STD/AIDS Research Training Fellowship Program
Health Metrics & Modeling in HIV/STD Track
Director: Emmanuela Gakidou, PhD, MSc
Overview: The new Health Metrics & Modeling in HIV/STD Track will provide a framework for training in research that
uses emerging modeling and health metrics methodologies to describe HIV/STD-related endpoints, including global disease burden,
targeting interventions, role of combination interventions, and resource allocation. Trainees with these skills have become
increasingly necessary as the field of STD/AIDS research has evolved towards enhanced understanding of the relation between
individual behavior and population level transmission dynamics, the role of sexual and social networks in the spread of infection,
and the need for robust metrics to consistently measure the effects of interventions and funding allocations across settings and
populations. This track seeks to prepare the next generation of investigators to participate in this multi-disciplinary
environment. This track takes advantage of the groundbreaking methodologies developed by Dr. Christopher Murray and his team at
the Institute of Health Metrics & Evaluation (IHME) that have rapidly become standard tools for the measurement of health and
disease-related outcomes worldwide. Their application requires access to a sophisticated skill set that combines elements of
mathematical modeling, economics, and health delivery systems. As global resources become scarcer, the field of implementation
science has grown in stature, and scientists with formal training in this area have become increasingly valuable. The IHME
faculty comprise a world-class and diverse group of researchers who have a strong interest in the HIV/AIDS field in particular,
and many faculty in this track are IHME members.
8 Training Faculty and 1 Junior Training Faculty
Gakidou, Emmanuela PhD, MSc
Track Director, Training Faculty
Research interests are impact evaluation and methods development for analytical challenges in global health. Examples of current
research projects include the evaluation of Avahan (a large HIV-prevention program in India), the development of a time series of
educational attainment for all countries from 1960 to present, the measurement of adult mortality in developing countries, and
the measurement of economic status through health surveys.
Barnabas, Ruanne DPhil, MSc
Research focuses on HIV treatment and prevention, specifically on interventions that reduce HIV viral load, disease progression,
and transmission. Dr. Barnabas' projects use empiric data and mathematical models to better understand HIV clinical progression
and transmission, and estimate the potential impact of HIV interventions at population level. The ultimate aim is to estimate
effective- ness and cost-effectiveness of HIV treatment and prevention interventions to inform clinical trial design.
Goodreau, Steven PhD
Primary research interests are the transmission and evolution of HIV, and also include developing methodologies for the statistical
analysis of social networks and their integration into demographic and epidemiological research. Dr. Goodreau has studied sexual
role versatility among MSM in Peru and the effect of role segregation on HIV prevalence among MSM. He has published modeling work
on commercial sex venues, serosorting, concurrent partnerships, and network structure and HIV phylogenetics.
Lim, Stephen PhD
Dr. Lim conducts work in several research areas, including monitoring the effective coverage of interventions and health systems
and assessing the performance of US county health systems and impact evaluations. He also leads work on understanding health
service delivery constraints as part of the Disease Control Priorities Network (DCPN). His previous work includes a project on
health information system capacity building focusing on burden of disease and cost effectiveness analysis.
Lozano, Rafael MD, MSc
Dr. Lozano is a global expert in causes of death analysis, health systems strengthening, and verbal autopsy methodology. As former
General Director of Health Information at the Ministry of Health (MOH) in Mexico, he coordinated the production of national health
statistics, coordinating information from a number of health sector institutions in Mexico. Dr. Lozano played a critical role in
the construction of Mexico's health reform through a systematic approach to evidence building.
Mokdad, Ali PhD
Dr Mokdad's experience as a survey methodologist gives him expertise in the design, implementation, and interpretation of data
from large-scale household and facility surveys. His research focuses on how integrated surveillance system can be built fan
deleveraged to maximally benefit public health. Surveys are a critical component to any health information system, but frequently
go underutilized. His research examines how surveys can best be deployed to measure key information (e.g. risk factors, facility
costs, prevalence and incidence of key conditions, disparities in health outcomes) in different populations.
MD, DPhil Training Faculty
Dr. Murray is a physician and health economist whose pioneering work has led to the development of a range of new methods and
empirical studies to strengthen the basis for population health measurement, measure performance of public health and medical care
systems, and assess the cost effectiveness of health technologies. As Director of the Institute for Health Metrics and Evaluation
at University of Washington, he leads a team of researchers focused on the areas of health outcomes, health services, financial
and human resources, evaluations of policies, programs and systems, and decision analytics.
Schiffer, Joshua MD, MSc
The aim of Dr. Schiffer's research program is to gain a better understanding of the quantitative features of human pathogens and
immune responses. In collaboration with several colleagues at FHCRC and UW, he designs mathematical models that capture growth and
decay kinetics of infectious organisms. These models attempt to replicate detailed empirical datasets and, in turn, are used to
inform subsequent human studies and laboratory experiments.
Flaxman, Abraham PhD
Junior Training Faculty
With a background in mathematics and theoretical computer science, Dr. Flaxman has conducted research on randomized algorithms,
machine learning, and combinatorial optimization. Recently, research has focused on applications of computer science to global
health metrics. He has also collaborated on research measuring scale up of malaria control efforts in sub-Saharan Africa. He is
also the primary architect of a software tool (DisMod III) that IHME uses to estimate the Global Burden of Disease. Dr. Flaxman
was recently named to MIT's 2012 list of "35 Innovators Under 35.
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