Research
Emphasis Areas

Research Affiliates

Core Services
Behavioral Science Core

Brain Imaging Core

Cellular Morphology Core

Genetics Core

Infant Primate Research Laboratory Core

Instrument Development Laboratory Core

Sandra Juul, M.D., Ph.D.

Associate Professor of Pediatrics
Research Affiliate, Center on Human Development and Disability
sjuul@u.washington.edu
206-221-6814
University of Washington, Box 356320
Seattle, WA 98195-6320

Dr. Juul is principal investigator on studies focusing on the neuroprotective effects of erythropoietin (Epo) in neonatal models of brain injury. She has identified Epo and its receptor in the developing human brain, demonstrated the functionality of the Epo receptor on cultured neurons, and documented Epo in the spinal fluid of human neonates. Her research shows that Epo protects the neonatal brain from injury due to hypoxia and oxidative injury.

Juul’s ultimate goal is to identify new therapeutic approaches to neonatal brain injury, determine whether they are safe and effective, and if so, bring these new treatments from the laboratory to the bedside. Using a variety of approaches and several animal models, she is working to optimize Epo treatment in the developing brain at risk for injury. This work includes studies of pharmacokinetics, drug dosing, and duration of therapy as well as identifying mechanisms of Epo neuroprotection and possible synergistic treatments.

CHDD Outlook article

University of Washington • Center on Human Development and Disability Box 357920 • Seattle WA 98195-7920 USA • 206-543-7701 • chdd@u.washington.edu