James H. Caldwell, M.D. is Professor of Medicine and Radiology and Adjunct Professor of Bioengineering. He received his medical degree from the U. of Missouri-Columbia and completed his residency in Medicine and his Cardiology training at the U. of Washington. He spent several years in the Veteran’s Administration Career Development program developing expertise in cardiovascular imaging in experimental animal models of disease and in humans.
His research is focused on: a) development/validation of technical tools for myocardial perfusion imaging with single-photon emission, positron emission and x-ray computed tomography and the clinical application of these modalities for diagnosis and prognosis; b) the development and validation of radiotracers to evaluate in vivo function of the cardiac pre- and post-synaptic sympathetic nervous system and the clinical application in the management of congestive heart failure; and mathematical modeling of radiotracer kinetics for quantification of in vivo metabolism, receptor function and flow in pathophysiologic processes.