Capturing Snapshots of the Cell Invasion

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Kelly K. Lee, PhD Assistant Professor, Medicinal Chemistry, University of Washington Location: D209, Turner Auditorium, Health Science Building (HSB), University of Washington Dr. Lee received his A.B. in Physics from Harvard University and his Ph.D. in Biophysics from the Johns Hopkins University. As a postdoctoral fellow in Jack Johnson’s group at the Scripps Research Institute, he studied mechanisms of conformational change in viruses. An NIH K99/R00 award enabled him to pursue investigation of infl uenza virus’s membrane fusion process using cryo-electron microscopy and other biophysical techniques. His research in the Department of Medicinal Chemistry focuses on the structure and dynamics of membrane fusion proteins in influenza and HIV, with the goals of understanding how the specialized glycoprotein machinery mediates membrane remodeling during cell invasion and determining how it interacts with cellular receptors and antibodies. This lecture will also be televised at: Harborview Medical Center: Ninth & Jefferson Building (NJB) - 707 Seattle Children's Research Institute: Pearl Jam Room 806 Building 1 Fred Hutchinson Cancer Research Center: J2-108 Washington State University - Spokane Campus: SAC 343 Washington State University - Pullman Campus: Morrill Hall 124 University of Alaska - Anchorage: CPISB 101D Montana State University: Byker Auditorium Room 3CBB