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Center on Human Development and Disability | ||||||||
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Dr. Bamford studies synaptic function and regulation of presynaptic activity. Evaluation of striatal function in the brain is paramount to understanding a number of important human physiological and pathological conditions, including the response to psychostimulants and motor disorders such as Parkinson and Huntington disease. Bamford and colleagues are investigating the function of the mammalian corticostriatal system, the collection of neurons that connect the cerebral cortex and striatum, and its role in psychostimulant addiction and motor disorders, including dopamine-depletion and Huntington disease. He is also evaluating pharmacological alternatives for the improved treatment of addiction, Parkinson disease, and Huntington disease as well as how psychostimulant withdrawal affects the release of glutamate from cortical projections to the striatum. University of Washington • Center on Human Development and Disability Box 357920 • Seattle WA 98195-7920 USA • 206-543-7701 •chdd@u.washington.edu Copyright © 1996—2008 Center on Human Development and Disability. Updated: July 20, 2006 |
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