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Center on Human Development and Disability | ||||||||
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Collaborative |
Dr. Kimelman uses animal models (primarily zebrafish and frogs) to study signaling pathways within and among cells that are critical to the development of vertebrate embryos. Results from his research may lead to a better understanding of developmental disorders caused by errors in embryonic development. A major research focus is the Wnt signaling pathway, which is of critical importance in a wide array of biological processes, from the regulation of early embryonic development to the control of stem cell growth. Dr. Kimelman’s team has determined several of the key intracellular interactions that regulate this pathway, including the kinase GSK3 and an inhibitor of this enzyme. The Kimelman Lab UW Department of Biochemistry University of Washington • Center on Human Development and Disability Box 357920 • Seattle WA 98195-7920 USA • 206-543-7701 •chdd@uw.edu Copyright © 1996—2013 Center on Human Development and Disability. Updated: November 17, 2011 |
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