Articles Published in Peer-Reviewed Journals 

Click on the topic listed below to see the journal articles published. 

Public Health and Genomics

Family History

Cardiovascular Disease, Cerebrovascular Disease, and Diabetes

Twin Studies

Genetics

Conditions with a Genetic Component

Public Health and Genomics

Harrison TA, Burke W, Edwards KL. The asthma consultative process: a collaborative approach to intergrating genomics into public health practice Preventing Chronic Disease 2005;2;A27

Raup SF, Oehlke KP, Edwards KL. Developing academic-practice partnerships to enhance the integration of genomics into public health: The University of Washington Center for Genomics and Public Health Experience. Preventing Chronic Disease. 2005 Apr; 2(2):A02.

Family History

Kim H, Friedlander Y, Longstreth WT, Jr, Edwards KL, Schwartz, SM, Siscovick DS. Family history as a risk factor for stroke in young women. Am J Prev Med. 2004 Dec;27(5):391-396.

Harrison T, Hindorff LA, Kim H, Wines RCM, Bowen DJ, McGrath B, Edwards KL. Family History of Diabetes as a Potential Public Health Tool. Am J Preventive Med 2003;24:152-9.

Wylie Burke, MD, PhD, Megan Fesinmeyer, Kate Reed, MPH, Lindsay Hampson, Chris Carlsten, MD. Family History as a Predictor of Asthma Risk Am J Prev Med. 2003 Feb;24(2):160-9.

Cardiovascular Disease, Cerebrovascular Disease, and Diabetes

Hutter CM, Austin MA, Farin FM, Viernes HV, Edwards KL, Leonetti DL, McNeely MJ, Fujimoto WY. Association of endothelial lipase gene (LIPG) haplotypes with high-density lipoprotein cholesterol subfractions and apolipoprotein Al plasma levels in Japanese Americans. Atherosclerosis. 2006 Mar; 185 (1): 78-86.

Hindorff LA, Heckbert SR, Psaty BM, Lumley T, Siscovick DS, Herrignton DM, Edwards KL, Tracy RP. Beta(2)-Adrenergic receptor polymorphisms and determinants of cardiovascular risk: the Cardiovascular Health Study. Am J Hypertens. 2005 Mar;18 (3):392-7.

Austin MA, Talmud PJ, Farin FM, Nickerson DA, Edwards KL, Leonetti D, McNeely MH, Viernes HM, Humphries SE, Fujimoto WY. Association of Apolipoprotein A5 variants with LDL particle size in Japanese Americans. Biochim Biophys Acta 2004, 1688(1): p. 1-9.

Austin, M.A., C.M. Hutter, R.E. Zimmern and S.E. Humphries. Familial hypercholesterolemia and coronary heart disease: A HuGE association review. Am J Epidemiol, 160(5): p. 421-429. 2004.

Austin, M.A., C.M. Hutter, R.E. Zimmern and S.E. Humphries. Genetic causes of monogenetic familial hypercholesterolemia: A HuGE prevalence review. Am J Epidemiol, 160(5): p. 407-420. 2004

Hutter, C.M., M.A. Austin and S.E. Humphries. Familial hypercholesterolemia, peripheral arterial disease and troke: A HuGE mini-review. Am J Epidemiol, 160(5): p. 430-435. 2004.

Austin MA, Edwards KL, Monks SA, Koprowicz KM, Brunzell JD, Motulsky AG, Mahaney MC, Hixson MC. Genomewide scan for low-density lipoprotein particle size in familial combined hyperlipidemia and familial hypertriglyceridemia. J Lipid Res, 2003, 44(11): p. 2161-8.

Bis JC, Smith NL, Psaty BM, Heckbert SR, Edwards KL, Lemaitre RN, Lumley T, Rosendal FR. Angiotensinogen MET235Thr polymorphism, ACE inhibitor therapy, and the risk of nonfatal stroke or myocardial infarction in hypertensive patients. Am J Hypterten 2003; 16(12): p 1011-7

Heckbert SR, Hindorff LA, Edwards KL, Psaty BM, Lumley T, Siscovick DS, Tang Z, Kronmal RA, Tracy R. B-2 adrenergic receptor polymorphisms and risk of incident cardiovascular events in the elderly. Circulation 2003;107:2021-4.

Hindorff LA, Heckbert SR, Tracy R, Tang Z, Psaty BM, Edwards KL, Siscovick DS, Kronmal RA, Nazar-Stewart V. Angiotensin II Type 1 receptor polymorphisms in the Cardiovascular Heatlh Study: relation to blood pressure, ethnicity and cardiovascular events. Am J Hypertension 2002;15:1050-6

Austin MA, Zimmern RL, Humphries SE. High "population attributable fraction" for coronary heart disease mortality among relatives in monogenic familial hypercholesterolemia. Genet Med. 2002 Jul-Aug;4(4):275-8.

Kim H, Marcovina SM, Edwards KL, McKnight B, Bradley CM, McNeely MJ, Psaty BM, Brunzell JD, Motulsky AG, Austin MA. Lipoprotein(a) as a risk factor for maternal cardiovascular disease death. Clin Genet 2001;60:188-97.

Pihlajamäki J, Austin M, Edwards K, Laakso M. A major gene effect on fasting insulin and insulin sensitivity in familial combined hyperlipidemia. Diabetes 2001;50:2396-401.

McNeely MJ, Edwards KL, Marcovina SM, Brunzell JD, Motulsky AG, Austin MA. Refining lipoprotein abnormalities in familial combined hyperlipidemia: A twenty year prospective study. Atherosclerosis 2001; 159:471-81

Kamigaki AS, Siscovick DS, Schwartz SM, Psaty BM, Edwards KL, Trivellore RE, Austin MA. Low-density lipoprotein particle size and risk of early-onset myocardial infarction in women. Am J Epidemiol 2001; 153:939-45.

Austin MA, Rodriguez BL, McKnight B, McNeely MJ, Edwards KL, Curb JD, Sharp DS. LDL Particle size, triglyceride and HDL cholesterol as risk factors for coronary heart disease in older Japanese-American men. Am J Cardiol 2000; Am J Cardio 2000;86:412-6.

Austin MA, McKnight B, Edwards KL, Bradley CM, McNeely MJ, Psaty BM, Brunzell JD, Motulsky AG. Cardiovascular disease mortality in the familial forms of hypertriglyceridemia: A twenty-year prospective study. Circulation 2000; 101:2777-82

Talmud PJ, Edwards KL, Turner CM, Newman B, Palmen JM, Humphries SE, Austin MA. Linkage of the cholesteryl ester transfer protein (CETP) gene to LDL particle size: use of a novel tetranucleotide repeat within the CETP promoter. Circulation 2000; 101:2461-6.

Edwards KL, Mahaney MC, Motulsky AG, Austin MA. Pleiotropic genetic effects on low-density lipoprotein size, plasma triglyceride and high density lipoprotein cholesterol in families. Arterioscler, Thromb, Vasc Biol 1999; 19: 2456-64.

Friedlander Y, Kark JD, Sinnreich R, Edwards KL, Austin MA. Inheritance of LDL peak particle diameter: Results from a segregation analysis in Israeli families. Genetic Epidemiol 1999; 16:382-96

Edwards KL, Burchfiel CM, Sharp DS, Curb JD, Rodriguez BL, Fujimoto WY, LaCroix AZ, Vitiello MV, Austin MA. Factors of the insulin resistance syndrome in non-diabetic and diabetic elderly Japanese American men. Amer J Epidemiol 1998; 147:441-7.

Austin MA, Hokanson JE, Edwards KL. Hypertriglyceridemia as a cardiovascular risk factor. Am J Cardio 1998;8:7B-12B.

Austin MA & Edwards KL. Small, dense LDL, the insulin resistance syndrome and noninsulin-dependent diabetes. Curr Opin Lipidology. 1996; 7:167-71.

Austin MA, Mykkanen L, Kuusisto J, Edwards KL, Nelson C, Haffner SM, Pyorala K, Laakso M. A prospective study of small, LDLs as a risk factor for NIDDM in elderly men and women. Circulation 1995; 92:1770-1778.

Austin MA, Paritz-Jarvik G, Hokanson JE, Edwards K. Complex segregation analysis of LDL peak particle diameter. Genetic Epidemiol 1993;10:599-604.

Twin Studies

Afari N, Noonan C, Goldberg J, Edwards K, Gadepalli K, Osterman B, Evanoff C, Buchwald D. University of Washington Twin Registry: construction and characteristics of a community-based twin registry. Twin Res Genet. 2006 Dec; 9(6): 1023-9.

Edwards KL, Talmud PJ, Newman B, Krauss RM, Austin MA. Lipoprotein candidate genes for multivariate factors of the insulin resistance syndrome: A sib-pair linkage analysis in women twins. Twin Research 2001; 4:41-7.

Friedlander Y, Talmud P, Edwards K, Humphries SE, Austin MA. Sib-pair linkage analysis of longitudinal changes in lipoprotein risk factors and lipase genes in women twins. J Lipid Research 2000;41:1302-9 .

Austin MA, Talmud PJ, Luong LA, Haddad L, Day INM, Newman B, Edwards KL, Krauss RM, Humphries SE. Candidate-gene studies of atherogenic lipoprotein phenotype: A sib pair linkage analysis of dizygous (DZ) women twins. Am J Hum Genet 1998;62:406-419.

Edwards KL, Austin MA, Newman B, Mayer E, Selby JV, Krauss RM. Heritability of factors of the Insulin Resistance Syndrome in women twins. Genetic Epidemiol 1997;14:241-53.

Friedlander Y, Austin MA, Newman B, Edwards K, Mayer-Davis EJ, King MC. Heritability of longitudinal changes in coronary heart disease Risk factors in women twins. Am J Hum Genet 1997;60:1502-12.

Austin MA, Friedlander Y, Newman B, Edwards K, Mayer EJ, King MC. Genetic influences on changes in body mass index: A longitudinal analysis of women twins. Obesity Research 1997; 5:326-331.

Mayer E, Zhang D, Newman B, Austin MA, Quesenberry C, Edwards K, Selby JV. Genetic and environmental influences on the insulin resistance syndrome: An analysis of women twins. Am J Epidemiol. 1996;143:323-32.

Edwards KL, Austin MA, Jarvik G. Evidence for genetic influences on smoking in women twins. Clinical Genetics. 1995;47:236-244.

Edwards KL, Austin MA, Newman B, Mayer E, Krauss RM, Selby JV. Multivariate analysis of the Insulin Resistance Syndrome in Women. Arterioscler Thromb. 1994;14:1940-1945.

Austin MA, Newman B, Selby JV, Edwards K, Mayer EJ, Krauss RM. Genetics of low-density lipoprotein subclass phenotypes in women twins: Concordance, heritability and commingling analysis. Arterioscler Thromb. 1993;13:687-695. 

Genetics

Conditions with a Genetic Component

Obesity

Zhang C, Williams MA, Edwards KL, Austin,MA. Trp⁶⁴Arg polymorphism of the β₃-adrenergic receptor gene, pre-pregnancy obesity and risk of pre-eclampsia. J Matern Fetal Neonatal Med 2005, 17(1): 19-28.

Alcoholism

Kim H, Hutter CM, Monks SA, Edwards KL. Comparison of single-nucleotide polymorphisms and microsatellites in detecting quantitative trait loci for alcoholism: The Collaborative Study on the Genetics of Alcoholism. BMC Genet. 6 Suppl 1: S5, Dec/30/2005.

Smoking

Goode EL, Badzioch MD, Kim H, Gagnon F, Rozek LS, Edwards KL, Jarvik GP. Multiple Genome-Wide Analyses of Smoking Behavior in the Framingham Heart Study. BMC Genetics 2003 Suppl 1: p. S102.

Down's Syndrome

Doria-Rose VP, Kim HS, Augustine E, Edwards KL. Parity and the risk of Down syndrome. Am J Epidemiol 2003; 158(6) p. 503-8.

Doria-Rose VP, Edwards KL. Doria-Rose and Edwards respond to "Parity and Down's Syndrome". Am J Epidemiol 2033; 158(6) p. 512-3.

Cancer

Sieh W, Edwards KL, Fitzpatrick AL, Srinouanprachanh SL, Farin FM, Monks SA, Kronmal RA, Eaton DL. Genetic Susceptibility to Prostrate Cancer: Prostate-specific Antigen and its Interaction with the Androgen Receptor. Cancer Causes Control. 2006 Mar; 17 (2):187-97.

Su, Y.A., M.M. Lee, C.M. Hutter and P.S. Meltzer, Characterization of a highly conserved gene (OS4) amplified with CDK4 in human sarcomas. Oncogene, 15(11): 1289-94. 1997.

Su, Y.A., C.M. Hutter, J.M. Trent and P.S. Meltzer, Complete sequence analysis of a gene (OS-9) ubiquitously expressed in human tissues and amplified in sarcomas. Mol Carcinog, 15(4): 270-5. 1996.

Neurological Conditions

Zabetian CP, Hutter CM, Yearout D, Lopez AN, Factor SA, Griffith A, Leis BC, Bird TD, Nutt JG, Higgins DS, Roberts JW, Kay DM, Edwards KL, Samii A, Payami H. LRRK2 G2019S in Families with Parkinson's Disease Originating from Europe and the Middle East: Evidence for Two Distinct Founding Events Beginning Two Millennia Ago. American Journal of Human Genetics. 2006 Oct; 79(4):752-8.

Ramos EM, Lin TM, Larson EB, Maezawa I, Tseng L, Edwards KL, Schellenberg GD, John Hansen A, Kukull WA, Jin LW, Tumor necrosis factor alpha and interleukin 10 promoter region polymorphisms and risk of late-onset Alzheimer's disease. Archives of Neurology. 2006 Aug;63(8):1165-9.

Cystic Fibrosis

McKone EF, Emerson SS, Edwards KL, Aitken ML. The influence of Cystic Fibrosis genotype on mortality. Lancet 2003;361:1671-6.

Liver Transplantation

Hebert MF, Dowling ALS, Gierwatowski C, Lin YS, Edwards KL, Davis CL, Marsh CL, Schuetz EG, Thummel KE. Association between MDR1 genotype and post liver transplantation rental dysfunction in patients receiving calcineurin inhibitors. Pharmacogenetics 2003, 13(11): p. 661-674.