Overview
Contact

Services

• Genotyping
  
  
• Quantitative Assays
  • Gene Expression Assays (mRNA)
  • Transfection Efficiency Assays
  • Nuclear Run-on Assays
  • Gene Dosage Assays
    
    
• DNA Sequencing
  
  
• Microsatellite Analyses
  
  
• Microarray Services Unit
  
  
• Bioinformatics Services Unit
  • Experimental Design
  • Statistical Analysis

Overview
A principal CEEH theme is to understand the importance of gene-environment interactions (ecogenetics) in the causes of chronic diseases. Research from various laboratories, including those of CEEH investigators, has established that human populations possess small genetic differences (polymorphisms) in many enzyme activities of toxicological relevance. Because the CEEH is committed to promoting human population-based studies, it is essential to have the laboratory facilities to conduct large-scale molecular epidemiology studies. In addition, ongoing technological advances continue to facilitate the evolution of research capabilities in the field of pharmacogenetics (gene-drug interactions) and toxicogenetics (gene-toxic substance interactions). These needs and developments, along with current developments in genome science, form the basis of the Functional Genomics Laboratory's mission: to provide a service facility for CEEH investigators that efficiently performs genetic analysis of large numbers of samples (high-throughput) and correlates the data to the incidence of environmentally related disease.

Since its formation in 1995, the Functional Genomics Laboratory Facility Core has consistently increased the number and types of genotyping assays available, continued the development and testing of new molecular biology-related instrumentation and methodologies, and incorporated additional molecular biology-associated computer software.

Contact
Federico Farin, Core Manager
freddy@u.washington.edu
(206) 685-7285