Services

Our sub-Core provides a specimen collection service for approved investigators who lack the funds or infrastructure needed to procure the clinical specimens necessary for their research.

The HIV Negative Registry is a registry of HIV-negative individuals who are interested in participating in HIV-related research and serving as controls when indicated. 

We support screening and recruitment of eligible HIV-Infected patients into clinical and pathogenesis research studies via a dedicated research nurse.

This service is available to investigators to increase enrollment of HIV+ patients into research studies. Lindsay Legg, the HIV research coordinator, is effective at increasing enrollment in HIV studies. Ms. Legg reviews the records of UW HIV Registry patients visiting the HMC Madison Clinic and refers those who qualify to the appropriate research coordinator for enrollment. 

The HIV Specimen Repository is a collection of frozen plasma and peripheral blood mononuclear cells (PBMC) specimens donated by HIV infected patients cared for at the University of Washington HIV clinics (the Madison and Roosevelt Virology Clinics).

Participating patients are asked to donate 30 mL of blood one to three times each year. Blood is separated into plasma and PBMC fractions and frozen in aliquots of 1.5 mL (plasma) or 5 million cells (PBMC) and stored at the Harborview Retrovirology Laboratory.

A wide variety of virological markers for HIV disease and progression are available through this Core.

Translational Research Subcore

Right Column

Enhanced Data and
Specimen Collection
Service

The Translational Research Subcore provides a specimen collection and storage service for approved investigators who lack the funds or infrastructure needed to procure the clinical specimens necessary for their research. 

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About

The Translational Research Subcore helps investigators by:

  • Promoting translational HIV research through the use of our HIV Specimen Repository, which contains plasma, serum, and PBMC specimens linked to extensive clinical data, and our Enhanced Data and Specimen Collection Service, which supports the prospective collection of clinical samples not contained in the Repository.
  • Supporting the screening and recruitment of HIV-infected patients (or HIV-negative controls) into clinical, laboratory, and socio-behavioral research studies through a dedicated research nurse at the Harborview and University of Washington HIV clinics.
  • Assisting with study implementation including the provision of clinical space, phlebotomy etc.

Both basic and clinical scientists at CFAR benefit from the services and consultations of the subcore. Our dedicated research nurse at Harborview HIV clinic expedites the screening and enrollment of appropriate patients into new translational studies.

With our HIV Specimen Repository—which contains frozen plasma, serum, and PBMC specimens linked to extensive clinical data, we offer immediate access to large numbers of well characterized samples for translational studies. Contributions to this repository comprise a rich longitudinal collection of samples that reflect serial specimen donations (2-3X/year) with linkage to health data from electronic medical records, including clinical, virologic, immunologic, and demographic factors.

Through our Enhanced Data and Specimen Collection Service, we provide an infrastructure for lab-based investigators to obtain clinical specimens including rectal or GI biopsies.

Subcore faculty can assist with design, methods, quality assurance, and data interpretation in clinical studies of AIDS/HIV. They can partner with CFAR researchers to develop novel laboratory methods for determining viral loads in various compartments and correlating these HIV markers with clinical outcomes.

Services
Services

Our sub-Core provides a specimen collection service for approved investigators who lack the funds or infrastructure needed to procure the clinical specimens necessary for their research.

The HIV Negative Registry is a registry of HIV-negative individuals who are interested in participating in HIV-related research and serving as controls when indicated. 

We support screening and recruitment of eligible HIV-Infected patients into clinical and pathogenesis research studies via a dedicated research nurse.

This service is available to investigators to increase enrollment of HIV+ patients into research studies. Lindsay Legg, the HIV research coordinator, is effective at increasing enrollment in HIV studies. Ms. Legg reviews the records of UW HIV Registry patients visiting the HMC Madison Clinic and refers those who qualify to the appropriate research coordinator for enrollment. 

The HIV Specimen Repository is a collection of frozen plasma and peripheral blood mononuclear cells (PBMC) specimens donated by HIV infected patients cared for at the University of Washington HIV clinics (the Madison and Roosevelt Virology Clinics).

Participating patients are asked to donate 30 mL of blood one to three times each year. Blood is separated into plasma and PBMC fractions and frozen in aliquots of 1.5 mL (plasma) or 5 million cells (PBMC) and stored at the Harborview Retrovirology Laboratory.

A wide variety of virological markers for HIV disease and progression are available through this Core.

Activities

The Translation Research Subcore has helped accelerate the funding and progress of many important studies - especially smaller pilot studies or those championed by new investigators who have limited budgets or require mentoring with clinical, laboratory, or regulatory aspects of their research.

For a list of our current and upcoming projects, please click here

People
Nina Kim, MD, MSc
Co-Director
 
 
Lisa Frenkel, MD
Associate Director
 
Joan Dragavon
Research Scientist
 
Abby Howell
Core Manager
 
Charlene Hayes
Research Coordinator

Lindsay Legg
Research Nurse

TRS Picture.jpg

Contact

325 9th Ave
UW Box 359929
Seattle, WA 98104
cfarcrc@uw.edu
(206) 744.6430