Research
Emphasis Areas

Research Affiliates

Core Services
Behavioral Science Core

Brain Imaging Core

Cellular Morphology Core

Genetics Core

Infant Primate Research Laboratory Core

Instrument Development Laboratory Core

Mark Bothwell, Ph.D.

Professor of Physiology & Biophysics
Research Affiliate, Center on Human Development and Disability
mab@u.washington.edu
206-543-7924
University of Washington, Box 357290
Seattle, WA 98195-7290

Dr. Bothwell's research focuses on the regulatory functions of growth factors, particularly the role of growth factors in mediating trophic interactions in the developing nervous system. His laboratory is also interested in the functions of growth factors in the processes of memory and learning, in the repair of nervous system injury, and in neurodegenerative conditions.

Bothwell's studies are focused primarily on a family of neurotrophic growth factors known as neurotrophins and on their receptors. However, as neurotrophin receptors are multifunctional proteins that influence the function of a variety of membrane proteins, studies of neurotrophin receptor function are not limited to studies of neurotrophin action but encompass a variety of signaling systems including signaling responsible for restricting the capacity of damaged brain and spinal cord tissue to regenerate.

Mark Bothwell's web page

University of Washington • Center on Human Development and Disability Box 357920 • Seattle WA 98195-7920 USA • 206-543-7701 •chdd@u.washington.edu