999]

USA (CONNECTICUT) – HEMOLYTIC UREMIC SYNDROME
Infection with E. coli is suspected in ten children who became ill after swimming in a lake in East Haddam. Three children developed hemolytic uremic syndrome.
[ProMED, August 07, 1999]

USA – DRUG RESISTANT STREPTOCOCCUS PNEUMONIAE
The Centers for Disease Control (CDC), using data collected from a population–based surveillance system in 1997 has found that the prevalence of drug–resistance Streptococcus pnuemoniae has increased from 14% in 1993㫶 to 25%. Regional variation in resistance was noted along with a wide range of resistance among individual hospitals.
[ProMED, August 08, 1999]


OTHER

RUSSIA – DRUG RESISTANT TUBERCULOSIS
The percentage of primary multi–drug resistant tuberculosis cases in Russia has increased from 3.8% to 9.4% between 1996 and 1998. This study was part of an international collaboration with the WHO, CDC, and others.
[ProMED, August 08, 1999]


3. UPDATES FROM PREVIOUS BULLETINS

AUSTRALIA – ENTEROVIRUS 71
The epidemic of hand, foot, and mouth disease (HFM) associated with enterovirus type 71 in Perth appears to be declining. No new cases of acute flaccid paralysis or enteroviral meningitis have been reported recently, and far fewer cases of HFM have been reported in the past two weeks.
[ProMED, July 30, 1999]

MALAYSIA – NIPAH VIRUS
A slaughterhouse worker who marked pig carcasses is the latest victim to succumb to the Nipah virus. Officials found this finding troubling because the risk of infection is low for those at the end of the slaughter process compared to those who handle live pigs. Scientists are still trying to answer questions about the virus with regard to its predilection to the brain, immune response, and selectivity of people affected.
[ProMED, July 31, 1999]

NEW ZEALAND – FLU EPIDEMIC
The influenza epidemic in New Zealand has affected more than 10% of adults, and workplaces are bearing the brunt of the illness. This year's epidemic has hit mainly working–age adults. While the Sydney A virus is the main culprit, a B strain could also be circulating as well. Workers in almost every industry have been affected, and nursing staff are particularly hard hit. People's attitude towards the disease and vaccinations have been cited as main reasons fro the epidemic making New Zealand's influenza–prevention program inadequate.
[ProMED, August 05, 1999]

USA – E. COLI O111
Barrels of ice used by participants of the drill team on the University of North Texas campus have been identified as the source of contamination in the outbreak of E. coli O111 in June. While the original source of the organism is unknown, investigators believe that one or more campers could have contributed to contamination of the ice, especially since they used their hands to scoop out the ice from barrels. [ProMed, July 30, 1999]

USA – SALMONELLA CONATMINATION FROM MEXICO
Isolation of salmonella bacteria from a tanker load of juice from Mexico, has led to a ban on imports of Mexican orange juice. Blended juice from Mexico has been identified as the source of salmonellosis that struck more than 200 people throughout the West, including 32 in Arizona. The juice was sent back to Mexico and the Mexican producer must pass inspection for Salmonella five times before the juice will be allowed into the United States again. [ProMed, July 30, 1999]

USA (MULTISTATE) – CYCLOSPORIASIS
The source of contamination in an outbreak of cyclosporiasis that sickened 94 people has been narrowed down to a fresh fruit platter, though there is no evidence to single out which fruit carried the bacteria. Berries may be the source, as some raspberries and blackberries might have come from Guatemala.
[ProMED, August 01, 1999]

INFLUENZA ACTIVITY
Alaska, the Yukon Territory, New Zealand, and Australia are continuing to experience outbreaks of influenza. The Sydney strain of influenza A (H3N2) has been identified in Alaska and the Yukon Territory, while influenza A and B have been isolated in New Zealand and Australia. An outbreak of influenza at San Antonio's Lackland Air Force Base in Texas, USA, has affected at least 165 members. Most of the members are from Puerto Rico and are studying English at the Defense language Institute in San Antonio.
[ProMED, August 1ס, 1999]


4. HOW TO JOIN THE EMAIL LIST and receive EINet News Briefs regularly    The APEC EINet listserv was established to enhance collaboration among academicians and public health professionals in the area of emerging infections surveillance and control. Subscribers are encouraged to share their own material with their colleagues in the Asia–Pacific Rim. To subscribe (or unsubscribe), please contact Laura Schubert at lschub@u.washington.edu. Further information about the APEC Emerging Infections Network is available at http://www.apec.org/infectious.