Area of Research Emphasis (ARE) #6:
Omics Technologies & Bioinformatics
Overview: Bioinformatics and genomics technologies are transforming many areas of research and environmental health is no exception. Researching gene-environment interactions requires advanced bioinformatics and biostatistics methodologies in both designing experiments and analyzing results. Researchers at the CEEH are working with experts in biostatistics and genome sciences to effectively utilize bioinformatics and "-omics" methodologies (genomics, proteomics, and metabolomics) in their studies. Investigators are continually seeking to develop new and better approaches to handling the large and complex data sets that gene-environment studies produce.
CEEH Connections: Eleven faculty affiliated with the CEEH are working in this area of research emphasis. Researchers represent a broad range of interests and expertise under the leadership of Bruce Weir. Dr. Weir is head of the Department of Biostatistics and a leading expert in the field of bioinformatics for genomics, especially genome-wide association studies (GWAs). David Goodlett, Walter Ruzzo, Jing Zhang, and William Noble specialize in proteomics and the bioinformatics analysis of proteomics data. Kathleen Kerr and Roger Bumgarner are involved with the use of RNA expression data in toxicogenomics studies. Finally, Debbie Nickerson and John Stamatoyannopoulos contribute their expertise in many areas of genome sciences to the work of the Center.
ARE Director:
Dr. Dr. Bruce Weir, UW Dept. of Biostatistics
bsweir@u.washington.edu
206-221-7947