Cooper, Khatib et al, Nature, 466, 756-60. (2010)
Examples of blind structure prediction problems in which players were successfully able to improve structures. Native structures are shown in blue, starting puzzles in red, and top scoring Foldit predictions in green.
(a) The red starting puzzle had a register shift and the top scoring green Foldit prediction correctly flips and slides the beta strand.
(b) On the same structure as above, Foldit players correctly buried an exposed Isoleucine in the loop on the bottom right by remodeling the loop backbone.