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Center on Human Development and Disability
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CHDD is located on the Lake Washington Ship Canal

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Elaine Faustman, Ph.D.

Professor of Environmental Health
Research Affiliate, Center on Human Development and Disability

faustman@uw.edu

206-685-2269
University of Washington
Box 354695
Seattle, WA 98195-4695

Dr. Faustman

The long range objective of Dr. Faustman's research is two-fold: to identify biochemical mechanisms of developmental neurotoxicity and to develop new approaches for the evaluation and characterization of health risks from environmental agents. Because 70% of human birth defects have an unknown etiology, the identification of additional preventable causes of birth defects is extremely important for improving public health. One key aim of her research is to understand molecular pathways that control normal brain cell proliferation, differentiation, and apoptosis. Faustman’s group is working to understand the biochemical, molecular, and exposure mechanisms that define children’s susceptibility to environmental chemicals. A focus of her research has been on pesticides and to assess pesticide risks to normal childhood development and learning. Research investigations in her laboratory include understanding the potential for impacts of neurodevelopmental toxicants such as metals (methylmercury and arsenic), pesticides (organophosphates), and engineered nano materials on brain development. Faustman’s laboratory is also evaluating genomically conserved cell signaling pathways (such as P53 and P21 cell cycle check point pathways) in animal models to better understand the critical role they play in normal human brain development. This research will assist in understanding how such pathways may be altered by the environment resulting in abnormal neurodevelopment. Faustman has been very active in establishing the Pacific NW Center for the NCS and many lessons learned from this planning phase for the longitudinal cohort were learned. Recently, Faustman's lab was awarded a Predictive Toxicology Center from the USEPA that will allow them to explore the use of organotypic in vitro cell systems to predict the potential for environmental agents to alter human development.


Elaine Faustman's School of Public Health webpage


University of Washington • Center on Human Development and Disability • Box 357920 • Seattle WA 98195-7920 USA • 206-543-7701 • chdd@uw.edu