Comparative Effectiveness, Cost and Outcomes Research Center


The mission of the Comparative Effectiveness, Cost and Outcomes Research Center (CECORC) is to discover the most cost-effective, evidence-based approaches to improving the health of patients and populations, and to identify ways to put these improvements into practice. CECORC’s primary emphasis is to evaluate medical devices, diagnostics and medical procedures.  The research group carries out this mission by conducting innovative research, participating in clinical, database, other comparative studies, advancing the state of scientific knowledge through publications and education initiatives, and improving methodologies for studying the costs, quality and outcomes of medical care. CECORC investigators are committed to promoting collaborative, multidisciplinary cost and outcomes research, and to providing opportunities for fellows, residents and students to participate in comparative effectiveness, cost-effectiveness, and outcomes research.


CECORC brings together diverse investigators who have a common interest in health technology assessment and evaluating the value of medical technologies and procedures. Having a community of researchers and shared resources most importantly enhances the ability of individuals within the group to obtain extramural funding related to health services research in their respective fields. CECORC is a tangible center that has a strong publication record whose investigators are nationally and internationally recognized for their research. CECORC fills a much needed niche at the University of Washington and regionally with its focus on the evaluation of medical technologies and procedures. Every Department and School involved with the health sciences is a potential collaborator. From a health policy perspective, State and Federal initiatives are now promoting comparative effectiveness and other type of health services research. In addition, private and public payers are increasing their standards for organizations to demonstrate evidence of value and appropriateness for medical products and procedures. Reimbursement policies are becoming more value-based, which directly relates to the core organizational objectives of CECORC, i.e., developing, evaluating, and disseminating evidence of value for medical technologies.


CECORC brings together researchers conducting cost-effectiveness and outcomes studies that are interdisciplinary and emphasize cost as well as outcome for the comparative evaluation of approaches to existing and new technologies and procedures. In addition, CECORC investigators collaborate with local, regional, national and international health services research, health outcomes, and health policy groups.

Sample of Current Projects

       Musculoskeletal Projects

  • Coordinating center for a randomized controlled trial (RCT) of vertebroplasty
  • RCT for carpal tunnel syndrome diagnosis and treatment
  • Cohort study for treatment of discogenic back pain
  • Epidemiology of spinal surgery: rates and trends
  • Epidemiology of Epidural Steroid Injection Use; Retrospective Study of The Impact of Ambulatory Surgical Center Use on Utilization and Costs of Services in the Medicare Population
  • Synthesis of CT and MR images of the cervical spine


  • RCT for minimally invasive adjunctive treatment for sleep apnea (TURBO Trial)
  • Case control study investigating injury and bankruptcy
  • Seattle Sleep Cohort Study; Sleep Surgery Cohort Study
  • Sleep Apnea Severity Index validation study; national community-based multi-site study of sleep surgery outcomes (SLEEP Study)
  • RCT for chronic sinusitis and depression (SAD Trial)
  • Cohort study of olfactory disturbance of rhinosinusitis (ODOR Study)
  • Cost-effectiveness assessment of RCT for malocclusion treatment.


CECORC is housed in offices located in the Patricia Steel Building (401 Broadway) near Harborview Medical on First Hill in Seattle, WA. These offices are the home for most CECORC research projects, and the location from which clinical and field staff are directed.

Faculty Investigators

  • Brian W. Bresnahan, PhD - Radiology and Pharmacy
  • Greg E. Davis, MD MPH - Otolaryngology / Head and Neck Surgery
  • Richard A. Deyo, MD MPH - OHSU
  • Janna Friedly, MD MPH - Rehabilitation Medicine
  • Patrick J Heagerty, PhD - Biostatistics
  • Stanley Herring, MD - Rehabilitation Medicine
  • Michel Kliot, MD - Neurological Surgery
  • John Ney, MD - Neurology
  • Judith Turner, PhD - Psychiatry and Behavioral Sciences


  • Medicine (Neurological Surgery, Otolaryngology / Head and Neck Surgery, Physical Medicine and Rehabilitation, Psychiatry and Behavioral Sciences, Radiology)

  • Public Health (Biostatistics, Health Services)

  • Pharmacy (Pharmaceutical Outcomes Research and Policy Program)

  • Pharmacy (Pharmacy)

Box 359736, PSB Suite 5076
325 Ninth Ave
Seattle, WA 98104
© 2002-2005
Comparative Effectiveness, Cost and Outcomes Research Center
voice: (206) 744-1800
patient message line: (206) 744-1816
fax: (206) 744-9889