Lisa K. Lafleur, et al. Lab on a Chip, 2016, 16, 3777-3787. The researchers demonstrate a prototype of MAD NAAT, the first fully integrated, sample-to-result diagnostic platform for performing nucleic acid amplification texts that require no permanent instrument or manual sample processing.
Microvascular Injury and Perfusion Changes Induced by Ultrasound and Microbubbles in a Machine-Perfused Pig Liver
Christina P. Keravnou, Ine De Cock, Ine Lentacker, Maria-Louisa Izamis, Michalakis A. Averkiou. Ultrasound in Medicine & Biology, 2016 Nov;42(11):2676-2686. The researchers combined ex vivo machine-perfused pig livers with an image-guided therapy system to investigate applications of ultrasound-driven microbubbles to enhance drug delivery, and demonstrate a versatile, physiologically relevant platform for pre-clinical research.
Barrett J. Nehilla, John J. Hill, Selvi Srinivasan, Yen-Chi Chen, Thomas H. Schulte, Patrick S. Stayton, and James J. Lai. Analytical Chemistry. 2016, 88 (21), 10404–10410. The researchers present a stimuli-responsive binary reagent system, and how it illustrates the potential advantages of nanoscale reagents in molecule and cell isolations for both research and clinical applications.
Mechanical Stress Conditioning and Electrical Stimulation Promote Contractility and Force Maturation of Induced Pluripotent Stem Cell-Derived Human Cardiac Tissue
Jia-Ling Ruan, Nathaniel L. Tulloch, Maria V. Razumova, Mark Saiget, Veronica Muskheli, Lil Pabon, Hans Reinecke, Michael Regnier, Charles E. Murry. Circulation. 2016; 134:1557-1567. The researchers demonstrate how electric pacing and mechanical stimulation promote maturation of the structural, mechanical and force generation properties of human-induced pluriopotent stem cell-derived cardiac tissues.
Y. Cheng, R. C. Yumul, S. H. Pun, Angewandte Chemie International Edition. 2016, 55, 12013. Researchers demonstrate a synthetic polymer, VIPER, designed to mimic viral mechanisms of delivery, and that may have potential as a gene delivery platform for cancer therapy and other macromolecule therapeutics.
The latest update on UW Bioengineering's advances in research, education, translation and outreach, and the recent achievements of our students and faculty.
Bioengineering Outreach and Honors team adapts toys for children with disabilities at holiday toy hack event
At the TCAT Hack for Access: Holiday Toy Event on Sunday December 11, volunteers from UW and the Seattle community adapted toys for children with disabilities – just in time for the holidays!
Image: A 3D-printed four-valve switch (left) is shown connected to a 3D-printed cell culture chamber (right). [...]
Image: BioE Ph.D. student Molly Mollica talks with Seattle's King 5 TV about the importance [...]
A drive to engineer solutions to global health problems compelled recent Yager lab Ph.D. graduate Joshua Buser to pursue bioengineering. He aims to bring diagnostic testing to low-resource settings – and increase access to affordable health care closer to home.