Molecular Bioengineering
Description
- Controlled release of therapeutic agents
- Targeted delivery of therapeutic agents & nucleic acids
- Better protein-binding molecules for diagnostics & therapeutics
- Nanoparticulate systems
- Molecular mechanics 7 protein folding
Core Faculty
James D. Bryers. Bacterial adhesion, biofilm formation, biomedical device-based infections, gene delivery, and bacterial vaccines.
David Castner. Biomedical surface analysis, biomolecule-surface interactions, biomaterials and nanotechnology.
Valerie Daggett. Protein folding; dynameomics/bioinformatics; extremophile proteins; protein modulators; protein design; unfolding diseases; protein complexes; single nucleotide polymorphisms.
Lara Gamble. Surface modification and characterization of model biomedical system, fundamental research towards the preparation and characterization of DNA and protein microarrays, new techniques for improved analysis of the biomolecule-surface interface.
Xiaohu Gao. Engineered nanostructures for detection; analysis and treatment of human diseases; cardiovascular diseases; infectious diseases; neurological diseases.
Cecilia M. Giachelli. Molecular and cellular approaches to promote healing, biocompatibility, tissue regeneration and biomineralization.
Allan Hoffman. Polymer synthesis of smart polymer bioconjugates and hydrogels for drug and gene delivery.
Thomas Horbett. Interests in the fundamental response of tissues to implanted polymeric biomaterials, focusing on protein and cell interactions at interfaces.
Henry C. Lai. Biological effects of electromagnetic fields; cancer treatment using artemisinin and synthetic compounds.
Matthew O'Donnell. Exploring new imaging modalities in biomedicine, including elasticity imaging, in vivo microscopy, optoacoustic arrays, optoacoustic contrast agents for molecular imaging and therapy, thermal strain imaging, and catheter based devices.
Gerald H. Pollack. Unexpectedly profound ordering of water at interfaces; role of water and light in natural processes; molecular basis of biological motion; engineering of water-based technologies for solving societal problems.
Suzie Pun. Development of polymeric drug and gene delivery vehicles. Incorporation of delivery systems with scaffolds, matrices and implant surfaces for tissue engineering applications.
Buddy Ratner. The Ratner group engineers biomaterial surfaces to control biological interactions, synthesized, characterized and observed during interaction with biological systems.
Daniel M. Ratner. Glycotechnology; modification of surfaces with glycans; carbohydrate mediated host-pathogen interactions; glycoproteomics.
Michael Regnier. Contracile protein and tissue engineering for cardiac repair following heart attack and for treatment of cardiac disease.
Joan Sanders. The Sander’s group tissue engineers of vessel substitutes, heart valves, and vascular plexus.
Patrick Stayton. Protein engineering; biomaterials; drug delivery; biomineralization.
Narendra P. Singh. DNA damage/repair; apoptosis; aging and cancer.
Wendy E. Thomas. Mechanical regulation of reversible and nonfouling biomaterial adhesives, bacterial adhesion and biofilms, platelet adhesion, and thrombosis.
Pedro Verdugo. Polymer networks; self-assembly of marine biopolymers and their role in global carbon cycling; ion-exchange properties, hydration equilibrium, and phase transition of secretory matrixes; development of biopolymer matrix-carriers for vaccine preservation.
Paul Yager. Microfluidic devices for chemical & biochemical measurement & analysis; point-of-care diagnostic instruments; global health.
Adjunct Faculty
Dayong Gao. Cryopreservation and fundamental cryobiology; bio-heat-mass transfer and thermal stress; artificial kidney; nano-technology/nano-fluid/membrane science; development of optimal technology and equipment; tissue engineering; cardiovascular and blood research
Blake Hannaford. Neural control of movement; robotics; human-machine interaction; telerobotics.






