Neonatal ICU Issues

Neonatal ICU Issues: Case 2

B.R. is a term female infant from an unexpected pregnancy. She has Down syndrome (Trisomy 21) and also has a complex cardiac lesion that will require at least two major surgical procedures during early infancy for her to have a chance to survive beyond childhood. B.R.'s parents, ages 44 and 45, have three other children, all in college. They have considerable ambivalence as to what to do: continue to pursue potentially beneficial though burdensome and costly treatments, or forego such treatments in favor of a more conservative approach.

What are the issues involved?

Neonatal ICU Issues: Case 1

M.S. is a married 35-year-old pregnant childless woman who has lost four previous pregnancies between 16 and 23 weeks gestation. She currently has reached 23 weeks and 3 days of gestation, her fetus is seemingly healthy, and has an estimated weight of 550 grams (+/-1.2 lbs). She has ruptured her bag of waters and is now having labor that seems unstoppable with tocolytics. Delivery seems inevitable.

What are the management options and who decides what form of care should be instituted following delivery?

 

Neonatal ICU Issues

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Authors:

CASE STUDIES

M.S. is a married 35-year-old pregnant childless woman who has lost four previous pregnancies between 16 and 23 weeks gestation. She currently has reached 23 weeks and 3 days of gestation, her fetus is seemingly healthy, and has an estimated weight of 550 grams (+/-1.2 lbs). She has ruptured her bag of waters and is now having labor that seems unstoppable with tocolytics. Delivery seems inevitable.

What are the management options and who decides what form of care should be instituted following delivery?

 

Case Discussion

This gestational age and estimated birth weight represent the "gray zone" in terms of viability vs. non-viability. Accordingly, the parents have a choice to make. They can choose a palliative care mode of treatment (with non-survival being a virtual certainty) or alternatively, assisted ventilation, pressors, antibiotics, parenteral nutrition, etc. The role of the physician is to provide continuity, regularly updated information,  Â and guide the parents through the decision-making process throughout the infant’s clinical course, whatever it may be.

This situation 40 years ago would have presented no ethical dilemma. Indeed, the 1972 Roe v. Wade Supreme Court case defined the limit of viability as 28 weeks gestation. Any form of aggressive care involving newborn infants below this gestational was thought to be medically futile. Today, however, aggressive measures at birth are sometimes initiated with a modest degree of success achieved in terms of promoting survival (nearing 50% for 23-24 week infants). Notably, survival is accompanied by a long stay in the hospital following delivery (3-4 months), enormous costs (see above), considerable suffering, and morbidity (in at least 50% of the cases there is significant handicap).

B.R. is a term female infant from an unexpected pregnancy. She has Down syndrome (Trisomy 21) and also has a complex cardiac lesion that will require at least two major surgical procedures during early infancy for her to have a chance to survive beyond childhood. B.R.'s parents, ages 44 and 45, have three other children, all in college. They have considerable ambivalence as to what to do: continue to pursue potentially beneficial though burdensome and costly treatments, or forego such treatments in favor of a more conservative approach.

What are the issues involved?

Case Discussion

That the child has Down syndrome should not be a factor in the decision-making process. Moreover, it is also not appropriate to allow financial issues to play a major role. The parents, who are the decision-makers, should be apprised of the medical facts (types of surgical interventions required, chances for success). They should also be given a good understanding of the amount of suffering the child will experience during aggressive intervention efforts. They should then come to a decision based on the child's best interests.