Welcome to the QBI Lab!
Developing quantitative MRI techniques to improve diagnosis and treatment of breast cancer
Learn More

About Us

The QBI lab brings together a world class team of physicians and scientists to investigate new imaging techniques and to develop robust quantitative imaging biomarkers.

UW Radiology Logo

UW Radiology

The Department of Radiology at the University of Washington is an academic department providing highly specialized care to patients through state-of-the-art diagnostic imaging or imaging-guided therapies.

SCCA Logo

Seattle Cancer Care Alliance

Seattle Cancer Care Alliance is a world-class cancer treatment center that unites doctors from Fred Hutchinson Cancer Research Center, UW Medicine and Seattle Children's.

Research

Our imaging research addresses multiple clinical challenges related to breast cancer. We are utilizing new imaging approaches, such as advanced diffusion-weighted and contrast-enhanced MRI techniques, novel post-processing tools, and working to translate promising technologies to clinical practice through validation in clinical trials.
Click here for a list of publications.

Diagnostics

Research Topic

Screening

Research Topic

Treatment Response

Research Topic

New Technologies

Research Topic

Active Studies

  • DW-MRI tailored for early detection of mammographically occult breast cancer in women with dense breasts

    In this study, we aim to implement novel technical optimizations to improve breast cancer detectability on DWI in women with dense breasts. Results of this study will provide valuable information as to the potential of using DWI as a screening tool that complements x-ray mammography and is faster, less expensive, and safer than DCE MRI for earlier detection of malignancy in women with dense breasts.

  • MRI Characterization of Biological Risk of Ductal Carcinom in Situ (DCIS)

    The objective of this project is to develop robust advanced multiparametric breast MRI markers to characterize DCIS risk prior to tissue sampling. Successful results of this study could lead to a decrease in unneccessary biopsies of calcifications and provide accurate assessments of DCIS risk of progression to invasive disease and recurrence after treatment.

  • Functional MRI Signatures of Immune Response to Targeted Breast Cancer Therapy

    The goal of this research is to improve breast cancer treatment by identifying novel imaging markers of tumor immune response. Exciting advances in immunotherapeutic treatment approaches increase the need for new tools to quantify response and assess treatment efficacy in vivo.

  • FEXI (Filter Exchange Imaging)

    Diffusional exchange of water between micro-environments with different apparent diffusivities, e.g. intra- and extra-cellular space, can be quantified by filter exchange imaging (FEXI). In cell suspensions, the apparent exchange rate (AXR) measured by FEXI is closely related to permeability of cell membranes. AXR may therefore provide a unique assessment of tissue organization and physiology, and constitute a valuable new biomarker for breast lesion characterization.

  • Advanced Methods for Breast Cancer Screening

    CESM (contrast-enhanced spectral mammography) and ABMR (abbreviated breast MRI). The purpose of this study is to learn if two new breast cancer screening tests are effective in detecting breast cancer. If these tests are similar to standard breast MRI, they may offer additional screening options at lower cost for more women.

  • Deep Learning

    Breast MRI is the most sensitive modality for detecting breast cancer, but suffers from high costs, low specificity, and high benign biopsy rate. The goal of this work is to determine whether a deep learning approach can improve specificity while maintaining high sensitivity for detecting cancer on breast MRI.

Our Team

Savannah Partridge, PhD

Principle Investigator

Dr. Habib Rahbar, MD

Clinical Director

Sana Parsian, MD

Research Fellow

Yifan Wu, MS

Research Scientist/Engineer

Debosmita Biswas, MS

Research Scientist/Engineer

Michaela DelPriore, Senior Undergraduate

Research Associate

Adrienne Kim, BS

Research Coordinator

Madeline Dang, MPH

Research Coordinator

Neal Shekar, Senior Undergraduate

Research Associate

Ginger Lash, Senior Undergraduate

Research Associate

Contact Us

Experience for Students

breastMR@uw.edu

Seattle Cancer Care Alliance
825 Eastlake Ave E, G2-600
P.O. Box 19023
Seattle,Wa 98102

Research internships are available for students interested in science, engineering or medical careers. Computer programming experience helpful but not required. Successful students will co-author conference abstracts and scientific journal publications of their work. Hours are flexible, with minimum of 6+ hours/week and 6 month commitment. Positions are available throughout the year.
Job duties include:

  • Use existing tools to analyze images and take measurements
  • Compile and organize human subject data in spreadsheets for analysis
  • Perform statistical testing on data
  • Assist in developing and testing new MRI image acquisition techniques and analysis software
  • Survey and summarize research literature
Copyright © University of Washington - Quantitative Breast Imaging Lab 2018