Analytic Renal Disease Determinants Working Group

Goal

 Our goal is to bring together a multidisciplinary team to think critically about the roots of renal disease disparities among American Indian/Alaska Native (AI/AN) groups and find pathways to health benefit. We will explore the interplay of environmental factors, social determinants, and genetic variation as components of these disparities with an eye toward reducing health disparities in this context and perhaps more broadly.  

We invite participation from a spectrum of disciplines to engage in a monthly discussion focused on reducing renal disease disparities in AI/AN populations. We will examine this issue through the lenses of environmental, social and genetic factors and a set of subtopics relevant to renal disease in affected populations. Examples include the degree and pace of dietary transition, pesticide/herbicide exposure in occupational settings and diet, and genetic susceptibility and resilience. Topics of interest include fetal origins of health and disease, allostatic load and overload, and pharmacogenomics.

Click Here for our topics of discussion.

Click Here for background on using MS Meeting Live.

 

 

When: Monthly meetings October—June, first Friday of the month from 12-2:00pm PT. Bring your lunch!                   

Dates: 2012: 10/5, 11/9, 12/7  2013: 2/1, 3/1, 4/5, 5/3, 6/7

Where: Dept. Bioethics & Humanities, (UW, HSB, room A204). 

Virtual Attendees please email Lorelei for a participation code and click Here for background on using MS Meeting Live.  

To stay in the loop, join our listserv! Contact Lorelei Walker at loreleis@uw.edu.        

 

Aims

Aim #1: Learning Community to examine the question:  “What (if anything) can genetics/genomics contribute to the reduction of renal health disparities?” To answer this question we are using an interdisciplinary focused case study approach to think critically about the roots of renal disease disparities among American Indian/Alaska Native (AI/AN) groups and find pathways to health benefit/action.

Aim #2: Interdisciplinary Process Evaluation: Clarity on process of interdisciplinary learning.

 

Reference Publications

Lenses:

  • Daniel R. Brooks. CKD in Central America: A Hot Issue. 2012. Am J Kidney Dis. 59(4): 481-484
  • Marmot et al. Closing the gap in generation: health equity through action on the social determinants of health. 2008. Lancet 372: 1661-69.
  • Belsky et al. Polygenic Risk, Rapid Childhood Growth, and the Development of Obesity. 2012. Arch Pediatr Adolesc Med:166(6).