Xiaohu Gao

Associate Professor

xgao@u.washington.edu
Phone: (206)543-6562
Office: Foege N530M

UW Bioengineering faculty Xiaohu Gao

Lab Website
How I am inventing the future of medicine
My research group is interested in nanomedicine, which is the use of engineered nanostructures for detection, analysis and treatment of human diseases such as cancer, cardiovascular diseases, infectious diseases and neurological diseases.
Research Interests
Nanomedicine/Nanotechnology
Molecular engineering
Molecular imaging
Targeted drug delivery
Research Description
The Gao research group is interested in molecular engineering and nanomedicine, using engineered nanostructures for detection, analysis and treatment of human diseases such as cancer, cardiovascular diseases, infectious diseases and neurological diseases.

Nanotechnology has recently received broad interest from biomedical researchers and may change the very foundations of disease diagnosis, treatment and prevention. From technology development side, currently we are developing semiconductor quantum dots (Qdots) for optical imaging, magnetic nanoparticles for MRI and magnetic manipulation, metallic nanoparticles for photoacoustic imaging and image-guided therapy, and polymeric and natural protein nanoparticles for drug delivery. From the application side, we are interested in molecular screening, diagnosis, prognosis, and treatment. In general, we are interested in any innovative nanotechnology that has impact on biology and medicine.

Education
PhD, Chemistry, Indiana University, Bloomington, 2004
BS, Chemistry, Nankai University, China, 1998
Postdoc Information
Postdoctoral Research Associate, Winship Cancer Institute at Emory University, 2004-2005
Awards and Honors
2013 Elected fellow of AIMBE (American Institute for Medical and Biological Engineering)
2010 Faculty innovator award, College of Engineering, University of Washington
2007 CAREER Award, National Science Foundation
UW Bioengineering Courses Taught
BIOEN 487: Bioengineering and Nanotechnology
BIOEN 599: Grad Imaging 2: Optical Bio-Imaging
Selected Publications
M.Y. Han, X.H. Gao, J. Su, and S.M. Nie, “Quantum-dot-tagged microbeads for multiplexed optical coding of biomolecules,” Nature Biotechnology 2001, 19, 631-635.

X.H. Gao, Y. Cui, R.M. Levenson, L.W.K. Chung, and S.M. Nie, “In vivo cancer targeting and imaging with semiconductor quantum dots,” Nature Biotechnology 2004, 22, 969-976.

Y.D. Jin and X.H. Gao, Plasmonic fluorescent quantum dots, Nature Nanotechnology. 2009, 4, 571-576

Y.D. Jin , C. Jia , S.W. Huang, M. O’Donnell and X.H. Gao, Multifunctional nanoparticles as coupled contrast agents, Nature Communications, 2010, 10.1038/ncomms1042.

P. Zrazhevskiy, X.H. Gao, Quantum dot imaging platform for single-cell molecular profiling, Nature Communications, doi: 10.1038/ncomms2635, 2013.

P. Zrazhevskiy, L.D. True, and X.H. Gao, Multicolor multicycle molecular profiling (M3P) with quantum dots for single-cell analysis, Nature Protocols, 8, 1852-1869, 2013

 

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