Graduate Program in Neurobiology & Behavior

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N&B Focus Groups

• Behavioral Neuroscience
• Cell and Molecular Neuroscience
• Computational Neuroscience
• Developmental Neuroscience
• Disorders of the Nervous System
• Excitable Membranes and Synaptic Transmission
• Invertebrate Neurobiology
• Motor Systems and Sensorimotor Integration
• Neuroendocrinology
• Neurotransmitters, Modulators, Transporters and Receptors
• Sensory Systems

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• Development
• Diversity Matters
• Graduate Training
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• Steering

Jihong Bai

jbai@fhcrc.org  -  206-685-0111
Assistant Member, Division of Basic Sciences, Fred Hutchinson Cancer Research Center; Affiliated Assistant Professor, Department of Biochemistry

Lab Website    

Our research goal is to understand how synapses develop into functional circuits. Synaptic connections undergo constant fine-tuning to support information delivery and storage in the brain. Regulation of these connections occur through altering the strength of existing synapses or through synapse assembly and disassembly. We utilize a combination of genetic, biochemical, imaging, and electrophysiological techniques to study the following aspects of synaptic biology, including 1) synaptic protein dynamics and its role in supporting neuronal activity and developmental cues; 2) synaptic vesicle endocytosis and its coupling to exocytosis; and 3) the genetic program for synapse remodeling.