|CHDD||Home | Site Map | Search | Directory | Admin Services||
||Center on Human Development and Disability|
|About CHDD | IDDRC | UCEDD|
Dr. Leverenz leads research on the neuropathology, anatomy, and clinical neurology of degenerative neurological diseases such as Alzheimer's. His current work incorporates a series of patho-anatomical studies of early Alzheimer's disease pathology in Down syndrome, mild Alzheimer's disease and normal aging. Because Alzheimer's pathology occurs much more frequently and earlier among people with Down syndrome, Leverenz has begun including adults from this population in his research. His goal is to gain understanding of the aging process in people with Down syndrome and thus gain understanding of how Alzheimer's disease develops in aging persons with and without Down syndrome.
In his effort to understand early development of Alzheimer's, Leverenz is studying roles of two proteins associated the disease–tau and beta amyloid–and their abnormal appearance before typical pathological changes of Alzheimer's (senile plaques and neurofibrillary tangles). Examining the earliest changes in these proteins may elucidate the early pathological progression of Alzheimer's disease.
James Leverenz's UW Alheimer's Disease Research Center web page
University of Washington • Center on Human Development and Disability Box 357920 • Seattle WA 98195-7920 USA • 206-543-7701 • email@example.com
Copyright © 1996—2013 Center on Human Development and Disability. Updated: November 17, 2011