Synapt G2 HDMS
The Bush Lab has a Waters Synapt G2 HDMS quadrupole/ion-mobility/time-of-flight hybrid mass spectrometer. In addition to the standard features, our Synapt G2 is equipped with electron transfer dissociation capabilities, a quadrupole mass filter capable of selecting precursor ions that have m/z of up to 32k, and a radio-frequency confining drift cell developed by our lab to accurately probe the shapes of protein complexes. This instrument enables the characterization of stoichiometry, subunit interactions, and shapes for heterogeneous, dynamic, and/or membrane-bound protein complexes that have masses of up to ~1 MDa.
Waters Synapt G1 HDMS
We have a Waters Synapt HDMS quadrupole/ion-mobility/time-of-flight mass spectrometer. The quadrupole mass filter on this instrument can select precursor ions that have m/z of up to 32k.
Additional Quadrupole/Time-of-Flight Mass Spectrometers
We also have a Waters Q-TOF Premier and a Waters Q-TOF API US, which we use primarily for instrument development projects.
Agilent High-Performance Liquid Chromatography System
Bio-Rad DuoFlow 10 Protein Purification System