Research Interests
• Microfluidic devices for chemical and biochemical measurement
• Development of point-of-care diagnostic instruments
• Microfabrication technologies for microfluidics
• Development of microfluidic-specific methods of analysis of biological samples
• Biophysics of self-organizing systems, particularly lipid systems
Contact Information
Department of Bioengineering
University of Washington
Box 355061
William H. Foege Building, Room N530J
Phone: 206-543-6126
Fax: 206-543-6124
E-mail: yagerp@u.washington.edu
Web Site: http://faculty.washington.edu/yagerp
For chair related business:
William H. Foege Building, Room N107E
Phone: 206-685-2002
Fax: 206-685-3300
E-mail: bioechr@u.washington.edu
Teaching Activities
- BIOEN 599: Bioengineering Applications of Microfabrication
This course is aimed at preparing graduate students to use 2- and 3-dimensional structures with features between 1mm and 0.1um in their research with biomaterials complex liquids. It has a 3-credit lecture section and an accompanying optical laboratory in which PDMS devices are made for use in the students' research.
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BIOEN 573: Biosensors: Principles and Practice
A graduate level course (open to qualified undergraduates) designed to give students an in-depth acquaintance with the growing and complex field of biosensors.
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BIOEN 578: Biomembranes
A graduate course (open to qualified undergraduates), the focus of which is develping an understanding of the molecular principles that underlie the self-assembly of surfactants into natural and model biomembranes - in particular, on the relationship between the chemical structure of lipid molecules and the three dimensional aggregates that they form in water.
- More information is available at the following address: http://faculty.washington.edu/yagerp/syllabi.html.
Honors, Awards, and Society Activities
- 1975: Elected Associate Member of Sigma Xi, Princeton Chapter
- 1979: Molecular Biology Training Grant, Institute of Molecular Biology, Eugene, Oregon
- 1980: Awarded a Resident Research Associateship by the National Research Council
- 1983: Naval Research Laboratory Research Publication Award
- 1984-85: Government Employees' Incentive Awards
- 1985: Chemistry Division Superior Technical Publication Award
- 1985: Nominated for National Science Foundation Waterman Award
- 1988: Nominated by UW for Packard Fellowship
- 1992-current: Who's Who in Science and Engineering
- 1999: Selected as a member of the College of Fellows, American Institute for Medical and Biological Engineering (AIMBE)
Selected Publications
- Biotechnology at low Reynolds numbers, Brody, J.P., Yager, P., Goldstein, R.E., and Austin, R.H., Biophysical Journal. 71 (6), 3430-3441, (1996).
- Zero-order interfacial enzymatic degradation of phospholipid tubules, Carlson, P.A., Gelb, M.H., and Yager, P., Biophysical Journal, 73(1), 230-239 (1997).
- Formation of high axial ratio microstructures from natural and synthetic sphingolipids, Goldstein, A.S., Lukyanov, A.N., Carlson, P., Yager, P., and Gelb, M.H., Chem. Phys. Lipids, 88, 21-36 (1997).
- Comparative structural characterization of naturally and synthetically-spun fibers of Bombyx mori fibroin, Trabbic, K.A. and Yager, P., Macromolecules, 31(2), 462-471 (1998).
- Microfluidic diffusion-based separation and detection, Weigl, B.H. and Yager, P., Science, 283(5400), 346-347 (1999)
- Quantitative analysis of molecular interaction in a microfluidic channel: the T-sensor, Kamholz, A.E., Weigl, B.H., Finlayson, B.A. and Yager, P., Analytical Chemistry, 71(23), 5340-5347 (1999)
- Generation of natural pH gradients in microfluidic channels for use in isoelectric focusing, Macounová, K., Cabrera, C.R., Holl, M.R. and Yager, P., Analytical Chemistry, 72(16), 3745-3751 (2000).
- Theoretical analysis of molecular diffusion in pressure-driven laminar flow in microfluidic channels, Kamholz, A.E. and Yager, P., Biophysical Journal, 80, 155-160 (2001)
- Formation of natural pH gradients in a microfluidic device under flow conditions: Model and experimental validation, Cabrera, C.R., Finlayson, B.A., and Yager, P., Analytical Chemistry, 73(3), 658-666 (2001)
- Continuous concentration of bacteria in a microfluidic flow cell using electrokinetic techniques, Cabrera, C.R. and Yager, P., Electrophoresis, 22(2), 355-362 (2001)
- A rapid diffusion immunoassay in a T-Sensor, Hatch, A., Kamholz, A.E., Hawkins, K.R., Munson, M.S., Schilling, E.A., Weigl, B.H. and Yager P., Nature Biotechnology, May, 2001
Complete CV at: http://faculty.washington.edu/yagerp/pycv.html.
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