Research
Emphasis Areas

Research Affiliates

Core Services
Behavioral Science Core

Brain Imaging Core

Cellular Morphology Core

Genetics Core

Infant Primate Research Laboratory Core

Instrument Development Laboratory Core

Donald Born, M.D., Ph.D.

Clinical Assistant Professor of Pathology
Research Affiliate, Center on Human Development and Disability
dborn@u.washington.edu
206-731-6315
University of Washington, Box 357470
Seattle, WA 98195-6480

Dr. Born focuses his research on links between neuronal and glial proliferation and survival. He investigates roles of intrinsic and extrinsic regulators and collaborates on anatomical studies of brain tissue from humans and animals to advance understanding of epilepsy, brain injury, and neoplasia.

Born and colleagues recently documented morphological changes in a rodent animal model of post-traumatic epilepsy that suggest cortical and hippocampal contributions to epileptogenesis. Other research involves investigating an animal (sheep) model of fetal ethanol exposure. Born also studies development (aberrant neuronal-glial differentiation in Taylor-type focal cortical dysplasia, type IIA/B) and cycle variation with differentiation in neoplasia (NeuN expression correlates with reduced mitotic index of neoplastic cells in central neurocytomas). In addition, pilot experiments are underway to study progenitor cell differentiation contributing to glial cell neoplasia.

Donald Born's web page

CHDD Outlook article

University of Washington • Center on Human Development and Disability Box 357920 • Seattle WA 98195-7920 USA • 206-543-7701 •chdd@u.washington.edu