Instruments

Synapt G2 HDMS
Bush Lab Synapt G2 HDMS

The Bush Lab has a Waters Synapt G2 HDMS quadrupole/ion-mobility/time-of-flight hybrid mass spectrometer. In addition to the standard features, our Synapt G2 is equipped with electron transfer dissociation capabilities, a quadrupole mass filter capable of selecting precursor ions that have m/z of up to 32k, and a radio-frequency confining drift cell developed by our lab to accurately probe the shapes of protein complexes. This instrument enables the characterization of stoichiometry, subunit interactions, and shapes for heterogeneous, dynamic, and/or membrane-bound protein complexes that have masses of up to ~1 MDa.

Sam Allen and Ken Laszlo using our Synapt G2.

Sam Allen and Ken Laszlo using our Synapt G2.

Waters Synapt G1 HDMS

We have a Waters Synapt HDMS quadrupole/ion-mobility/time-of-flight mass spectrometer. The quadrupole mass filter on this instrument can select precursor ions that have m/z of up to 32k.

Additional Quadrupole/Time-of-Flight Mass Spectrometers

We also have a Waters Q-TOF Premier and a Waters Q-TOF API US, which we use primarily for instrument development projects.

Agilent High-Performance Liquid Chromatography System

Sam Marionni using our HPLC for on-line  seperations.

Sam Marionni using our HPLC for on-line separations.

 

Bio-Rad DuoFlow 10 Protein Purification System

Bio-Rad DuoFlow 10

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