Professor and Chair
Office: A-204H Health Sciences Building
Assistant's Phone: 206-221-6548
| Recent Publications | Honors,
Awards, Grants | Courses | Curriculum
Dr. Wylie Burke
is Professor and Chair of the Department of Bioethics and Humanities
at the University of Washington. She is also Principal Investigator of the University of Washington Center for Genomics and Healthcare Equality, an NIH-funded Center of Excellence in Ethical, Legal, and Social Implications (ELSI) Research. Her research addresses the social, ethical and policy implications of genetic information.
Dr. Burke received a Ph.D. in Genetics and an M.D. from the University of Washington and completed a residency in Internal Medicine at the University of Washington. She was a Medical Genetics Fellow at the University of Washington from 1981 to 1982. Dr. Burke was a member of the Department of Medicine
at the University of Washington from 1983 to 2000, where she served
as Associate Director of the Internal Medicine Residency Program from
1988 to 1994 and as founding Director of the University of Washington's
Women's Health Care Center from 1994 to 1999. She was appointed Chair
of what was then known as the Department of Medical History and Ethics in October 2000. The department became Bioethics and Humanities in 2008. She is also an
Adjunct Professor of Medicine and Epidemiology and a Member
of the Fred Hutchinson Cancer Research Center. She was
a Visiting Scientist at the Centers for Disease Control and Prevention
in 1998 and an International Fellow at the National Health Service, Cambridge UK in 2006. She is a member of the Institute of Medicine and the Association of American Physicians and a past president of the American Society of Human Genetics.
- Burke W, Psaty BM. Personalized medicine in the era of genomics. JAMA 2007;298:1682-4.
- Tarini B, Burke W, Scott CR, Wilfond B. Waiving informed consent in newborn screening research: balancing social value and respect. Am J Med Genet 2008 Feb 15;148C:23-30.
- Haga S, Burke W. Pharmacogenetic testing: not as simple as it seems. Genet Med. 2008;10:391-5.
- McGuire AL, Burke W. An unwelcome side effect of direct to consumer personal genome testing: raiding the medical commons. JAMA 2008;300:2669-71. [PMC2789655]
- Hindorff LA, Burke W, Laberge AM, Rice KM, Lumley T, Leppig K, Rosendaal FR, Larson EB, Psaty BM. Motivating factors for physician ordering of factor V Leiden genetic tests. Arch Intern Med. 2009 Jan 12;169(1):68-74. [PMC2651814]
- Burke W, Culver J, Pinsky L, Hall S, Reynolds SE, Yasui Y, Press N. Genetic assessment of breast cancer risk in primary care practice. Am J Med Genet 2009; Part A 149A;349-56. [PMC2688688]
- Laberge A-M. Hindorff LA, Psaty BM, Burke W. Use of Factor V Leiden genetic testing in practice and impact on management. Genet Med. 2009 Oct;11:750-6.
- Culver J, Bowen DJ, Reynolds SE, Pinsky LE, Press N, Burke W. Breast cancer risk communication: Assessment of primary care physicians by standardized patients. Genet Med. 2009;11:735-41.
- Laberge AM, Watts C, Porter K, Burke W. Assessing the Potential Success of Cystic Fibrosis Carrier Screening: Lessons Learned from Tay-Sachs Disease and beta-Thalassemia. Public Health Genom, 2010;13:310-9. Epub 2009 Oct 26
- Fullerton SM, Yu JH, Crouch J, Fryer-Edwards K, Burke W. Population description and its role in the interpretation of genetic association. Hum Genet. 2010;127:563-72.
- Trinidad SB, Fullerton SM, Bares JM, Jarvik GP, Larson EB, Burke W. Genomic research and wide data sharing: views of prospective participants. Genet Med. 2010;12:486-95.
- Veenstra DL, Roth JA, Garrison LP Jr, Ramsey SD, Burke W. A formal risk-benefit framework for genomic tests: Facilitating the appropriate translation of genomics into clinical practice. Genet Med 2010;12:686-93.
- Meacham MC, Starks H, Burke W, Edwards K. Researcher perspectives on disclosure of incidental findings in genetic research. J Empir Res Hum Res Ethics 2010; 5: 31–41.
- Ludman EJ, Fullerton SM, Spangler L, Trinidad SB, Fujii MM, Jarvik GP, Larson EB, Burke W. Glad You Asked: participants' opinions of re-consent for dbGap data submission. J Empir Res Hum Res Ethics. 2010; 5:9-16.
- Burke W, Laberge A-M, Press N. Debating clinical utility. Public Health Genom. 2010;13:215-23. Epub 2010 Apr 15.
- Beskow LM, Burke W. Offering individual genetic research results: context matters. Sci Transl Med. 2010 Jun 30;2(38):38cm20.
- Burke W, Burton H, Hall AE, Karmali M, Khoury MJ, Knoppers B, Meslin EM, Stanley F, Wright CF, Zimmern RL; Ickworth Group. Extending the reach of public health genomics: what should be the agenda for public health in an era of genome-based and “personalized” medicine? Genet Med. 2010 Dec;12(12):785-91.
- Trinidad SB, Fullerton SM, Ludman EJ, Jarvik GP, Larson EB, Burke W. Research practice and participant preferences: the growing gulf. Science. 2011 Jan 21;331(6015):287-8.
Awards, Honors and Grants Received
Elected to the Institute of Medicine (2007)
President, American Society
of Human Genetics (2007)
NHS International Fellow, Public Health Genetics Unit, Cambridge
Principal Investigator, Center for
Genomics and Healthcare Equality - a Center of Excellence in ELSI
Research funded by the National Human Genome Research Institute
Named one of Seattle's Best Doctors
by Seattle Magazine (September 2006)
Named a "Local Legend", (Celebrating
America's Local Women Physicians), Washington State