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University of Washington
School of Medicine
Box 358050
850 Republican Street
Brotman Building 453
Seattle, WA 98195-8050

Brian Hawkins, PhD

Publications

Brian Hawkins

Dr. Hawkins is an Assistant Professor in the Department of Anesthesiology and Pain Medicine and an adjunct Assistant Professor in Pathology at the University of Washington. Dr. Hawkins received his PhD from the Virginia Polytechnic Institute and State University and completed his postdoctoral training at the University of Pennsylvania, where he investigated how mitochondria integrate and translate calcium signaling into a cellular response.

Dr. Hawkins is currently based in the Mitochondria and Metabolism Center at the University of Washington South Lake Union Campus. The Hawkins Lab has several projects that aim to delineate how mitochondria contribute to overall cellular function and the development of human disease. These projects include:

1) Evaluation of how endothelial mitochondrial bioenergetics impact the function of blood vessels, and how mitochondrial dysfunction contributes to the development of cardiovascular disease; 2) Definition of the discrete role of mitochondrialoxidants in cardiovascular pathology; 3) The identification and characterization of mitochondrial signaling metabolites and their downstream targets; and 4) Examination of the therapeutic potential of mitochondrial functional manipulation during ischemic organ damage.

Dr. Hawkins' lab utilizes multidisciplinary approaches that combine advanced imaging and molecular techniques with classical biochemical analyses in order to evaluate mitochondrial function both in vitro and in vivo.