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Dr. Mourad's research lies at the intersection of physics - generally diagnostic or therapeutic ultrasound - and the nervous systems (central and peripheral). In particular, he has active projects on the use of ultrasound to assay the presence and extent of traumatic brain injury. This includes novel imaging modalities sensitive to brain-tissue stiffness. Mourad also has active projects on the use of intense focused ultrasound to palpate deep structures within the body as a non-invasive evocative test to determine the location of peripheral pain generators within the body as well as to track the management of pain associated with those pain generators, including the influence of central sensitization on pain. In addition, recent in vivo work by Mourad suggests that too much diagnostic ultrasound in utero can alter subsequent behavior of mice in a way consistent with a variety of neurodevelopmental disorders, including autism. Finally, Dr. Mourad has completed in vivo work supporting the use of modulated focused ultrasound to modulate brain function.
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