Course: BIOEN 498: Advanced Drug Delivery

Credits: 3

Instructor: Suzie H. Pun

Texts and Supplemental Materials: Relevant articles will be sent to the class prior to lectures.

UW Catalog Description: This course is designed to provide students with an understanding of the current state of the art for advanced drug delivery with a particular focus on biologic drugs (proteins, peptides and nucleic acids). The course will first cover the major families of biologic drugs, major challenges associated with their delivery and specific disease applications for these drugs.

Prerequisites by Course: BIOEN 491

Prerequisites by Topic: Organic Chemistry, Cell Biology, Drug Delivery

Required or Elective: Elective

Specific Outcomes: By the end of this course, students will:

  1. Understand the barriers to delivery of biologic drugs,
  2. Know current best practice in biologic drug delivery, and
  3. Be able to critically analyze new emerging technologies in this area.

Outcomes Addressed by this Course:  We will have weekly literature review followed by discussion/brainstorming led by students of the class starting the 3rd week of class. Grades will be determined based on this presentation and on class participation.  As such, this course contributes to students achieving competency in outcomes (i) a recognition of the need for, and an ability to engage in life-long learning, (j) a knowledge of contemporary issues, and (g) an ability to communicate effectively.  The specialized knowledge on advanced drug delivery imparted through this class contributes to the preparation of our students to reach the Program Educational Objective of earning advanced degrees and/or obtain employment in bioengineering-related fields, such as medicine, device development, or biotechnology and contributing to responsible development of new technical knowledge.

 Topics Covered:

  1. Biologics (Proteins, Genes, Oligonucleotides)
  2. Major barriers to drug delivery
  3. Cell and tissue targeting
  4. Immune response
  5. Cancer, vaccine, cardiovascular, and CNS applications
  6. Literature review

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