Characterize the challenges and opportunities in the translation process from genomic discovery to health benefits for medically underserved populations.
Define the major investments, goals, core commitments, and benchmarks for success of key stakeholders in the translational process
Identify features of the translational process that increase or decrease opportunities for achieving benefit for underserved populations
Develop methods to build and evaluate university-community and interdisciplinary partnerships, including strategies to identify common ground and promote mutually beneficial research.
Build interdisciplinary communities of practice around central issues of common concern within genomic research, including research policies and practices that facilitate partnership and enhance benefits for underserved populations
Develop and assess tools to identify and evaluate the facilitators and barriers to achieving communities of practice across different stakeholder groups
Develop and evaluate methods to assist policymakers in assessing the clinical utility and appropriate use of genetic tests
Evaluate practice guidelines for a representative set of genetic tests to assess evidence considered, deliberative processes used, and attention to access, cost, and patient values
Evaluate the comparative effectiveness of selected genetic tests using quantitative risk-benefit and cost-effectiveness analyses
Explore the qualitative and quantitative impact of comparative effectiveness data and patient values on decision making by genomics policymakers using a comparative study design
Provide training opportunities to encourage the participation of trainees and researchers from under-represented minorities in the Center’s research agenda and other ELSI research
Stimulate collaborative partnerships that result in additional funded research to address these and related questions.