The Pasupathy lab has a new paper in eLife today (Sept 19th), authors Amber Fyall, Yasmine El-Shamayleh, Hannah Choi, Eric Shea-Brown and Anitha Pasupathy, show how brain areas involved in vision and cognition may communicate when trying to recognize partially hidden shapes. Click here to read it.
Congratulations to Molecular Medicine and Mechanisms of Disease student Nik Jorstad, Molecular and Cellular Biology students, Matt Wilken, Leah VandenBosch, and postdoctoral fellow, Stefanie Wohl in Tom Reh's lab, their collaborators, Takeshi Yoshimatsu (Acting Instructor) in Rachel Wong's lab, and Will Grimes (Acting Instructor) in Fred Rieke's lab (PBIO) on their article published in Nature today (7/26/2017)! They showed for the first time that functional neurons can be regenerated in the adult mouse retina. Click here to read it. Link to news coverage regarding the article.
This project is driven by their novel discovery of a secondary myogenic lineage in extraocular muscles (EOMs) that specifies the EOM orbital layer and may contribute to the unique sparing of this muscle group in Duchenne muscular dystrophy and in dystrophin-null animal models. The immediate aim is to establish and evaluate several Cre/loxP mouse models for the impact on the emergence of the EOM secondary myogenic lineage. The results could contribute to breakthrough findings refining our understanding of mechanisms involved in eye muscle functional specification and the sparing of the EOMs in muscular dystrophy.