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Sean Murphy, Ph.D.

Professor of Neurological Surgery
Research Affiliate, Center on Human Development and Disability
University of Washington
Box 356470
Seattle, WA 98195-6470

Dr. Murphy

Dr. Murphy studies mechanisms that can protect the brain from damage caused by strokes. Strokes can occur at any age, and are especially devastating in infants. He currently focuses on the potential of two drugs, progesterone and granulocyte stimulating factor (G-CSF), that suppress specific aspects of harmful, post-stroke brain inflammation in animals, resulting in smaller areas of tissue death and preservation of cognitive and motor skills. Murphy also studies the effects of these drugs on the development of new neural cells after stroke. Other research involves targeting of iNOS and nNOS isoforms to discrete cellular compartments, NO in neuroprotection and neurogenesis, and NO and the host response to infection.

Sean Murphy Lab web page

University of Washington • Center on Human Development and Disability Box 357920 • Seattle WA 98195-7920 USA • 206-543-7701 •