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Clifford Hume, M.D., Ph.D.

Associate Professor of Otolaryngology/Head & Neck Surgery
Research Affiliate, Center on Human Development and Disability
hume@uw.edu
206-543-5230
University of Washington
Box 357923
Seattle, WA 98195-7923

Dr. Hume's research focuses on perturbations of inner ear formation or altered function of components of the auditory signal transduction pathways in congenital hearing loss and the degeneration of sensory hair cells and their associated sensory neurons (spiral ganglion), which accounts directly or indirectly for most acquired hearing loss. His long-term goal is to identify the molecular signals that regulate the formation of hair cells and their neuronal connections during development and to use these signals to develop new strategies to treat human hearing loss.

Hume's current projects include afferent innervation of the postnatal cochlea, transcriptional regulation of hair cell development, and development of viral vectors for inner ear gene therapy and hair cell regeneration. He also heads a feasibility study of hybrid cochlear implants.

Cliff Hume's Molecular Therapeutics of Hearing Loss Lab web page

University of Washington • Center on Human Development and Disability Box 357920 • Seattle WA 98195-7920 USA • 206-543-7701 • chdd@uw.edu