The Core resource makes experimental design and processing of microarray, high-throughput sequencing and mass-spectrometry based platforms broadly available to researchers across the Center through expertise in data analysis, consulting, training and technology development. The following coordinated initiatives are provided generally at no cost to CFAR members.
1. Consulting - An email help-desk (see below) is staffed for users to submit questions, request meetings to discuss specific analysis strategies, and solicit advice on experiment design and novel research studies.
2. Data processing and analysis - Expertise is provided in the areas of microarray, high-throughput DNA sequencing, genomics, & proteomics data, and for combining data with public bioinformatics resources, including expertise specific to viral sequence analysis (described below).
3. Training - Classes and hands-on computing labs are offered periodically to introduce genomics and proteomics techniques and analysis tools to CFAR staff allowing them to work independently.
4. Technology Development and Acquisition -- As new technologies of likely general use are identified this resource works with other center investigators or shared resources to acquire and deploy those computational techniques. CFAR Investigators with a need to access new computational technologies can request developments through the resource; priority is given to those technologies that will be used by multiple CFAR members, and approval is provided by the scientific steering committee.
5. Development, maintenance, support and access to software: A key aspect of the Core is to provide access to computational tools (some web-based, others standalone) required to interpret sequence data, including phylogenic analysis, classification/clustering, processing RNA- or DNA- sequence data. A current list of software algorithms can be found here: http://indra.mullins.microbiol.washington.edu/ and also here http://matsen.fhcrc.org/software.html .