Dr. Walsh has had a long and productive career in protein chemistry. Of particular importance is his early work improving strategies for automated sequencing of proteins and identifying posttranslational modifications. These analyses contributed to concepts regarding the evolution of protein structure and function through gene duplication, the gradual divergence of their sequences, and gene fusions. He was among the first to draw attention to the power of mass spectrometry techniques for protein characterization. Among his recent accomplishments are the development of a method for direct sequence analysis of proteins using in-source fragmentation, and for locating and identifying protein posttranslational modifications. The Pehr Edman Award is given to individuals whose efforts have significantly advanced the fields of protein chemistry, protein structure analysis, or proteomics. The award honors and commemorates the work of Pehr Edman, the Swedish chemist principally responsible for developing the chemistry for sequencing proteins by removing amino acids from the amino terminus one at a time. The Award is given in conjunction with Methods in Protein Structure Analysis (MPSA) meetings, which are sponsored by the International Association for Protein Structure Analysis and Proteomics. The 2002 awards, which are supported by Applied Biosystems, Inc., were presented at MPSA2002 in Valencia, Spain, September 8-12, 2002. |