Course title: Bioengineering 493/593 – Advanced Surface Analysis, Winter 2013 (Chemical Engineering 493/593)

Instructor: D.G. Castner (Office: MolES 225, Phone:  206-543-8094 e-mail: castner@uw.edu)

Office hours: by appointment

Lectures: Wednesday, Friday – BNS 203, 12:30-1:50pm

Reference Text (Optional): Surface Analysis: The Principal Techniques, J.C. Vickerman, Editor, 1997 (1st edition) or 2009 (2nd edition)

Website: https://www.nb.uw.edu/advsurfanal/

UW Catalog Description: Latest advances in surface analysis instrumentation and methodology, including advanced methods in Biorecognition AFM, Surface Plasmon Resonance, X-ray Photoelectron Spectroscopy, Sum Frequency Generation Spectroscopy, Time-of-flight Secondary Ion Mass spectrometry, Multivariate Analysis.

Prerequisites: Bioen 492/592 or Cheme 458/558.

Learning Objectives: By the end of this course, students should be aware of the latest experiments that can be done and information that be provided by surface analysis methods. They should also be able to analyze and discuss the results obtained from advanced surface analysis instrumentation and methods.

Student PresentationsGraduate students will each do one 20-minute critique of literature papers. The range of topics for the critiques are the same as those covered during lectures (see above). Selection of a specific critique topic must be approved in advance by the instructor. An electronic copy of slides used for the presentation must be e-mailed to the instructor before 5pm on the day of the presentation.

Midterm Exams: Two mid-term exams will be given covering the topics presented in the lectures.

Class Participation: All students are expect to be active in the discussion of material presented in lecture and participate in the question and answer sessions associated with each student presentation.

Final Paper: Instead of the final exam, each student will submit a paper (8 pages for undergraduates and 12 pages for graduates) using 1” margins, 1.5 line spacing and 12 point font on an advanced surface analysis technique.  The topic for this paper must be approved by the instructor. The advance surface analysis method discussed in the paper can’t be one the student is currently using in their research projects, but it can be one the students are considering to use in the future. Papers are to be submitted by the final exam time period for this course.

Graduate Grading: Oral Critique
Final Paper
100 points
150
Midterm Exams (50 pts each) 100
Class Participation 50
maximum possible 400 points
Undergraduate Grading: Final Paper
Midterm Exams (50 pts each)
150 points
100
Class Participation
maximum possible
50
300 points

Course Schedule:

Wed, Jan 9 High Resolution XPS
Fri, Jan 11 Biorecognition AFM
Wed, Jan 16 Optical Reflection Methods for Thin Film Characterization (Patrick Koelsch)
Fri, Jan 18 Surface Plasmon Resonance: Kinetics & Biosensing
Wed, Jan 23 Non-linear optical methods: Fundamentals & Instrumentation (Patrick Koelsch)
Fri, Jan 25 Applications of NLO Spectroscopy & Imaging (Patrick Koelsch)
Wed, Jan 30 Surface Modification Methods (Buddy Ratner)
Fri, Feb 1 XPS Imaging
Wed, Feb 6 Mid-term Exam #1
Fri, Feb 8 Student Oral Critiques
Wed, Feb 13 XPS Analysis of Supported Nanoparticles
Fri, Feb 15 XPS Analysis of Biomedical Nanoparticles
Wed, Feb 20 Multivariate Analysis: Fundamentals (Dan Graham)
Fri, Feb 22 Multivariate Analysis:  Spectral Processing (Dan Graham)
Wed, Feb 27 Multivariate Analysis:  Image Processing (Dan Graham)
Fri, Mar 1  Polyatomic ToF-SIMS
Wed, Mar 6 ToF-SIMS Depth Profiling
Fri, Mar 8 Student Oral Critiques
Wed, Mar 13 Mid-term Exam #2
Fri, Mar 15 Student Oral Critiques
Thur, Mar 21  Final paper due by noon

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