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  1. Nonspecific Aggregation in Native Electrokinetic Nanoelectrospray Ionization. Kimberly L. Davidson; Derek R. Oberreit; Christopher J. Hogan; Matthew F. Bush. Int. J. Mass Spectrom. 2016, DOI: 10.1016/j.ijms.2016.09.013. (Link)


  1. Analysis of Native-Like Ions using Structures for Lossless Ion Manipulations. Samuel J. Allen, Rachel M. Eaton, and Matthew F. Bush. Anal. Chem. 2016, 88, 9118–9126. (Link)


  1. Radio-Frequency (RF) Confinement in Ion Mobility Spectrometry: Apparent Mobilities and Effective Temperatures. Samuel J. Allen, Matthew F. Bush. J. Am. Soc. Mass Spectrom. 2016, DOI: 10.1007/s13361-016-1479-9. (Link)


  1. Toward a Rational Design of Highly Folded Peptide Cation Conformations. 3D Gas-Phase Ion Structures and Ion Mobility Characterization. Robert Pepin, Kenneth J. Laszlo, Aleš Marek, Bo Peng, Matthew F. Bush, Helène Lavanant, Carlos Afonso, František Tureček. J. Am. Soc. Mass Spectrom. 2016, 27, 1647–1660. (Link)


  1. Folding of Protein Ions in the Gas Phase after Cation-to-Anion Proton-Transfer Reactions (CAPTR). Kenneth J. Laszlo, Eleanor B. Munger, and Matthew F. Bush. J. Am. Chem. Soc. 2016, 138, 9581–9588. (Link|PUBMED)


  1. Does Thermal Breathing Affect Collision Cross Sections of Gas Phase Peptide Ions? An Ab Initio Molecular Dynamics Study. Robert Pepin, Alessio Petrone, Kenneth J. Laszlo, Matthew F. Bush, Xiaosong Li, and František Tureček. J. Phys. Chem. Lett. 2016, 7, 2765–2771. (Link)


  1. Infrared Laser Activation of Soluble and Membrane Protein Assemblies in the Gas Phase. Victor A. Mikhailov, Idlir Liko, Todd H. Mize, Matthew F. Bush, Justin L.P. Benesch, Carol V. Robinson. Anal. Chem. 2016, 88, 7060–7067. (Link)


  1. Ion mobility mass spectrometry of peptide, protein, and protein complex ions using a radio-frequency confining drift cell. Samuel J. Allen, Kevin Giles, Tony Gilbert, Matthew F. Bush. Analyst 2016141, 884-891. (Link|PUBMED|PDF)


  1. Analysis of Native-Like Proteins and Protein Complexes Using Cation to Anion Proton Transfer Reactions (CAPTR). Kenneth J. Laszlo; Matthew F. Bush. J. Am. Soc. Mass Spectrom. 2015, 26, 2152-2161. (Link|Link to PUBMED)
    • This article was highlighted in ASMS News and Views (Link)


  1. Collision cross section calibrants for negative ion mode traveling wave ion mobility-mass spectrometry. Jay G. Forsythe, Anton S. Petrov, Chelsea A. Walker, Samuel J. Allen, Jarrod S. Pellissier, Matthew F. Bush, Nicholas V. Hud, Facundo M. Fernández. Analyst 2015, 140, 6853-6861. (Link|PUBMED)


  1. Electron Transfer Reduction of the Diazirine Ring in Gas-Phase Peptide Ions. On the Peculiar Loss of [NH4O] from Photoleucine. Aleš Marek, Christopher J. Shaffer, Robert Pepin, Kristina Slováková, Kenneth J. Laszlo, Matthew F. Bush, František Tureček. J. Am. Soc. Mass. Spectrom. 2015, 26, 415-431. (Link|PUBMED)


  1. Comprehensive Analysis of Gly-Leu-Gly-Gly-Lys Peptide Dication Structures and Cation-Radical Dissociations Following Electron Transfer: From Electron Attachment to Backbone Cleavage, Ion-Molecule Complexes, and Fragment Separation Robert Pepin, Kenneth J. Laszlo, Bo Peng, Aleš Marek, Matthew F. Bush, František Tureček. J. Phys. Chem. A 2014, 118, 308–324. (Link|PUBMED)


  1. Effects of Polarity on the Structures and Charge States of Native-like Proteins and Protein Complexes in the Gas Phase Samuel J. Allen, Alicia M. Schwartz, Matthew F. Bush. Anal. Chem. 2013, 85, 12055–12061. (Link|PUBMED)


  1. Hexamers of the Type II Secretion ATPase GspE from Vibrio cholerae with Increased ATPase Activity Connie Lu, Stewart Turley, Samuel T. Marionni, Young-Jun Park, Kelly K. Lee, Marcella Patrick, Ripal Shah, Maria Sandkvist, Matthew F. Bush, Wim G.J. Hol. Structure 2013, 21, 1707–1717. (Link|PUBMED)


  1. Gas-Phase Structures of Phosphopeptide Ions: A Difficult Case František Tureček, Christopher L. Moss, Ioannis Pikalov, Robert Pepin, Kerim Gulyuz, Nicolas C. Polfer, Matthew F. Bush, Jeffery Brown, Jonathan Williams, Keith Richardson. Int. J. Mass Spectrom. 2013, 354–355, 249–256 . (Link)


  1. Electron Transfer Dissociation of Photolabeled Peptides. Backbone Cleavages Compete with Diazirine Ring Rearrangements Aleš Marek, Robert Pepin, Bo Peng, Kenneth J. Laszlo, Matthew F. Bush, František Tureček. J. Am. Soc. Mass Spectrom. 2013, 24, 1641–1653. (Link|PUBMED)


  1. SCFFBXL3 ubiquitin ligase targets cryptochromes at their cofactor pocket Weiman Xing, Luca Busino, Thomas R. Hinds, Samuel T. Marionni, Nabiha H. Saifee, Matthew F. Bush, Michele Pagano, Ning Zheng. Nature 2013496, 64–68. (Link|PUBMED)

Ion Mobility of Peptide Ions

  1. Ion mobility mass spectrometry of peptide ions: effects of drift gas and calibration strategies Matthew F. Bush, Iain D. G. Campuzano, Carol V. Robinson. Anal. Chem. 2012, 84, 7124–7130. (Link|PUBMED)

  1. Dissecting Heterogeneous Molecular Chaperone Complexes Using a Mass Spectrum Deconvolution Approach Florian Stengel, Andrew J. Baldwin, Matthew F. Bush, Gillian R. Hilton, Hadi Lioe, Eman Basha, Nomalie Jaya, Elizabeth Vierling, Justin L.P. Benesch. Chem. Biol. 2012, 19, 599–607. (Link|PUBMED)

  1. Traveling-wave ion mobility mass spectrometry of protein complexes: accurate calibrated collision cross-sections of human insulin oligomers Rune Salbo, Matthew F. Bush, Helle Naver, Iain Campuzano, Carol V. Robinson, Ingrid Pettersson, Thomas J. D. Jørgensen, Kim F. Haselmann. Rapid Commun. Mass Spectrom. 2012, 26, 1181–1193. (Link|PUBMED)

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  1. Assigning Structures to Gas-Phase Peptide Cations and Cation-Radicals. An Infrared Multiphoton Dissociation, Ion Mobility, Electron Transfer, and Computational Study of a Histidine Peptide Ion Christopher L. Moss, Julia Chamot-Rooke, Edith Nicol, Jeffery Brown, Iain Campuzano, Keith Richardson, Jonathan P. Williams, Matthew F. Bush, Benjamin Bythell, Bela Paizs, Frantisek Turecek. J. Phys. Chem B 2012, 116, 3445–3456. (Link|PUBMED)

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  1. Charge-State Dependent Compaction and Dissociation of Protein Complexes – Insights from Ion Mobility and Molecular Dynamics Zoe Hall, Argyris Politis, Matthew F. Bush, Lorna J. Smith, and Carol V. Robinson. J. Am. Chem. Soc. 2012, 134, 3429–3438. (Link|PUBMED)

  1. Structural Characterization of Drug-like Compounds by Ion Mobility Mass Spectrometry: Comparison of Theoretical and Experimentally Derived Nitrogen Collision Cross-sections Iain Campuzano, Matthew F. Bush, Carol V. Robinson, Claire Beaumont, Keith Richardson, Hyungjun Kim, Hugh I. Kim. Anal. Chem. 2012, 84, 1026-1033. (Link|PUBMED)
    • The source code for the theoretical approaches used in article can be obtained by contacting Matt Bush (

Unfolding Landscapes & Noncovalent Adducts

  1. Gas-Phase Protein Assemblies: Unfolding Landscapes and Preserving Native-Like Structures Using Noncovalent Adducts Joanna Freeke, Matthew F. Bush, Carol V. Robinson, Brandon T. Ruotolo. Chem. Phys. Lett. 2012524, 1-9. (Link)

  1. Collision Cross Sections of Proteins and their Complexes: a Calibration Framework and Database for Gas-Phase Structural Biology Matthew F. Bush, Zoe Hall, Kevin Giles, John Hoyes, Carol V. Robinson, Brandon T. Ruotolo. Anal. Chem. 2010, 82, 9557-9565. (Link|PUBMED)

  1. Defining the mechanism of polymerization in the serpinopathies Ugo I. Ekeowa, Joanna Freeke, Elena Miranda, Bibek Gooptu, Matthew F. Bush, Juan Pérez, Jeff Teckman, Carol V. Robinson, David A. Lomas. Proc. Natl. Acad. Sci. U.S.A. 2010, 107, 17146–17151. (Link|PUBMED)

Earlier Publications

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