Facility Core #1: Functional Genomics & Proteomics
The Functional Genomics and Proteomics Lab provides state-of-the-art genomics and proteomics based technologies that can be used to investigate gene-environment interactions in the context of basic environmental health sciences research and population-based studies. The Functional Genomics and Proteomics Laboratory is a shared resource that allows CEEH investigators access to the latest technology and enables them to perform cutting-edge research.
The core provides:
- Access to advanced nucleic acids diagnostics instrumentation center with multi-user access to automated Sanger DNA sequencing, genotyping/haplotyping services, gene expression profiling (mRNA and microRNA), TaqMan based quantitative gene expression analysis, and other DNA and RNA-based analytical technologies.
- Technical support and pipeline access Next Generation Sequencing capabilities that allow a number of applications, including targeted re-sequencing for genotyping analysis, Chromatin Immunoprecipitation based sequencing, transcriptome sequencing, and methylation analysis.
- Custom specialized microarray platforms (e.g. microarray-based genomic enrichment, microRNA arrays)
- Access to state-of-the-art proteomic instrumentation for automated protein identification, and other protein-based analytical methodologies.
- Consultation on meaningful integration of genomic, proteomic and metabolomic approaches to individual research projects.
- Collaboration BioInformatics and Biostatistics Services Core to facilitate efficient study design and overall coordination of a project, including validation of data that has been analyzed by Bioinformatics and Biostatistics Core
- Access to the TaqMan OpenArray Genotyping System that will allow investigators to perform faster and more cost-effective high-sample-throughput genotyping studies
Director: Jing Zhang, M.D., Ph.D.
zhangj@u.washington.edu
206-897-5245
Laboratory Manager: Federico Farin, M.D.
freddy@u.washington.edu
206-685-7285